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Combination STING agonist and NK cellular therapy in patient derived organotypic tumor spheroids Lizotte, Patrick H.; Ivanova, Elena; Park, Sung; Spicer, Nathaniel; Kivlehan, Sophie; Gjeci, Iliana; Kiesgen, Stefan; Appleman, Vicky; Talarico, LeeAnn; Tolstorukov, Michael Y.; Bueno, Raphael; Barbie, David A.; Paweletz, Cloud P. 分享 收藏
Functional profiling in lung tumor explants show contributions of the tumor microenvironment to response of Dato-DXdex vivo Yasuda, Satoru; Ivanova, Elena; Vo, Ha V.; Kivlehan, Sophie; Gjeci, Iliana; Ha, Minh; Lizotte, Patrick; Bueno, Raphael; Barbie, David A.; Paweletz, Cloud P. 分享 收藏
Multiomics analysis of impact of CD8+and other cell populations in STING agonist treated ex vivo mesothelioma samples Ivanova, Elena; Park, Sung R.; Zlota, Ari P.; Spicer, Nathaniel; Ha, Minh; Kivlehan, Sophie; Gjeci, Iliana; Innocenti, Simona; Zasadil, Lauren; Lizotte, Patrick; Tolstorukov, Michael Y.; Ding, Kai; Abu-Yousif, Adnan O.; Raizer, Jeffrey; Appleman, Vicky A.; Bueno, Raphael; Barbie, David A.; Paweletz, Cloud P. 分享 收藏
Co-clinical endometrial cancer (EC) patient-derived organoids (PDO) to assess functional effects of replication stress (RS)-targeting agents Ivanova, Elena; Saldanha, Aisha L.; Roychoudhury, Shrabasti; Kochupurakkal, Bose; Zlota, Ari P.; Padrick, Clare E.; Vo, Ha V.; Greenberg, Eli K.; Sawyer, Hannah; Feeney, Carina; Qi, Courtney H.; Narayan, Swati; Curtis, Jennifer D.; Tayob, Nabihah; Nucci, Marisa R.; Konstantinopoulos, Panagiotis; Chowdhury, Dipanjan; Shapiro, Geoffrey; Paweletz, Cloud P.; Matulonis, Ursula A.; Liu, Joyce F. 分享 收藏
Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects 亲和力微调抗CAIX car-t细胞减轻中靶肿瘤外副作用 Wang, Yufei; Buck, Alicia; Piel, Brandon; Zerefa, Luann; Murugan, Nithyassree; Coherd, Christian D.; Miklosi, Andras G.; Johal, Haraman; Bastos, Ricardo Nunes; Huang, Kun; Ficial, Miriam; Laimon, Yasmin Nabil; Signoretti, Sabina; Zhong, Zhou; Hoang, Song-My; Kastrunes, Gabriella M.; Grimaud, Marion; Fayed, Atef; Yuan, Hsien-Chi; Nguyen, Quang-De; Thai, Tran; Ivanova, Elena V.; Paweletz, Cloud P.; Wu, Ming-Ru; Choueiri, Toni K.; Wee, Jon O.; Freeman, Gordon J.; Barbie, David A.; Marasco, Wayne A. 分享 收藏
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Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer Nardi, Francesca; Perurena, Naiara; Schade, Amy E.; Li, Ze-Hua; Ngo, Kenneth; Ivanova, Elena, V; Saldanha, Aisha; Li, Chendi; Gokhale, Prafulla C.; Hata, Aaron N.; Barbie, David A.; Paweletz, Cloud P.; Jaenne, Pasi A.; Cichowski, Karen 分享 收藏
FOXA2 controls the anti-oxidant response in FH-deficient cells Rogerson, Connor; Sciacovelli, Marco; Maddalena, Lucas A.; Pouikli, Andromachi; Segarra-Mondejar, Marc; Valcarcel-Jimenez, Lorea; Schmidt, Christina; Yang, Ming; Ivanova, Elena; Kent, Joshua; Mora, Ariane; Cheeseman, Danya; Carroll, Jason S.; Kelsey, Gavin; Frezza, Christian 分享 收藏
Individualizing treatment using patient derived organoids, BH3 profiling and microfluidics: A proof of concept in a patient with low-grade serous ovarian carcinoma Meisenheimer, Brittany; Vo, Ha V.; McQueeney, Kelley E.; Saldanha, Aisha L.; Feeney, Carina; Qi, Courtney H.; Narayan, Swati; Curtis, Jennifer D.; Nucci, Marisa R.; Letai, Anthony; Paweletz, Cloud P.; Liu, Joyce F.; Matulonis, Ursula A.; Ivanova, Elena 分享 收藏
Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate ontarget off-tumor side effects Wang, Yufei; Buck, Alicia; Kastrunes, Gabriella; Abbas, Rabia; Lynch, Michael; Zhong, Zhou; Hoang, Song-My; Miklosi, Andras; Huang, Kun; Cho, Jae-Won; Grimaud, Marion; Razimbaud, Cecile; Chang, Matthew; Fayed, Atef; Apollon, Audrey; Murugan, Nithyassree; Li, Ze-Hua; Thai, Tran; Zerefa, Luann; Piel, Brandon; Ivanova, Elena; Cameron, Amy; Nguyen, Quang-De; Zhu, Zhu; Wei, Kevin; Laimon, Yasmin Nabil 分享 收藏
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Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours Konstantinopoulos, Panagiotis A.; Cheng, Su-Chun; Supko, Jeffrey G.; Polak, Madeline; Wahner-Hendrickson, Andrea E.; Ivy, S. Percy; Bowes, Brittany; Sawyer, Hannah; Basada, Patrice; Hayes, Martin; Curtis, Jennifer; Horowitz, Neil; Wright, Alexi A.; Campos, Susana M.; Ivanova, Elena, V; Paweletz, Cloud P.; Palakurthi, Sangeetha; Liu, Joyce F.; D'Andrea, Alan D.; Gokhale, Prafulla C.; Chowdhury, Dipanjan; Matulonis, Ursula A.; Shapiro, Geoffrey, I 分享 收藏
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Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer Eser, Pinar Ozden; Paranal, Raymond M.; Son, Jieun; Ivanova, Elena; Kuang, Yanan; Haikala, Heidi M.; To, Ciric; Okoro, Jeffrey J.; Dholakia, Kshiti H.; Choi, Jihyun; Eum, Yoonji; Ogino, Atsuko; Missios, Pavlos; Ercan, Dalia; Xu, Man; Poitras, Michael J.; Wang, Stephen; Ngo, Kenneth; Dills, Michael; Yanagita, Masahiko; Lopez, Timothy; Lin, Mika; Tsai, Jeanelle; Floch, Nicolas; Chambers, Emily S.; Heng, Jennifer; Anjum, Rana; Santucci, Alison D.; Michael, Kesi; Schuller, Alwin G.; Cross, Darren; Smith, Paul D.; Oxnard, Geoffrey R.; Barbie, David A.; Sholl, Lynette M.; Bahcall, Magda; Palakurthi, Sangeetha; Gokhale, Prafulla C.; Paweletz, Cloud P.; Daley, George Q.; Janne, Pasi A. 分享 收藏
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Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade Sehgal, Kartik; Portell, Andrew; Ivanova, Elena, V; Lizotte, Patrick H.; Mahadevan, Navin R.; Greene, Jonathan R.; Vajdi, Amir; Gurjao, Carino; Teceno, Tyler; Taus, Luke J.; Thai, Tran C.; Kitajima, Shunsuke; Liu, Derek; Tani, Tetsuo; Noureddine, Moataz; Lau, Christie J.; Kirschmeier, Paul T.; Liu, David; Giannakis, Marios; Jenkins, Russell W.; Gokhale, Prafulla C.; Goldoni, Silvia; Pinzon-Ortiz, Maria; Hastings, William D.; Hammerman, Peter S.; Miret, Juan J.; Paweletz, Cloud P.; Barbie, David A. 分享 收藏
Cell-cell coupling and DNA methylation abnormal phenotypes in the after-hours mice 小时后小鼠的细胞-细胞偶联和DNA甲基化异常表型 Tinarelli, Federico; Ivanova, Elena; Colombi, Ilaria; Barini, Erica; Balzani, Edoardo; Garcia, Celina Garcia; Gasparini, Laura; Chiappalone, Michela; Kelsey, Gavin; Tucci, Valter 分享 收藏
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