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Yoshio Hayashi

Tokyo University of Pharmacy and Life Sciences

56H指数
619论文数
1.3W被引数
收录论文 122
发表时间
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Myostatin Inhibitory D-Peptides Induce Skeletal Muscle Hypertrophy along with Alteration of Bioactive Sphingolipid Metabolism肌生成抑制蛋白抑制性D-肽诱导骨骼肌肥大并改变生物活性鞘脂代谢
errACS Pharmacology & Translational Science
IF3.7
err2026-05-26
err0
errOAAI
errKatsuya Morito; Natsuki Nishikawa; Keisuke Hitachi; Rina Tamaki; Minori Nishikawa; Yoshio Hayashi; Kunihiro Tsuchida; Kentaro Takayama
err分享
err收藏
A Cysteine-Dependent Peptide Cyclase with Broad Substrate Tolerance Enables Chemoenzymatic Synthesis of Macolacin Analogs一种半胱氨酸依赖性肽环化酶，具有广泛的底物耐受性，能够实现麦考拉菌素类似物的化学酶法合成
errACS Chemical Biology
IF3.8
err2026-05-22
err0
errOAAI
errMiyu Morohashi; Sho Konno; Koki Yamashita; Kyoga Kamijo; Akihiro Taguchi; Masaki Mishima; Atsuhiko Taniguchi; Yoshio Hayashi
err分享
err收藏
Discovery of a Pentapeptide Antagonist to Human Neuromedin U Receptor 1
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-05-24
err1
PREAI
errTakayama, Kentaro; Mori, Kenji; Sasaki, Yu; Taguchi, Akihiro; Taniguchi, Atsuhiko; Miyazato, Mikiya; Hayashi, Yoshio
err分享
err收藏
Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead
errACS CHEMICAL BIOLOGY
IF3.8
err2024-04-26
err3
PREAI
errYamauchi, Yuki; Konno, Sho; Omura, Noriko; Yoshioka, Narumi; Hingst, Alexandra; Guetschow, Michael; Mueller, Christa E.; Taguchi, Akihiro; Taniguchi, Atsuhiko; Kawaguchi, Atsushi; Hayashi, Yoshio
err分享
err收藏
Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-12-04
err0
PREAI
errOmura, Noriko; Taguchi, Akihiro; Kuwahara, Tomoki; Hamada, Keisuke; Watanabe, Mizuki; Nakakuki, Masanori; Konno, Sho; Takayama, Kentaro; Taniguchi, Atsuhiko; Nomura, Toshifumi; Shuto, Satoshi; Hayashi, Yoshio
err分享
err收藏
X-Ray Conformation and Structure-Activity Relationships of MA026, a Reversible Tight Junction Opener
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-06-23
err0
PREAI
errMukaiyama, Minagi; Uchiyama, Chihiro; Fukuda, Akane; Nakazawa, Yoshiki; Kuramochi, Yuka; Shibata, Yudai; Konno, Sho; Muguruma, Kyohei; Matsugaki, Naohiro; Asari, Tomo; Ogawa, Kazuyoshi; Taguchi, Akihiro; Takayama, Kentaro; Taniguchi, Atsuhiko; Nagumo, Yoko; Senda, Toshiya; Hayashi, Yoshio; Usui, Takeo
err分享
err收藏
Novel role for RbAp48 in tissue-specific, estrogen deficiency-dependent apoptosis in the exocrine glands
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err36
errOAAI
errIshimaru, N; Arakaki, R; Omotehara, F; Yamada, K; Mishima, K; Saito, I; Hayashi, Y
err分享
err收藏
Increasing Skeletal Muscle Mass in Mice by Non-Invasive Intramuscular Delivery of Myostatin Inhibitory Peptide by Iontophoresis
errPHARMACEUTICALS
IF4.8
err2023-03-06
err5
errOAAI
errMichiue, Kohki; Takayama, Kentaro; Taniguchi, Atsuhiko; Hayashi, Yoshio; Kogure, Kentaro
err分享
err收藏
Inactivation of myostatin by photooxygenation using functionalized d-peptides
errRSC MEDICINAL CHEMISTRY
IF3.6
err2023-01-01
err0
errOAAI
errOkamoto, Hideyuki; Murano, Shuko Amber; Ikekawa, Kaoru; Katsuyama, Masahiro; Konno, Sho; Taguchi, Akihiro; Takayama, Kentaro; Taniguchi, Atsuhiko; Hayashi, Yoshio
err分享
err收藏
Chemical Synthesis of an HIV-1 Protease Analog with Some Amides in a Polypeptide Main Chain Replaced by Disulfide Bonds
errBULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
IF3.8
err2022-06-11
err4
PREAI
errCui, Yan; Taguchi, Akihiro; Shida, Hayate; Konno, Sho; Takayama, Kentaro; Taniguchi, Atsuhiko; Hayashi, Yoshio
err分享
err收藏
Development of Myostatin Inhibitory D-Peptides to Enhance the Potency, Increasing Skeletal Muscle Mass in Mice
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-02-14
err12
errOAAI
errTakayama, Kentaro; Hitachi, Keisuke; Okamoto, Hideyuki; Saitoh, Mariko; Odagiri, Miki; Ohfusa, Rina; Shimada, Takahiro; Taguchi, Akihiro; Taniguchi, Atsuhiko; Tsuchida, Kunihiro; Hayashi, Yoshio
err分享
err收藏
3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-07-27
err92
PREAI
errKonno, Sho; Kobayashi, Kiyotaka; Senda, Miki; Funai, Yuta; Seki, Yuta; Tamai, Ikumi; Schaekel, Laura; Sakata, Kyousuke; Pillaiyar, Thanigaimalai; Taguchi, Akihiro; Taniguchi, Atsuhiko; Guetschow, Michael; Mueller, Christa E.; Takeuchi, Koh; Hirohama, Mikako; Kawaguchi, Atsushi; Kojima, Masaki; Senda, Toshiya; Shirasaka, Yoshiyuki; Kamitani, Wataru; Hayashi, Yoshio
err分享
err收藏
Proposal for the binding mode of the 23-mer inhibitory peptide to myostatin
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2021-06-01
err3
PREAI
errAsari, Tomo; Ikeyama, Hiroaki; Taguchi, Akihiro; Taniguchi, Atsuhiko; Hayashi, Yoshio; Takayama, Kentaro
err分享
err收藏
Development of a High-Affinity Antibody-Binding Peptide for Site-Specific Modification
errCHEMMEDCHEM
IF3.4
err2021-03-25
err4
PREAI
errMuguruma, Kyohei; Osawa, Rento; Fukuda, Akane; Ishikawa, Naoto; Fujita, Konomi; Taguchi, Akihiro; Takayama, Kentaro; Taniguchi, Atsuhiko; Ito, Yuji; Hayashi, Yoshio
err分享
err收藏
Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2021-03-18
err10
PREAI
errKobayakawa, Takuya; Azuma, Chika; Watanabe, Yuki; Sawamura, Shunsuke; Taniguchi, Atsuhiko; Hayashi, Yoshio; Tsuji, Kohei; Tamamura, Hirokazu
err分享
err收藏
Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis通过全合成和生物合成基因聚类分析建立的天然环状酯肽MA026的结构修订
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2021-03-08
err4
PREAI
errUchiyama, Chihiro; Fukuda, Akane; Mukaiyama, Minagi; Nakazawa, Yoshiki; Kuramochi, Yuka; Muguruma, Kyohei; Arimoto, Mitsue; Ninomiya, Akihiro; Kako, Koichiro; Katsuyama, Yohei; Konno, Sho; Taguchi, Akihiro; Takayama, Kentaro; Taniguchi, Atsuhiko; Nagumo, Yoko; Usui, Takeo; Hayashi, Yoshio
err分享
err收藏
Synthesis and biological evaluation of a monocyclic Fc-binding antibody-recruiting molecule for cancer immunotherapy
errRSC MEDICINAL CHEMISTRY
IF3.6
err2021-01-01
err5
errOAAI
errSasaki, Koichi; Muguruma, Kyohei; Osawa, Rento; Fukuda, Akane; Taniguchi, Atsuhiko; Kishimura, Akihiro; Hayashi, Yoshio; Mori, Takeshi; Katayama, Yoshiki
err分享
err收藏
A chemically stable peptide agonist to neuromedin U receptor type 2
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2020-05-01
err11
PREAI
errTakayama, Kentaro; Mori, Kenji; Tanaka, Akiko; Sasaki, Yu; Sohma, Yuko; Taguchi, Akihiro; Taniguchi, Atsuhiko; Sakane, Toshiyasu; Yamamoto, Akira; Miyazato, Mikiya; Minamino, Naoto; Kangawa, Kenji; Hayashi, Yoshio
err分享
err收藏
Disulfide-Driven Cyclic Peptide Synthesis of Human Endothelin-2 with a Solid-Supported Npys-Cl
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2019-12-03
err12
PREAI
errTaguchi, Akihiro; Kobayashi, Kiyotaka; Cui, Yan; Takayama, Kentaro; Taniguchi, Atsuhiko; Hayashi, Yoshio
err分享
err收藏
New Negamycin-Based Potent Readthrough Derivative Effective against TGA-Type Nonsense Mutations新的基于Negamycin的有效通读衍生物可有效对抗TGA型无义突变
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2019-09-23
err19
errOAAI
errHamada, Keisuke; Omura, Noriko; Taguchi, Akihiro; Baradaran-Heravi, Alireza; Kotake, Masaya; Arai, Misaki; Takayama, Kentaro; Taniguchi, Atsuhiko; Roberge, Michel; Hayashi, Yoshio
err分享
err收藏

研究方向

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