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The Role of NOXA in Venetoclax Treatment Response in Multiple Myeloma NOXA在Venetoclax治疗反应中的作用在多发性骨髓瘤中的作用 Shivaram, Suganti; Yan, Huihuang; Tang, Hongwei; Anderson, Hans M.; Kaddoura, Marcella; Wiedmeier-Nutor, J. Erin; Tian, Shulan; Howe, Michael; Bolarinwa, Abiola; Mendoza, Cinthya Zepeda; Gupta, Vikas A.; Lehman, Stacey; Mitsiades, Constantine S.; Bergsagel, P. Leif; Braggio, Esteban; Boise, Lawrence H.; Fonseca, Rafael; Maura, Francesco; Kumar, Shaji; Baughn, Linda B. 分享 收藏
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Editorial Expression of Concern: p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells Hideshima, Teru; Podar, Klaus; Chauhan, Dharminder; Ishitsuka, Kenji; Mitsiades, Constantine; Tai, Yu-Tzu; Hamasaki, Makoto; Raje, Noopur; Hideshima, Hiromasa; Schreiner, George; Nguyen, Aaron N.; Navas, Tony; Munshi, Nikhil C.; Richardson, Paul G.; Higgins, Linda S.; Anderson, Kenneth C. 分享 收藏
The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells (vol 21, pg 572, 2015) 亲环素A-CD147复合物促进多发性骨髓瘤细胞的增殖和归巢 (第21卷，572页，2015页) Zhu, Di; Wang, Zhongqiu; Zhao, Jian-Jun; Calimeri, Teresa; Meng, Jiang; Hideshima, Teru; Fulciniti, Mariateresa; Kang, Yue; Ficarro, Scott B.; Tai, Yu-Tzu; Hunter, Zachary; Mcmilin, Douglas; Tong, Haoxuan; Mitsiades, Constantine S.; Wu, Catherine J.; Treon, Steven P.; Dorfman, David M.; Pinkus, Geraldine; Munshi, Nikhil C.; Tassone, Pierfrancesco; Marto, Jarrod A.; Anderson, Kenneth C.; Carrasco, Ruben D. 分享 收藏
NSD2 overexpression drives multiple myeloma dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome Sobh, Amin; Encinas, Elena; Patel, Alisha; Surapaneni, Greeshma; Kaestner, Charlotte; Poullard, Janai; Clerio, Monica; Vasan, Karthik; Freeman, Tzipporah; Lv, Dongwen; Dupere-Richer, Daphne; Riva, Alberto; Barwick, Benjamin; Zhou, Daohong; Boise, Lawrence; Mitsiades, Constantine; Kim, Baek; Bennett, Richard; Chandel, Navdeep; Licht, Jonathan 分享 收藏
RETRACTION: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling (Retraction of Vol 63, Pg 5850, 2003) Tai, Yu-Tzu; Podar, Klaus; Catley, Laurence; Tseng, Yu-Hua; Akiyama, Masaharu; Shringarpure, Reshma; Burger, Renate; Hideshima, Teru; Chauhan, Dharminder; Mitsiades, Nicholas; Richardson, Paul; Munshi, Nikhil C.; Kahn, C. Ronald; Mitsiades, Constantine; Anderson, Kenneth C. 分享 收藏
RETRACTION: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein (Retraction of Vol 63, Pg 18, 2003) Akiyama, Masaharu; Hideshima, Teru; Hayashi, Toshiaki; Tai, Yu-Tzu; Mitsiades, Constantine S.; Mitsiades, Nicholas; Chauhan, Dharminder; Richardson, Paul; Munshi, Nikhil C.; Anderson, Kenneth C. 分享 收藏
RETRACTION: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications (Retraction of Vol 64, Pg 2846, 2004) Tai, Yu-Tzu; Catley, Laurence P.; Mitsiades, Constantine S.; Burger, Renate; Podar, Klaus; Shringpaure, Reshma; Hideshima, Teru; Chauhan, Dharminder; Hamasaki, Makoto; Ishitsuka, Kenji; Richardson, Paul; Treon, Steven P.; Munshi, Nikhil C.; Anderson, Kenneth C. 分享 收藏
RETRACTION: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line (Retraction of Vol 62, Pg 3876, 2002) Akiyama, Masaharu; Hideshima, Teru; Hayashi, Toshiaki; Tai, Yu-Tzu; Mitsiades, Constantine S.; Mitsiades, Nicholas; Chauhan, Dharminder; Richardson, Paul; Munshi, Nikhil C.; Anderson, Kenneth C. 分享 收藏
Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity (vol 16, pg 483, 2010) 肿瘤细胞特异性生物发光平台，用于鉴定基质诱导的抗癌药物活性变化 (第16卷，483页，2010页) McMillin, Douglas. W.; Delmore, Jake; Weisberg, Ellen; Negri, Joseph. M.; Geer, Corey. D.; Klippel, Steffen; Mitsiades, Nicholas; Schlossman, Robert. L.; Munshi, Nikhil. C.; Kung, Andrew. L.; Griffin, James. D.; Richardson, Paul. G.; Anderson, Kenneth. C.; Mitsiades, Constantine. S. 分享 收藏
The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells (vol 21, pg 572, 2015) 亲环素A-CD147复合物促进多发性骨髓瘤细胞的增殖和归巢 (第21卷，572页，2015页) Zhu, Di; Wang, Zhongqiu; Zhao, Jian-Jun; Calimeri, Teresa; Meng, Jiang; Hideshima, Teru; Fulciniti, Mariateresa; Kang, Yue; Ficarro, Scott B.; Tai, Yu-Tzu; Hunter, Zachary; Mcmilin, Douglas; Tong, Haoxuan; Mitsiades, Constantine S.; Wu, Catherine J.; Treon, Steven P.; Dorfman, David M.; Pinkus, Geraldine; Munshi, Nikhil C.; Tassone, Pierfrancesco; Marto, Jarrod A.; Anderson, Kenneth C.; Carrasco, Ruben D. 分享 收藏
Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers 单细胞功能基因组学揭示血癌对自然杀伤细胞的敏感性和抗性的决定因素 Dufva, Olli; Gandolfi, Sara; Huuhtanen, Jani; Dashevsky, Olga; Duan, Hanna; Saeed, Khalid; Klievink, Jay; Nygren, Petra; Bouhlal, Jonas; Lahtela, Jenni; Naatanen, Anna; Ghimire, Bishwa R.; Hannunen, Tiina; Ellonen, Pekka; Lahteenkaki, Hanna; Rumm, Pauliina; Theodoropoulos, Jason; Laajala, Essi; Harkonen, Jouni; Polonen, Petri; Heinaniemi, Merja; Hollmen, Maija; Yamano, Shizuka; Shirasaki, Ryosuke; Barbie, David A.; Roth, Jennifer A.; Romee, Rizwan; Sheffer, Michal; Lahdesmaki, Harri; Lee, Dean A.; Simoes, Ricardo De Matos; Kankainen, Matti; Mitsiades, Constantine S.; Mustjoki, Satu 分享 收藏
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies Chong, Stephen Jun Fei; Zhu, Fen; Dashevsky, Olga; Mizuno, Rin; Lai, Jolin X. H.; Hackett, Liam; Ryan, Christine E.; Collins, Mary C.; Iorgulescu, J. Bryan; Guieze, Romain; Penailillo, Johany; Carrasco, Ruben; Hwang, Yeonjoo C.; Munoz, Denise P.; Bouhaddou, Mehdi; Lim, Yaw Chyn; Wu, Catherine J.; Allan, John N.; Furman, Richard R.; Goh, Boon Cher; Pervaiz, Shazib; Coppe, Jean-Philippe; Mitsiades, Constantine S.; Davids, Matthew S. 分享 收藏
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias Simoes, Ricardo de Matos; Shirasaki, Ryosuke; Downey-Kopyscinski, Sondra L.; Matthews, Geoffrey M.; Barwick, Benjamin G.; Gupta, Vikas A.; Dupere-Richer, Daphne; Yamano, Shizuka; Hu, Yiguo; Sheffer, Michal; Dhimolea, Eugen; Dashevsky, Olga; Gandolfi, Sara; Ishiguro, Kazuya; Meyers, Robin M.; Bryan, Jordan G.; Dharia, Neekesh V.; Hengeveld, Paul J.; Bruggenthies, Johanna B.; Tang, Huihui; Aguirre, Andrew J.; Sievers, Quinlan L.; Ebert, Benjamin L.; Glassner, Brian J.; Ott, Christopher J.; Bradner, James E.; Kwiatkowski, Nicholas P.; Auclair, Daniel; Levy, Joan; Keats, Jonathan J.; Groen, Richard W. J.; Gray, Nathanael S.; Culhane, Aedin C.; McFarland, James M.; Dempster, Joshua M.; Licht, Jonathan D.; Boise, Lawrence H.; Hahn, William C.; Vazquez, Francisca; Tsherniak, Aviad; Mitsiades, Constantine S. 分享 收藏
Single- cell functional genomics of natural killer cell evasion by tumor cells Dufva, Olli; Gandolfi, Sara; Huuhtanen, Jani; Dashevsky, Olga; Saeed, Khalid; Klievink, Jay; Nygren, Petra; Bouhlal, Jonas; Lahtela, Jenni; Naatanen, Anna; Ghimire, Bishwa; Hannunen, Tiina; Ellonen, Pekka; Duan, Hanna; Theodoropoulos, Jason; Laajala, Essi; Harkonen, Jouni; Polonen, Petri; Heinaniemi, Merja; Yamano, Shizuka; Shirasaki, Ryosuke; Barbie, David; Roth, Jennifer; Romee, Rizwan; Sheffer, Michal; Lahdesmaki, Harri; Lee, Dean A.; Simoes, Ricardo De Matos; Kankainen, Matti; Mitsiades, Constantine S.; Mustjoki, Satu 分享 收藏
MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells Morimoto, Yoshihiro; Yamashita, Nami; Daimon, Tatsuaki; Hirose, Haruka; Yamano, Shizuka; Haratake, Naoki; Ishikawa, Satoshi; Bhattacharya, Atrayee; Fushimi, Atsushi; Ahmad, Rehan; Takahashi, Hidekazu; Dashevsky, Olga; Mitsiades, Constantine; Kufe, Donald 分享 收藏
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1 Mabe, Nathaniel W.; Huang, Min; Dalton, Guillermo N.; Alexe, Gabriela; Schaefer, Daniel A.; Geraghty, Anna C.; Robichaud, Amanda L.; Conway, Amy S.; Khalid, Delan; Mader, Marius M.; Belk, Julia A.; Ross, Kenneth N.; Sheffer, Michal; Linde, Miles H.; Ly, Nghi; Yao, Winnie; Rotiroti, Maria Caterina; Smith, Benjamin A. H.; Wernig, Marius; Bertozzi, Carolyn R.; Monje, Michelle; Mitsiades, Constantine S.; Majeti, Ravindra; Satpathy, Ansuman T.; Stegmaier, Kimberly; Majzner, Robbie G. 分享 收藏
Genome-scale screens identify factors regulating tumor cell responses to natural killer cells 基因组规模筛选确定调节肿瘤细胞对自然杀伤细胞反应的因素 Sheffer, Michal; Lowry, Emily; Beelen, Nicky; Borah, Minasri; Naffar-Abu Amara, Suha; Mader, Chris C.; Roth, Jennifer A.; Tsherniak, Aviad; Freeman, Samuel S.; Dashevsky, Olga; Gandolfi, Sara; Bender, Samantha; Bryan, Jordan G.; Zhu, Cong; Wang, Li; Tariq, Ifrah; Kamath, Govinda M.; Simoes, Ricardo De Matos; Dhimolea, Eugen; Yu, Channing; Hu, Yiguo; Dufva, Olli; Giannakis, Marios; Syrgkanis, Vasilis; Fraenkel, Ernest; Golub, Todd; Romee, Rizwan; Mustjoki, Satu; Culhane, Aedin C.; Wieten, Lotte; Mitsiades, Constantine S. 分享 收藏
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