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C

Chun-Wei Chen

city of hope comprehensive cancer center
H指数:41
被引数:8,704

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FANCM is required for the PAX3::FOXO1-driven oncogenic program in rhabdomyosarcoma

FANCM在横纹肌肉瘤中对于PAX3::FOXO1驱动的癌基因程序是必需的

Cell Reports
IF6.9
2026-09-010
OAAI
Delaney, Christopher D.; Lu, Min; Zimmerman, Seth P.; Meng, Yingying; Vaganay, Camille; Cerda-Smith, Christian G.; Liu, Annie; Hoj, Jacob P.; Killarney, Shane T.; Dillon, Kerry; Stewart, Amy E.; Huang, Kevin; Caci, Julia D.; White, Olivia; Puissant, Alexandre; Root, David E.; Shern, Jack F.; Eyler, Christine E.; Chen, Chun-Wei David; Counter, Christopher M.; Linardic, Corinne M.; Zou, Lee; Wood, Kris C.
Inhibition of ADSS2-mediated de novo AMP biosynthesis re-sensitizes acute myeloid leukemia to BH3 mimetics

抑制ADSS2-mediated从头合成AMP使急性髓系白血病对BH3模拟物重新敏感

Nature Cancer
IF28.5
2026-06-260
PRE
Xin He; Lei Zhang; Yang Li; Song-Bai Liu; Zheng Li; Haojie Dong; Genevieve E. Baker; Le Xuan Truong Nguyen; Wei Chen; Jinhui Wang; Zhilian Jia; Xiyuan Lu; Yi-Chun Lin; Zunsong Hu; Umesh Prasad Yadav; Meng Liu; Lianjun Zhang; Zhenhua Chen; Xiwei Wu; Jianjun Chen; Chun-Wei Chen; Stefano Tiziani; Weidong Hu; Ya-Huei Kuo; Sheng-Li Xue; Yong Zhang; Min Li; Yaoqiu Zhu; Guido Marcucci; Zhaohui Gu; J. Jefferson P. Perry; Yun Lyna Luo; Ling Li
Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

靶向METTL1/m7G轴作为髓系白血病的治疗策略

Blood
IF23.1
2025-12-010
PRE
Ren, Lili; Zhang, Honghai; Bobileva, Olga; Nai, Francesco; Bi, Hongjie; Baker, Genevieve; Dong, Lei; Guarin, David; Chan, Anthony; Hu, Weidong; Li, Wei; Leite, Irena; Wang, Xueer; Zhang, Xiaoxu; Xue, Meilin; Wang, Haixia; Qin, Hanjun; Wu, Xiwei; Ghoda, Lucy; Xu, Lin; Zhang, Bin; Li, Ling; Wunderlich, Mark; Mulloy, James; Jones, Courtney; O'leary, Sean; Rosen, Steven; Chen, Chun-Wei; Heisterkamp, Nora; Perry, J. Jefferson; Nam, Yunsun; Chen, Jianjun; Li, Xiaobo; Caflisch, Amedeo; Su, Rui
Disparate leukemia mutations converge on nuclear phase-separated condensates

异质性白血病突变汇聚于细胞核相分离凝聚体

Cell
IF42.5
2025-11-040
OA
Gandhar K. Datar; Elmira Khabusheva; Archish Anand; Joshua Beale; Marwa Sadek; Chun-Wei Chen; Evdokiia Potolitsyna; Nayara Alcantara-Contessoto; Guangyuan Liu; Josephine De La Fuente; Christina Dollinger; Anna Guzman; Alejandra Martell; Katharina Wohlan; Abhishek Maiti; Nicholas J. Short; S. Stephen Yi; Vibeke Andresen; Bjørn Tore Gjertsen; Brunangelo Falini; Rachel E. Rau; Lorenzo Brunetti; Nidhi Sahni; Margaret A. Goodell; Joshua A. Riback
Synergistic Efficacy of Dual Menin and PRMT5 Targeting Against NPM1 mutated and KMT2A- rearranged Leukemia

双Menin和PRMT5靶向治疗NPM1突变型和KMT2A重排型白血病的协同疗效

BLOOD
IF23.1
2024-11-050
PRE
Dolgikh, Nadezda; Rausch, Johanna; Steiner, Marlene; Schoenfeld, Jonas; Lahrmann, Catharina; Hilke, Nina; Molerio, Maria Alejandra Vila; Weisemann, Simon; Saura-Panella, Maria; Gallego-Crespo, Aaron; Theobald, Matthias; Sasca, Daniel; Chen, Chun-Wei David; Kuehn, Michael W. M.
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery
SCIENCE ADVANCES
IF12.5
2024-02-232
OAAI
Chan, Anthony K. N.; Han, Li; Delaney, Christopher D.; Wang, Xueer; Mukhaleva, Elizaveta; Li, Mingli; Yang, Lu; Pokharel, Sheela Pangeni; Mattson, Nicole; Garcia, Michelle; Wang, Bintao; Xu, Xiaobao; Zhang, Leisi; Singh, Priyanka; Elsayed, Zeinab; Chen, Renee; Kuang, Benjamin; Wang, Jinhui; Yuan, Yate-Ching; Chen, Bryan; Chan, Lai N.; Rosen, Steven T.; Horne, David; Muschen, Markus; Chen, Jianjun; Vaidehi, Nagarajan; Armstrong, Scott A.; Su, Rui; Chen, Chun-Wei
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2024-02-055
OAAI
Mattson, Nicole M.; Chan, Anthony K. N.; Miyashita, Kazuya; Mukhaleva, Elizaveta; Chang, Wen-Han; Yang, Lu; Ma, Ning; Wang, Yingyu; Pokharel, Sheela Pangeni; Li, Mingli; Liu, Qiao; Xu, Xiaobao; Chen, Renee; Singh, Priyanka; Zhang, Leisi; Elsayed, Zeinab; Chen, Bryan; Keen, Denise; Pirrotte, Patrick; Rosen, Steven. T.; Chen, Jianjun; Labarge, Mark A.; Shively, John E.; Vaidehi, Nagarajan; Rockne, Russell C.; Feng, Mingye; Chen, Chun-Wei
METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
JOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
2024-02-0113
OAAI
Xue, Meilin; Dong, Lei; Zhang, Honghai; Li, Yangchan; Qiu, Kangqiang; Zhao, Zhicong; Gao, Min; Han, Li; Chan, Anthony K. N.; Li, Wei; Leung, Keith; Wang, Kitty; Pokharel, Sheela Pangeni; Qing, Ying; Liu, Wei; Wang, Xueer; Ren, Lili; Bi, Hongjie; Yang, Lu; Shen, Chao; Chen, Zhenhua; Melstrom, Laleh; Li, Hongzhi; Timchenko, Nikolai; Deng, Xiaolan; Huang, Wendong; Rosen, Steven T.; Tian, Jingyan; Xu, Lin; Diao, Jiajie; Chen, Chun-Wei; Chen, Jianjun; Shen, Baiyong; Chen, Hao; Su, Rui
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation (vol 30, pg 1503, 2023)
CELL STEM CELL
IF20.4
2024-02-010
OA
Chen, Chun-Wei; Zhang, Linda; Dutta, Ravi; Niroula, Abhishek; Miller, Peter G.; Gibson, Christopher J.; Bick, Alexander G.; Reyes, Jaime M.; Lee, Yi -Tang; Tovy, Ayala; Gu, Tianpeng; Waldvogel, Sarah; Chen, Yi-Hung; Venters, Bryan J.; Esteve, Pierre -Olivier; Pradhan, Sriharsa; Keogh, Michael-Christopher; Natarajan, Pradeep; Takahashi, Koichi; Sperling, Adam S.; Goodell, Margaret A.
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG
NATURE COMMUNICATIONS
IF15.7
2023-09-212
OAAI
Kugler, Eitan; Madiwale, Shreyas; Yong, Darren; Thoms, Julie A. I.; Birger, Yehudit; Sykes, David B.; Schmoellerl, Johannes; Drakul, Aneta; Priebe, Valdemar; Yassin, Muhammad; Aqaqe, Nasma; Rein, Avigail; Fishman, Hila; Geron, Ifat; Chen, Chun-Wei; Raught, Brian; Liu, Qiao; Ogana, Heather; Liedke, Elisabeth; Bourquin, Jean-Pierre; Zuber, Johannes; Milyavsky, Michael; Pimanda, John; Prive, Gilbert G.; Izraeli, Shai
TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-09-205
OA
Wu, Gongwei; Yoshida, Noriaki; Liu, Jihe; Zhang, Xiaoyang; Xiong, Yuan; Heavican-Foral, Tayla B.; Mandato, Elisa; Liu, Huiyun; Nelson, Geoffrey M.; Yang, Lu; Chen, Renee; Donovan, Katherine A.; Jones, Marcus K.; Roshal, Mikhail; Zhang, Yanming; Xu, Ran; Nirmal, Ajit J.; Jain, Salvia; Leahy, Catharine; Jones, Kristen L.; Stevenson, Kristen E.; Galasso, Natasha; Ganesan, Nivetha; Chang, Tiffany; Wu, Wen-Chao; Louissaint, Abner; Debaize, Lydie; Yoon, Hojong; Dal Cin, Paola; Chan, Wing C.; Ho Sui, Shannan J.; Ng, Samuel Y.; Feldman, Andrew L.; Horwitz, Steven M.; Adelman, Karen; Fischer, Eric S.; Chen, Chun-Wei; Weinstock, David M.; Brown, Myles

研究方向

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陈建军 封面图
陈建军
H 指数:89论文数:620被引数:3.3万
S
Scott A. Armstrong
H 指数:92论文数:662被引数:4.0万
S
Sheela Pangeni Pokharel
H 指数:12论文数:40被引数:583
R
Rui Su
H 指数:53论文数:496被引数:1.8万
A
Anthony Chan
H 指数:16论文数:65被引数:2,729
L
Lu Yang
H 指数:24论文数:115被引数:2,438
S
Steven T. Rosen
H 指数:76论文数:720被引数:2.7万
M
Mingli Li
H 指数:35论文数:214被引数:3,413
M
Markus Müschen
H 指数:62论文数:455被引数:1.3万
Z
Zhenhua Chen
H 指数:28论文数:155被引数:5,202