未登录A high-throughput chemical genetic screen reveals SALL4-induced metabolic vulnerabilities in cancer
Tan, Justin L.; Li, Feng; Yeo, Joanna Z.; Yong, Kol Jia; Bassal, Mahmoud A.; Ng, Guo Hao; Lee, Y. Yin; Leong, Chung Yan; Tan, Hong Kee; Wu, Chan-Shuo; Liu, Bee Hui; Chan, Hon Man; Tan, Zi Hui; Chan, Yun Shen; Wang, Siyu; Lim, Zhi Han; Toh, Tan Boon; Hooi, Lissa; Low, Kia Ngee; Ma, Siming; Kong, Nikki R.; Stein, Alicia J.; Wu, Yue; Thangavelu, Matan T.; Suzuki, Atsushi; Periyasamy, Giridharan; Asara, John M.; Dan, Yock Young; Bonney, Glenn K.; Chow, Edward K.; Lu, Guo-Dong; Ng, Huck Hui; Kanagasundaram, Yoganathan; Ng, Siew; Tam, Wai Leong; Chai, Li; Tenen, Daniel G. .png)
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收藏New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative PhosphorylationTan, Justin L.; Li, Feng; Yeo, Joanna Z.; Yong, Kol Jia; Bassal, Mahmoud A.; Ng, Guo Hao; Lee, Y. Yin; Leong, Chung Yan; Tan, Hong Kee; Wu, Chan-Shuo; Liu, Hui; Chan, Tim H.; Tan, Zi Hui; Chan, Yun Shen; Wang, Siyu; Lim, Zhi Han; Toh, Tan Boon; Hooi, Lissa; Low, Kia Ngee; Ma, Siming; Kong, Nikki R.; Stein, Alicia J.; Wu, Yue; Thangavelu, Matan T.; Suzuki, Atsushi; Periyasamy, Giridharan; Asara, John M.; Dan, Yock Young; Bonney, Glenn K.; Chow, Edward K.; Lu, Guo-Dong; Ng, Huck Hui; Kanagasundaram, Yoganathan; Ng, Siew; Tam, Wai Leong; Tenen, Daniel G.; Chai, Li 分享 收藏 The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemiaNumata, Akihiko; Kwok, Hui Si; Kawasaki, Akira; Li, Jia; Zhou, Qi-Ling; Kerry, Jon; Benoukraf, Touati; Bararia, Deepak; Li, Feng; Ballabio, Erica; Tapia, Marta; Deshpande, Aniruddha J.; Welner, Robert S.; Delwel, Ruud; Yang, Henry; Milne, Thomas A.; Taneja, Reshma; Tenen, Daniel G. 分享 收藏 分享 收藏 Development of Novel Triazolo-Thiadiazoles from Heterogeneous Green Catalysis as Protein Tyrosine Phosphatase 1B InhibitorsBaburajeev, C. P.; Mohan, Chakrabhavi Dhananjaya; Ananda, Hanumappa; Rangappa, Shobith; Fuchs, Julian E.; Jagadish, Swamy; Siveen, Kodappully Sivaraman; Chinnathambi, Arunachalam; Alharbi, Sulaiman Ali; Zayed, M. E.; Zhang, Jingwen; Li, Feng; Sethi, Gautam; Girish, Kesturu S.; Bender, Andreas; Basappa; Rangappa, Kanchugarakoppal S. 分享 收藏 Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3Dai, Xiaoyun; Ahn, Kwang Seok; Kim, Chulwon; Siveen, Kodappully Sivaraman; Ong, Tina H.; Shanmugam, Muthu K.; Li, Feng; Shi, Jizhong; Kumar, Alan Prem; Wang, Ling Zhi; Goh, Boon Cher; Magae, Junji; Hui, Kam M.; Sethi, Gautam 分享 收藏 Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in VivoMohan, Chakrabhavi Dhananjaya; Bharathkumar, Hanumantharayappa; Bulusu, Krishna C.; Pandey, Vijay; Rangappa, Shobith; Fuchs, Julian E.; Shanmugam, Muthu K.; Dai, Xiaoyun; Li, Feng; Deivasigamani, Amudha; Hui, Kam M.; Kumar, Alan Prem; Lobie, Peter E.; Bender, Andreas; Basappa; Sethi, Gautam; Rangappa, Kanchugarakoppal S. 分享 收藏 Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinoma in Vitro and in VivoKeerthy, Hosadurga Kumar; Mohan, Chakrabhavi Dhananjaya; Siveen, Kodappully Sivaraman; Fuchs, Julian E.; Rangappa, Shobith; Sundaram, Mahalingam S.; Li, Feng; Girish, Kesturu S.; Sethi, Gautam; Basappa; Bender, Andreas; Rangappa, Kanchugarakoppal Subbegowda 分享 收藏 Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivoSethi, Gautam; Chatterjee, Snehajyoti; Rajendran, Peramaiyan; Li, Feng; Shanmugam, Muthu K.; Wong, Kwong Fai; Kumar, Alan Prem; Senapati, Parijat; Behera, Amit K.; Hui, Kam Man; Basha, Jeelan; Natesh, Nagashayana; Luk, John M.; Kundu, Tapas K. 分享 收藏 分享 收藏 Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinomaSubramaniam, Aruljothi; Shanmugam, Muthu K.; Perumal, Ekambaram; Li, Feng; Nachiyappan, Alamelu; Dai, Xiaoyun; Swamy, Shivananju Nanjunda; Ahn, Kwang Seok; Kumar, Alan Prem; Tan, Benny K. H.; Hui, Kam Man; Sethi, Gautam 分享 收藏 Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4Manu, Kanjoormana Aryan; Shanmugam, Muthu K.; Rajendran, Peramaiyan; Li, Feng; Ramachandran, Lalitha; Hay, Hui Sin; Kannaiyan, Radhamani; Swamy, Shivananju Nanjunda; Vali, Shireen; Kapoor, Shweta; Ramesh, Bhargavi; Bist, Pradeep; Koay, Evelyn S.; Lim, Lina H. K.; Ahn, Kwang Seok; Kumar, Alan Prem; Sethi, Gautam 分享 收藏 分享 收藏 分享 收藏 Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cellsChua, Angeline Wei Ling; Hay, Hui Sin; Rajendran, Peramaiyan; Shanmugam, Muthu K.; Li, Feng; Bist, Pradeep; Koay, Evelyn S. C.; Lim, Lina H. K.; Kumar, Alan Prem; Sethi, Gautam 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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