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D

Dachuan Huang

lymphoma translational research laboratory
H指数:27
被引数:5,502

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Preclinical activity of brincidofovir in peripheral T-cell and NK/T-cell lymphoma

Brincidofovir在周围T细胞和NK/T细胞淋巴瘤中的临床前活性

BMC Medicine
IF8.3
2026-02-060
OAAI
Jason Yongsheng Chan; Elizabeth Chun Yong Lee; Kelila Xin Ye Chai; Boon Yee Lim; Zhimei Li; Jing Yi Lee; Bavani Kannan; Hui Yi Tay; Tun Kiat Ko; Jessica Sook-Ting Kok; Kah Suan Lim; Nur Ayuni Binte Muhammad Taib; Dachuan Huang; Jing Quan Lim; Masatoshi Hazama; Koji Fukushima; Bin Tean Teh; Soon Thye Lim; Choon Kiat Ong
Therapeutic Repurposing of Brincidofovir in Non-Hodgkin Lymphoma- Potential Synergy with Immune Checkpoint Blockade

非霍奇金淋巴瘤中布马那韦的治疗重定位——与免疫检查点阻断的潜在协同作用

BLOOD
IF23.1
2024-11-050
PRE
Chan, Jason Yongsheng; Lee, Elizabeth Chun Yong; Chai, Kelila Xin Ye; Lim, Boon Yee; Li, Zhimei; Lee, Jing Yi; Kannan, Bavani; Ko, Tun Kiat; Kok, Jessica Sook-Ting; Lim, Kah Suan; Taib, Nur Ayuni Muhammad; Huang, Dachuan; Lim, Jing Quan; Hazama, Masatoshi; Fukushima, Koji; Teh, Bin Tean; Lim, Soon Thye; Ong, Choon Kiat
CDK4/6 inhibition augments anti-tumor efficacy of XPO1 inhibitor selinexor in natural killer/T-cell lymphoma

CDK4/6抑制增强XPO1抑制剂selinexor在自然杀伤/T细胞淋巴瘤中的抗肿瘤功效

CANCER LETTERS
IF10.1
2024-08-010
OA
Wang, Yali; Chen, Jianfeng; Gao, Yan; Chai, Kelila Xin Ye; Hong, Jing Han; Wang, Peili; Chen, Jinghong; Yu, Zhaoliang; Liu, Lizhen; Huang, Cheng; Taib, Nur Ayuni Muhammad; Lim, Kerry May Huifen; Guan, Peiyong; Chan, Jason Yongsheng; Huang, Dachuan; Teh, Bin Tean; Li, Wenyu; Lim, Soon Thye; Yu, Qiang; Ong, Choon Kiat; Huang, Huiqiang; Tan, Jing
Potent anti-proliferative activity of brincidofovir in Diffuse Large B-cell Lymphoma with overexpression of transcriptional repressor TLE1
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Lee, Jing Yi; Ko, Tun Kiat; Lee, Elizabeth Chun Yong; Kannan, Bavani; Lim, Boon Yee; Li, Zhimei; Guo, Zexi; Loh, Jui Wan; Ng, Cedric Chuan-Young; Chai, Kelila Xin Ye; Taib, Nur Ayuni Binte Muhammad; Lim, Kerry; Huang, Dachuan; Lim, Jing Quan; Hazama, Masatoshi; Fukushima, Koji; Bin Tean Teh; Soon Thye Lim; Choon Kiat Ong; Chan, Jason Yongsheng
Single-Cell Analysis Reveals Malignant Cells Reshape the Cellular Landscape and Foster an Immunosuppressive Microenvironment of Extranodal NK/T-Cell Lymphoma

单细胞分析揭示恶性细胞重塑细胞景观并促进结外NK/T细胞淋巴瘤的免疫抑制微环境

ADVANCED SCIENCE
IF14.1
2023-11-104
OA
Li, Yi-Qi; Luo, Chun-Ling; Jiang, Jia-Xin; He, Shuai; Liu, Yang; Yan, Wen-Xin; Xia, Yi; Cui, Qian; Huang, Ying; Lim, Jing Quan; Huang, Dachuan; Hussein, Izzah Nabilah; Gao, Yan; Lin, Guo-Wang; Ling, Yi-Hong; Ma, Dong; Zhang, Yue-Tong; Chan, Jason Yongsheng; Wei, Pan-Pan; Wang, Xiao-Xiao; Cheng, Chee Leong; Xiong, Jie; Zhao, Wei-Li; Ong, Choon Kiat; Lim, Soon Thye; Huang, Hui-Qiang; Peng, Rou-Jun; Bei, Jin-Xin
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma

PBRM1-deficient PBAF复合物靶向异常基因组位点以激活透明细胞肾细胞癌中的nf-κb途径

NATURE CELL BIOLOGY
IF19.1
2023-04-247
PRE
Yao, Xiaosai; Hong, Jing Han; Nargund, Amrita M.; Ng, Michelle Shu Wen; Heng, Hong Lee; Li, Zhimei; Guan, Peiyong; Sugiura, Masahiro; Chu, Pek Lim; Wang, Loo Chien; Ye, Xiaofen; Qu, James; Kwek, Xiu Yi; Lim, Jeffrey Chun Tatt; Ooi, Wen Fong; Koh, Joanna; Wang, Zhenxun; Pan, You-Fu; Ong, Yan Shan; Tan, Kiat-Yi; Goh, Jian Yuan; Ng, Sheng Rong; Pignata, Luca; Huang, Dachuan; Lezhava, Alexander; Tay, Su Ting; Lee, Minghui; Yeo, Xun Hui; Tam, Wai Leong; Rha, Sun Young; Li, Shang; Guccione, Ernesto; Futreal, Andrew; Tan, Jing; Yeong, Joe Poh Sheng; Hong, Wanjin; Yauch, Robert; Chang, Kenneth Tou-En; Sobota, Radoslaw M.; Tan, Patrick; Teh, Bin Tean
Single cell landscape of multicentric Castleman disease in identical twins
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Chan, Jason Yongsheng; Loh, Jui Wan; Lim, Jing Quan; Liany, Herty; Lee, Elizabeth Chun Yong; Lee, Jing Yi; Kannan, Bavani; Lim, Boon Yee; Lim, Kerry; Ha, Jeslin Chian Hung; Ng, Cedric Chuan-Young; Ko, Tun Kiat; Huang, Dachuan; Seow, Dominique Yuan Bin; Cheng, Chee Leong; Chan, Sock Hoai; Ngeow, Joanne; Teh, Bin Tean; Lim, Soon Thye; Ong, Choon Kiat
Aberrant JAK-STAT signaling-mediated chromatin remodeling impairs the sensitivity of NK/T-cell lymphoma to chidamide
CLINICAL EPIGENETICS
IF4.4
2023-02-0610
OAAI
Chen, Jinghong; Zuo, Zhixiang; Gao, Yan; Yao, Xiaosai; Guan, Peiyong; Wang, Yali; Li, Zhimei; Liu, Zhilong; Hong, Jing Han; Deng, Peng; Chan, Jason Yongsheng; Cheah, Daryl Ming Zhe; Lim, Jingquan; Chai, Kelila Xin Ye; Chia, Burton Kuan Hui; Pang, Jane Wan Lu; Koh, Joanna; Huang, Dachuan; He, Haixia; Sun, Yichen; Liu, Lizhen; Liu, Shini; Huang, Yuhua; Wang, Xiaoxiao; You, Hua; Saraf, Sahil Ajit; Grigoropoulos, Nicholas Francis; Li, Xiaoqiu; Bei, Jinxin; Kang, Tiebang; Lim, Soon Thye; Teh, Bin Tean; Huang, Huiqiang; Ong, Choon Kiat; Tan, Jing
An ex vivo platform to guide drug combination treatment in relapsed/refractory lymphoma
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-10-1916
PRE
Goh, Jasmine; De Mel, Sanjay; Hoppe, Michal M.; Rashid, Masturah Bte Mohd Abdul; Zhang, Xi Yun; Jaynes, Patrick; Ng, Esther Ka Yan; Rahmat, Nur'Atiqa Diana Binti; Jayalakshmi; Liu, Clementine Xin; Poon, Limei; Chan, Esther; Lee, Joanne; Chee, Yen Lin; Koh, Liang Piu; Tan, Lip Kun; Soh, Teck Guan; Yuen, Yi Ching; Loi, Hoi-Yin; Ng, Siok-Bian; Goh, Xueying; Eu, Donovan; Loh, Stanley; Ng, Sheldon; Tan, Daryl; Cheah, Daryl Ming Zhe; Pang, Wan Lu; Huang, Dachuan; Ong, Shin Yeu; Nagarajan, Chandramouli; Chan, Jason Yongsheng; Ha, Jeslin Chian Hung; Khoo, Lay Poh; Somasundaram, Nagavalli; Tang, Tiffany; Ong, Choon Kiat; Chng, Wee-Joo; Lim, Soon Thye; Chow, Edward K.; Jeyasekharan, Anand D.
A genomic-augmented multivariate prognostic model for the survival of natural-killer/T-cell lymphoma patients from an international cohort
AMERICAN JOURNAL OF HEMATOLOGY
IF9.9
2022-07-056
OAAI
Lim, Jing Quan; Huang, Dachuan; Chan, Jason Yongsheng; Laurensia, Yurike; Wong, Esther Kam Yin; Cheah, Daryl Ming Zhe; Chia, Burton Kuan Hui; Chuang, Wen-Yu; Kuo, Ming-Chung; Su, Yi-Jiun; Cai, Qing-qing; Feng, Yanfen; Rao, Huilan; Feng, Li-Na; Wei, Pan-Pan; Chen, Jie-Rong; Han, Bo-Wei; Lin, Guo-Wang; Cai, Jun; Fang, Yu; Tan, Jing; Hong, Huangming; Liu, Yanhui; Zhang, Fen; Li, Wenyu; Poon, Michelle L. M.; Ng, Siok-Bian; Jeyasekharan, Anand; Ha, Jeslin Chian Hung; Khoo, Lay Poh; Chin, Suk Teng; Pang, Wan Lu; Kee, Rebecca; Cheng, Chee Leong; Grigoropoulos, Nicholas Francis; Tang, Tiffany; Tao, Miriam; Farid, Mohamad; Puan, Kia Joo; Xiong, Jie; Zhao, Wei-Li; Khor, Chiea Chuen; Hwang, William; Kim, Won Seog; Campo, Elias; Tan, Patrick; Teh, Bin Tean; Chng, Wee-Joo; Rotzschke, Olaf; Tousseyn, Thomas; Huang, Hui-Qiang; Rozen, Steve; Lim, Soon Thye; Shih, Lee-Yung; Bei, Jin-Xin; Ong, Choon Kiat
CREBBP cooperates with the cell cycle machinery to attenuate chidamide sensitivity in relapsed/refractory diffuse large B-cell lymphoma
CANCER LETTERS
IF10.1
2021-11-0113
OAAI
Sun, Yichen; Gao, Yan; Chen, Jianfeng; Huang, Ling; Deng, Peng; Chen, Jinghong; Chai, Kelila Xin Ye; Hong, Jing Han; Chan, Jason Yongsheng; He, Haixia; Wang, Yali; Cheah, Daryl; Lim, Jing Quan; Chia, Burton Kuan Hui; Huang, Dachuan; Liu, Lizhen; Liu, Shini; Wang, Xiaoxiao; Teng, Yan; Pang, Diwen; Grigoropoulos, Nicholas Francis; Teh, Bin Tean; Yu, Qiang; Lim, Soon Thye; Li, Wenyu; Ong, Choon Kiat; Huang, Huiqiang; Tan, Jing
DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes
MOLECULAR CANCER
IF33.9
2021-10-169
OAAI
Kizhakeyil, Atish; Zaini, Nurmahirah Binte Mohammed; Poh, Zhi Sheng; Wong, Brandon Han Siang; Loh, Xinpeng; Ng, Aik Seng; Low, Zun Siong; Prasannan, Praseetha; Gong, Chun; Tan, Michelle Guet Khim; Nagarajan, Chandramouli; Huang, Dachuan; Lu, Pang Wan; Lim, Jing Quan; Barrans, Sharon; Ong, Choon Kiat; Lim, Soon Thye; Chng, Wee Joo; Follows, George; Hodson, Daniel J.; Du, Ming Qing; Goh, Yeow Tee; Tan, Suat Hoon; Grigoropoulos, Nicholas Francis; Verma, Navin Kumar
Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma (vol 34, 3413, 2020)
LEUKEMIA
IF13.4
2021-03-080
OAAI
Lim, Jing Quan; Huang, Dachuan; Tang, Tiffany; Tan, Daryl; Laurensia, Yurike; Peng, Rou-Jun; Wong, Esther Kam Yin; Cheah, Daryl Ming Zhe; Chia, Burton Kuan Hui; Iqbal, Jabed; Grigoropoulos, Nicholas Francis; Nairismagi, Maarja-Liisa; Ng, Cedric Chuan Young; Rajasegaran, Vikneswari; Hong, Huangming; Kim, Seok Jin; Cho, Junhun; Tse, Eric; Mow, Benjamin; Cai, Qi-Chun; Poon, Li-Mei; Cai, Qing-qing; Tan, Jing; Chan, Jason Yongsheng; Lim, Johnathan Xiande; Goh, Yeow Tee; Phipps, Colin; Rotzschke, Olaf; Cheng, Chee Leong; Ha, Jeslin Chian Hung; Khoo, Lay Poh; Loh, Yvonne Su Ming; Au-Yeung, Rex; Chan, Thomas Sau-Yan; Kwong, Yok-Lam; Hwang, William; Kim, Won Seog; Bei, Jin-Xin; Lin, Tongyu; Ong, Choon Kiat; Lim, Soon Thye
No association between ECSIT germline mutations and hemophagocytic lymphohistiocytosis in natural killer/T-cell lymphoma
HAEMATOLOGICA
IF7.9
2020-10-131
OAAI
Ong, Shin Yeu; Lim, Jing Quan; Grigoropoulos, Nicholas; Laurensia, Yurike; Huang, Dachuan; Chia, Burton Kuan Hui; Zhe, Daryl Cheah Ming; Saraf, Sahil Ajit; Cheng, Chee Leong; Chuang, Wen-Yu; Kuo, Ming-Chung; Su, Yi-Jiun; Phipps, Colin; Nagarajan, Chandramouli; Lee, Yuh Shan; Lung, Daryl Tan Chen; Shih, Lee-Yung; Goh, Yeow Tee; Lim, Soon Thye; Ong, Choon Kiat
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-10-0564
OA
Chan, Jason Yongsheng; Lim, Jing Quan; Yeong, Joe; Ravi, Vinod; Guan, Peiyong; Boot, Arnoud; Tay, Timothy Kwang Yong; Selvarajan, Sathiyamoorthy; Nasir, Nur Diyana; Loh, Jie Hua; Ong, Choon Kiat; Huang, Dachuan; Tan, Jing; Li, Zhimei; Ng, Cedric Chuan-Young; Thuan Tong Tan; Masuzawa, Mikio; Sung, Ken Wing-Kin; Farid, Mohamad; Quek, Richard Hong Hui; Tan, Ngian Chye; Teo, Melissa Ching Ching; Rozen, Steven George; Tan, Patrick; Futreal, Andrew; Teh, Bin Tean; Soo, Khee Chee
Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma
LEUKEMIA
IF13.4
2020-08-0560
OAAI
Lim, Jing Quan; Huang, Dachuan; Tang, Tiffany; Tan, Daryl; Laurensia, Yurike; Peng, Rou-Ju; Wong, Esther Kam Yin; Cheah, Daryl Ming Zhe; Chia, Burton Kuan Hui; Iqbal, Jabed; Grigoropoulos, Nicholas Francis; Nairismagi, Maarja-Liisa; Ng, Cedric Chuan Young; Rajasegaran, Vikneswari; Hong, Huangming; Kim, Seok Jin; Cho, Junhun; Tse, Eric; Mow, Benjamin; Cai, Qi-Chun; Poon, Li-Mei; Cai, Qing-qing; Tan, Jing; Chan, Jason Yongsheng; Lim, Johnathan Xiande; Goh, Yeow Tee; Phipps, Colin; Rotzschke, Olaf; Cheng, Chee Leong; Ha, Jeslin Chian Hung; Khoo, Lay Poh; Loh, Yvonne Su Ming; Au-Yeung, Rex; Chan, Thomas Sau-Yan; Kwong, Yok-Lam; Hwang, William; Kim, Won Seog; Bei, Jin-Xin; Lin, Tongyu; Ong, Choon Kiat; Lim, Soon Thye

研究方向

暂未获取到该数据
C
Choon Kiat Ong
H 指数:62论文数:435被引数:2.5万
B
Bin Tean Teh
H 指数:113论文数:1,104被引数:5.3万
S
Soon Thye Lim
H 指数:46论文数:381被引数:8,141
J
Jing Quan Lim
H 指数:26论文数:117被引数:3,995
J
Jason Yongsheng Chan
H 指数:28论文数:254被引数:2,807
谭静 封面图
谭静
H 指数:38论文数:163被引数:6,838
P
Patrick Tan
H 指数:108论文数:1,022被引数:4.7万
B
Burton Kuan Hui Chia
H 指数:20论文数:46被引数:2,284
C
Cedric Chuan Young Ng
H 指数:28论文数:137被引数:5,480
P
P. Andrew Futreal
H 指数:159论文数:1,352被引数:16.5万