Tsai‐Kun Li - Publications, H-index & Citations

Tsai‐Kun Li

national taiwan university

42H指数

130论文数

6.4K被引数

收录论文 53

发表时间

TOP2 and NOS2 Orchestrate the Generation of DNA Breaks to Promote Colitis Cancer Initiation TOP2和NOS2协同调控DNA断裂的产生以促进结肠炎相关癌症的起始

Cancers

IF4.4

2026-05-09

OAAI

Ting-Kang Chang; Shiu-Ling Li; Anne-Cécile Brunac; Jia-Jun Huang; Yen-Hsiu Yeh; Pierre Brousset; Jean-Marc Egly; Tsai-Kun Li

Development of Liposomal Formulations for 1,4-Bis-L/L Methionine-Conjugated Mitoxantrone–Amino Acid Conjugates to Improve Pharmacokinetics and Therapeutic Efficacy 脂质体制剂的开发：用于1,4-双-L/L-蛋氨酸缀合的米托蒽醌-氨基酸缀合物，以改善药代动力学和治疗效能

Pharmaceutics

IF5.5

2026-03-03

OAAI

Ting-Lun Yang; Tsai-Kun Li; Chin-Tin Chen

Promoters of ASCL1-and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells

EMBO MOLECULAR MEDICINE

IF8.3

2022-03-09

OAAI

Costanzo, Federico; Martinez Diez, Marta; Santamaria Nunez, Gema; Ignacio Diaz-Hernandez, Juan; Genes Robles, Carlos Mario; Diez Perez, Javier; Compe, Emmanuel; Ricci, Romeo; Li, Tsai-Kun; Coin, Frederic; Martinez Leal, Juan Fernando; Maria Garrido-Martin, Eva; Egly, Jean Marc

Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicity

MOLECULAR AND CELLULAR BIOCHEMISTRY

IF3.7

2022-01-28

PREAI

Yeh, Yen-Hsiu; Tsai, Chia-Chih; Chen, Tien-Wen; Lee, Chieh-Hua; Chang, Wei-Jer; Hsieh, Mei-Yi; Li, Tsai-Kun

RETRACTION: Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases (Retraction of Vol 190, art no 112074, 2020)

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-08-01

PREAI

Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; Li, Tsai-Kun; Lee, Sung-Bau; Lin, Mei-Hsiang

The role of extracellular vesicles in prostate cancer with clinical applications

ENDOCRINE-RELATED CANCER

IF4.6

2020-05-01

OAAI

Tai, Yu-Ling; Lin, Chun-Jung; Li, Tsai-Kun; Shen, Tang-Long; Hsieh, Jer-Tsong; Chen, Benjamin P. C.

RETRACTED: Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases (Retracted Article)

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-03-01

PREAI

Lee, Jiann-Fong; Chang, Ting Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; Li, Tsai-Kun; Lee, Sung-Bau; Lin, Mei-Hsiang

The paracrine induction of prostate cancer progression by caveolin-1

CELL DEATH & DISEASE

IF9.6

2019-11-04

OAAI

Lin, Chun-Jung; Yun, Eun-Jin; Lo, U-Ging; Tai, Yu-Ling; Deng, Su; Hernandez, Elizabeth; Dang, Andrew; Chen, Yu-An; Saha, Debabrata; Mu, Ping; Lin, Ho; Li, Tsai-Kun; Shen, Tang-Long; Lai, Chih-Ho; Hsieh, Jer-Tsong

Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway 炎性干扰素通过PI3K/AKT/mTOR通路激活hif-1α 介导的上皮间质转化

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2018-03-27

OAAI

Yeh, Yen-Hsiu; Hsiao, Ho-Fu; Yeh, Yen-Cheng; Chen, Tien-Wen; Li, Tsai-Kun

Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry (vol 45, pg 10861, 2017)

NUCLEIC ACIDS RESEARCH

IF13.1

2017-09-04

OAAI

Wang, Ying-Ren; Chen, Shin-Fu; Wu, Chyuan-Chuan; Liao, Yi-Wen; Lin, Te-Sheng; Liu, Ko-Ting; Chen, Yi-Song; Li, Tsai-Kun; Chien, Tun-Cheng; Chan, Nei-Li

Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry

NUCLEIC ACIDS RESEARCH

IF13.1

2017-08-24

OAAI

Wang, Ying-Ren; Chen, Shin-Fu; Wu, Chyuan-Chuan; Liao, Yi-Wen; Lin, Te-Sheng; Liu, Ko-Ting; Chen, Yi-Song; Li, Tsai-Kun; Chien, Tun-Cheng; Chan, Nei-Li

microRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2017-04-10

PREAI

Lin, Han-Chen; Liu, Shin-Yun; Yen, Er-Yen; Li, Tsai-Kun; Lai, I-Rue

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

CANCER LETTERS

IF10.1

2017-03-01

PREAI

Chien, Ming-Hsien; Lee, Tzong-Huei; Lee, Wei-Jiunn; Yeh, Yen-Hsiu; Li, Tsai-Kun; Wang, Po-Chuan; Chen, Jih-Jung; Chow, Jyh-Ming; Lin, Yung-Wei; Hsiao, Michael; Wang, Shih-Wei; Hua, Kuo-Tai

Rhapontigenin inhibits TGF-β-mediated epithelial-mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation

ONCOLOGY REPORTS

IF3.9

2016-03-09

OAAI

Yeh, Yen-Hsiu; Wang, Shih-Wei; Yeh, Yen-Cheng; Hsiao, Ho-Fu; Li, Tsai-Kun

Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2014-11-28

OAAI

Hsieh, Meng-Hsun; Tsai, Cheng-Hui; Lin, Chuan-Chuan; Li, Tsai-Kun; Hung, Ting-Wei; Chang, Li-Te; Hsin, Ling-Wei; Teng, Shu-Chun

Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells

PHYTOMEDICINE

IF8.3

2014-10-01

PREAI

Chou, Shang-Min; Lai, Wan-Jung; Hong, Tzu-Wen; Lai, Jui-Ya; Tsai, Sheng-Hong; Chen, Yen-Hsun; Yu, Sz-Hsien; Kao, Cheng-Hsiang; Chu, Richard; Ding, Shih-Torng; Li, Tsai-Kun; Shen, Tang-Long

On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs

NUCLEIC ACIDS RESEARCH

IF13.1

2013-09-14

164

OAAI

Wu, Chyuan-Chuan; Li, Yi-Ching; Wang, Ying-Ren; Li, Tsai-Kun; Chan, Nei-Li

DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2013-05-16

OAAI

Lin, Bo-Chi; Su, Li-Hsin; Weng, Shih-Che; Pan, Yu-Jiao; Chan, Nei-Li; Li, Tsai-Kun; Wang, Hsin-Chih; Sun, Chin-Hung

Topoisomerase II-Mediated DNA Cleavage and Mutagenesis Activated by Nitric Oxide Underlie the Inflammation-Associated Tumorigenesis

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2013-04-01

PREAI

Yang, Yu-Chen; Chou, Han-Yi E.; Shen, Tang-Long; Chang, Wei-Jer; Tai, Pei-Han; Li, Tsai-Kun

Docosahexaenoic acid suppresses the expression of FoxO and its target genes

JOURNAL OF NUTRITIONAL BIOCHEMISTRY

IF4.9

2012-12-01

OAAI

Chen, Yu-Jen; Chen, Chih-Chien; Li, Tsai-Kun; Wang, Pei-Hwa; Liu, Li-Ru; Chang, Fang-Ying; Wang, Ya-Chin; Yu, Yu-Hsiang; Lin, Shau-Ping; Mersmann, Harry J.; Ding, Shih-Torng

研究方向