Minjun Chen - Publications, H-index & Citations

Minjun Chen

national center for toxicological research

43H指数

170论文数

5.6K被引数

收录论文 63

发表时间

Serum Hepatocyte Growth Factor Predicts Outcomes in Non-Acetaminophen Drug-Induced Acute Liver Failure 血清肝细胞生长因子预测非对乙酰氨基酚药物诱导的急性肝衰竭的结局

Liver International

IF5.2

2026-10-01

OAAI

Tao Wang; Silvia M. Bacot; Kamai Patterson; Devira Friedman; Caroline Taylor; Huixiao Hong; Jie Liu; Mark I. Avigan; Paul Hayashi; Jody A. Rule; William M. Lee; Jorge Rakela; Gerald M. Feldman; Minjun Chen

DILIrank 2.0: An updated and expanded database for drug-induced liver injury risk based on FDA labeling and a literature review DILIrank 2.0：一个基于FDA标签和文献综述的药物诱导性肝损伤风险更新并扩展的数据库

Drug Discovery Today

IF7.5

2025-09-24

PREAI

AyoOluwa O. Olubamiwa; Yanyan Qu; Skylar Connor; Weida Tong; Dongying Li; Minjun Chen

New approach methodologies (NAMs) for drug-induced liver injury (DILI): Where are we now?药物诱导性肝损伤（DILI）的新方法学（NAMs）：我们现在处于什么阶段？

Drug Discovery Today

IF7.5

2025-08-11

OAAI

Shivangi Shrimali; Minjun Chen; Dongying Li; Weida Tong

Evaluation of the role of comedication properties in the severity of drug-induced liver injury using machine learning techniques 使用机器学习技术研究合并用药特性在药物性肝损伤严重程度中的作用评估

Expert Opinion on Drug Metabolism & Toxicology

IF3.4

2025-07-06

PREAI

Irene Victoria Bermúdez-Pérez; Ismael Alvarez-Alvarez; Inmaculada Medina-Cáliz; Mercedes Robles-Diaz; Hao Niu; Minjun Chen; Raúl J. Andrade; Mª Isabel Lucena; Camilla Stephens; Andrés Gonzalez-Jimenez

Drug metabolizing enzymes and transporters, and their roles for the development of drug-induced liver injury 药物代谢酶和转运体，以及它们在药物诱导性肝损伤发展中的作用

Expert Opinion on Drug Metabolism & Toxicology

IF3.4

2025-06-09

PREAI

AyoOluwa O. Olubamiwa; Jingyi Ma; Patrice Dehanne; Catherine Noban; Yeliz Angın; Olivier Barberan; Minjun Chen

Artificial Intelligence: An Emerging Tool for Studying Drug-Induced Liver Injury 人工智能: 研究药物性肝损伤的新兴工具

LIVER INTERNATIONAL

IF5.2

2025-02-21

OAAI

Niu, Hao; Alvarez-Alvarez, Ismael; Chen, Minjun

Genetic Variants of GBP4: Reduced Risks for Drug-Induced Acute Liver Failure in Non-Finnish European Population GBP4的遗传变异: 降低非芬兰欧洲人群药物诱导的急性肝衰竭的风险

LIVER INTERNATIONAL

IF5.2

2025-01-27

PREAI

Liao, Tsung-Jen; Xia, Menghang; Hayashi, Paul; Pan, Bohun; Aithal, Guruprasad P.; Lucena, M. Isabel; Andrade, Raul J.; Rule, Jody A.; Lee, William M.; Rakela, Jorge; Huang, Ruili; Chen, Minjun

Physiological liver microtissue 384-well microplate system for preclinical hepatotoxicity assessment of therapeutic small molecule drugs 用于治疗性小分子药物临床前肝毒性评估的生理性肝微组织384微孔板系统

TOXICOLOGICAL SCIENCES

IF4.1

2024-10-14

OAAI

Fas, Lola; Chen, Minjun; Tong, Weida; Wenz, Friederike; Hewitt, Nicola J.; Tu, Monika; Sanchez, Katarzyna; Zapiorkowska-Blumer, Natalia; Varga, Hajnalka; Kaczmarska, Karolina; Colombo, Maria Vittoria; Filippi, Bruno G. H.

Drug interaction with Udp-Glucuronosyltransferase (UGT) enzymes is a predictor of drug-induced liver injury

HEPATOLOGY

IF15.8

2024-07-17

PREAI

Olubamiwa, AyoOluwa O.; Liao, Tsung-Jen; Zhao, Jinwen; Dehanne, Patrice; Noban, Catherine; Angin, Yeliz; Barberan, Olivier; Chen, Minjun

Automatic text classification of drug-induced liver injury using document-term matrix and XGBoost

FRONTIERS IN ARTIFICIAL INTELLIGENCE

IF4.7

2024-06-03

OAAI

Chen, Minjun; Wu, Yue; Wingerd, Byron; Liu, Zhichao; Xu, Joshua; Thakkar, Shraddha; Pedersen, Thomas J.; Donnelly, Tom; Mann, Nicholas; Tong, Weida; Wolfinger, Russell D.; Bao, Wenjun

Machine Learning to Predict Drug-Induced Liver Injury and Its Validation on Failed Drug Candidates in Development 机器学习预测药物性肝损伤及其对研发失败候选药物的验证

TOXICS

IF4.1

2024-05-24

OAAI

Mostafa, Fahad; Howle, Victoria; Chen, Minjun

Medical device report analyses from MAUDE: Device and patient outcomes, adverse events, and sex-based differential effects

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2024-05-01

PREAI

Liao, Tsung-Jen; Crosby, Lynn; Cross, Kevin; Chen, Minjun; Elespuru, Rosalie

Composite Plot for Visualizing Aminotransferase and Bilirubin Changes in Clinical Trials of Subjects with Abnormal Baseline Values

DRUG SAFETY

IF3.8

2024-04-20

OAAI

Tesfaldet, Bereket; Patel, Tejas; Chen, Minjun; Pucino, Frank; Rosario, Lilliam; Hayashi, Paul; Almario, Eileen Navarro

Computational models for predicting liver toxicity in the deep learning era

FRONTIERS IN TOXICOLOGY

IF4.6

2024-01-19

OAAI

Mostafa, Fahad; Chen, Minjun

In silico modeling-based new alternative methods to predict drug and herb-induced liver injury: A review

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2023-09-01

OAAI

Shin, Hyun Kil; Huang, Ruili; Chen, Minjun

Whole Exome Sequencing Reveals Genetic Variants in HLA Class II Genes Associated With Transplant-free Survival of Indeterminate Acute Liver Failure

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY

IF3

2022-06-02

OAAI

Liao, Tsung-Jen; Pan, Bohu; Hong, Huixiao; Hayashi, Paul; Rule, Jody A.; Ganger, Daniel; Lee, William M.; Rakela, Jorge; Chen, Minjun

Integrative approaches for studying the role of noncoding RNAs in influencing drug efficacy and toxicity

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2022-03-30

OAAI

Li, Dongying; Chen, Minjun; Hong, Huixiao; Tong, Weida; Ning, Baitang

A systematic comparison of hepatobiliary adverse drug reactions in FDA and EMA drug labeling reveals discrepancies FDA和EMA药物标签中肝胆不良药物反应的系统比较揭示了差异

DRUG DISCOVERY TODAY

IF7.5

2022-01-01

PREAI

Wu, Yue; Xiao, Wenzhong; Tong, Weida; Borlak, Juergen; Chen, Minjun

BERT-Based Natural Language Processing of Drug Labeling Documents: A Case Study for Classifying Drug-Induced Liver Injury Risk

FRONTIERS IN ARTIFICIAL INTELLIGENCE

IF4.7

2021-12-06

OAAI

Wu, Yue; Liu, Zhichao; Wu, Leihong; Chen, Minjun; Tong, Weida

Elevated bilirubin, alkaline phosphatase at onset, and drug metabolism are associated with prolonged recovery from DILI

JOURNAL OF HEPATOLOGY

IF33

2021-08-01

OAAI

Ashby, Kristin; Zhuang, Wei; Gonzalez-Jimenez, Andres; Alvarez-Alvarez, Ismael; Isabel Lucena, M.; Andrade, Raul J.; Aithal, Guruprasad P.; Suzuki, Ayako; Chen, Minjun

研究方向