Paul J. Smith - Publications, H-index & Citations

Paul J. Smith

AstraZeneca

43H指数

342论文数

7.4K被引数

收录论文 50

发表时间

Hypoxia signaling: Challenges and opportunities for cancer therapy

SEMINARS IN CANCER BIOLOGY

IF15.7

2022-10-01

OAAI

Ivan, Mircea; Fishel, Melissa L.; Tudoran, Oana M.; Pollok, Karen E.; Wu, Xue; Smith, Paul J.

Targeting DNA topoisomerase IIα (TOP2A) in the hypoxic tumour microenvironment using unidirectional hypoxia-activated prodrugs (uHAPs)

IUBMB LIFE

IF3.2

2022-05-02

OAAI

Smith, Paul J.; McKeown, Stephanie R.; Patterson, Laurence H.

Pitfalls in conducting prospective trials in stage III cardiac amyloidosis - experience from the REVEAL study

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2017-10-06

OAAI

Phillips, Elizabeth H.; Nash, Stephen; Adedayo, Toyin; Whelan, Carol J.; Fontana, Marianna; Mahmood, Shameem; Lachmann, Helen J.; Gillmore, Julian D.; Smith, Paul; Clifton-Hadley, Laura; Hawkins, Philip N.; Wechalekar, Ashutosh D.

EdU and BrdU incorporation resolve their differences

CELL CYCLE

IF3.4

2016-05-13

OAAI

Smith, Paul J.

Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance

CELL CYCLE

IF3.4

2014-10-28

OAAI

Errington, Rachel J.; Brown, Martyn R.; Silvestre, Oscar F.; Njoh, Kerenza L.; Chappell, Sally C.; Khan, Imtiaz A.; Rees, Paul; Wilks, Steve P.; Smith, Paul J.; Summers, Huw D.

Mitotic bypass via an occult cell cycle phase following DNA topoisomerase II inhibition in p53 functional human tumor cells

CELL CYCLE

IF3.4

2014-10-28

OAAI

Smith, Paul J.; Marquez, Nuria; Wiltshire, Marie; Chappell, Sally; Njoh, Kerenza; Campbell, Lee; Khan, Imtiaz A.; Silvestre, Oscar; Errington, Rachel J.

ProgeniDB - A novel cell lineage database for generation associated phenotypic behavior in cell-based assays

CELL CYCLE

IF3.4

2014-10-28

OAAI

Khan, Imtiaz A.; Husemann, Peter; Campbell, Lee; White, Nick S.; White, Richard J.; Smith, Paul J.; Errington, Rachel J.

Photo-oxidation of tyrosine in a bio-engineered bacterioferritin 'reaction centre'-A protein model for artificial photosynthesis

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2014-10-01

OAAI

Hingorani, Kastoori; Pace, Ron; Whitney, Spencer; Murray, James W.; Smith, Paul; Cheah, Mun Hon; Wydrzynski, Tom; Hillier, Warwick

Determination of the PS I content of PS II core preparations using selective emission: A new emission of PS II at 780 nm

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2014-01-01

OAAI

Morton, Jennifer; Hall, Jeremy; Smith, Paul; Akita, Fusamichi; Koua, Faisal Hammad Mekky; Shen, Jian-Ren; Krausz, Elmars

MAPK1 mutation E322K modulates ERK pathway output and feedback.

MOLECULAR CANCER THERAPEUTICS

IF5.5

2013-11-01

PREAI

Guan, Nin; Delpuech, Oona; Greenawalt, Danielle; Jacques, Kelly; Gharahdaghi, Farzin; Zinda, Michael; Smith, Paul J.; Guichard, Sylvie M.

Modeling Price Dynamics in eBay Auctions Using Differential Equations

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

IF3

2012-01-01

PREAI

Wang, Shanshan; Jank, Wolfgang; Shmueli, Galit; Smith, Paul

Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

IF4.8

2011-11-01

OAAI

Atari, M. I.; Chappell, M. J.; Errington, R. J.; Smith, P. J.; Evans, N. D.

Instability of ABCG2-associated side population expression in human A549 lung cancer cells and its contribution to drug resistance

CANCER RESEARCH

IF16.6

2011-04-01

PREAI

Cosentino, Laura; Wiltshire, Marie; Chappel, Sally; Burns, Phil; Patterson, Laurence H.; Pors, Klaus; Errington, Rachel J.; Smith, Paul J.

mTOR kinase inhibition relieves feedback inhibition of RTK and PI3K signaling in breast cancer cells

CANCER RESEARCH

IF16.6

2011-04-01

PREAI

Rodrik-Outmezguine, Vanessa S.; Chandarlapaty, Sarat; Cao, Nen; Smith, Paul; Guichard, Sylvie; Rosen, Neal

Statistical analysis of nanoparticle dosing in a dynamic cellular system

NATURE NANOTECHNOLOGY

IF34.9

2011-01-23

147

PREAI

Summers, Huw D.; Rees, Paul; Holton, Mark D.; Brown, M. Rowan; Chappell, Sally C.; Smith, Paul J.; Errington, Rachel J.

DUSP16 is an epigenetically regulated determinant of JNK signalling in Burkitt's lymphoma

BRITISH JOURNAL OF CANCER

IF6.8

2010-06-15

OAAI

Lee, S.; Syed, N.; Taylor, J.; Smith, P.; Griffin, B.; Baens, M.; Bai, M.; Bourantas, K.; Stebbing, J.; Naresh, K.; Nelson, M.; Tuthill, M.; Bower, M.; Hatzimichael, E.; Crook, T.

AZD8055 is an effective inhibitor of mTOR kinase signaling and breast cancer growth while relieving feedback inhibition of HER-kinase signaling

CANCER RESEARCH

IF16.6

2010-04-01

PREAI

Rodrik-Outmezguine, Vanessa S.; Cao, Nen; Chandarlapaty, Sarat; She, Qing-Bai; Ye, Qing; Smith, Paul; Guichard, Sylvie; Rosen, Neal

The Semiquinone-Iron Complex of Photosystem II: Structural Insights from ESR and Theoretical Simulation; Evidence that the Native Ligand to the Non-Heme Iron Is Carbonate

BIOPHYSICAL JOURNAL

IF3.1

2009-10-01

OAAI

Cox, Nicholas; Jin, Lu; Jaszewski, Adrian; Smith, Paul J.; Krausz, Elmars; Rutherford, A. William; Pace, Ron

Array-based DNA methylation profiling in follicular lymphoma 基于阵列的DNA甲基化分析在滤泡性淋巴瘤中的应用

LEUKEMIA

IF13.4

2009-07-09

OAAI

O'Riain, C.; O'Shea, D. M.; Yang, Y.; Le Dieu, R.; Gribben, J. G.; Summers, K.; Yeboah-Afari, J.; Bhaw-Rosun, L.; Fleischmann, C.; Mein, C. A.; Crook, T.; Smith, P.; Kelly, G.; Rosenwald, A.; Ott, G.; Campo, E.; Rimsza, L. M.; Smeland, E. B.; Chan, W. C.; Johnson, N.; Gascoyne, R. D.; Reimer, S.; Braziel, R. M.; Wright, G. W.; Staudt, L. M.; Lister, T. A.; Fitzgibbon, J.

The S1 split signal of photosystem II; a tyrosine-manganese coupled interaction

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2009-07-01

OAAI

Cox, Nicholas; Ho, Felix M.; Pewnim, Naray; Steffen, Ronald; Smith, Paul J.; Havelius, Kajsa G. V.; Hughes, Joseph L.; Debono, Lesley; Styring, Stenbjorn; Krausz, Elmars; Pace, Ron J.

研究方向