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Towards a more inductive world for drug repurposing approaches 走向一个更具诱导性的药物再利用方法世界 de la Fuente, Jesus; Serrano, Guillermo; Veleiro, Uxia; Casals, Mikel; Vera, Laura; Pizurica, Marija; Gomez-Cebrian, Nuria; Puchades-Carrasco, Leonor; Pineda-Lucena, Antonio; Vicent, Silve; Hernaez, Mikel 分享 收藏
G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1 Exposito, Francisco; Redrado, Miriam; Serrano, Diego; Calabuig-Farinas, Silvia; Bao-Caamano, Aida; Gallach, Sandra; Jantus-Lewintre, Eloisa; Diaz-Lagares, Angel; Rodriguez-Casanova, Aitor; Sandoval, Juan; San Jose-Eneriz, Edurne; Garcia, Javier; Redin, Esther; Senent, Yaiza; Leon, Sergio; Pio, Ruben; Lopez, Rafael; Oyarzabal, Julen; Pineda-Lucena, Antonio; Agirre, Xabier; Montuenga, Luis M.; Prosper, Felipe; Calvo, Alfonso 分享 收藏
Protein Biomarkers in Lung Cancer Screening: Technical Considerations and Feasibility Assessment Orive, Daniel; Echepare, Mirari; Bernasconi-Bisio, Franco; Fernandez Sanmamed, Miguel; Pineda-Lucena, Antonio; de la Calle-Arroyo, Carlos; Detterbeck, Frank; Hung, Rayjean J.; Johansson, Mattias; Robbins, Hilary A.; Seijo, Luis M.; Montuenga, Luis M.; Valencia, Karmele 分享 收藏
Epigenetic-based differentiation therapy for Acute Myeloid Leukemia San Jose-Eneriz, Edurne; Gimenez-Camino, Naroa; Rabal, Obdulia; Garate, Leire; Miranda, Estibaliz; Gomez-Echarte, Nahia; Garcia, Fernando; Charalampopoulou, Stella; Saez, Elena; Vilas-Zornoza, Amaia; San Martin-Uriz, Patxi; Valcarcel, Luis V.; Barrena, Naroa; Alignani, Diego; Tamariz-Amador, Luis Esteban; Perez-Ruiz, Ana; Hilscher, Sebastian; Schutkowski, Mike; Alfonso-Pierola, Ana; Martinez-Calle, Nicolas; Larrayoz, Maria Jose; Paiva, Bruno; Calasanz, Maria Jose; Munoz, Javier; Isasa, Marta; Martin-Subero, Jose Ignacio; Pineda-Lucena, Antonio; Oyarzabal, Julen; Agirre, Xabier; Prosper, Felipe 分享 收藏
Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer 靶向组蛋白乙酰化调控膀胱癌肿瘤微环境的研究 Nunes, Sandra P.; Morales, Lucia; Rubio, Carolina; Munera-Maravilla, Ester; Lodewijk, Iris; Suarez-Cabrera, Cristian; Martinez, Victor G.; Perez-Escavy, Mercedes; Perez-Crespo, Miriam; Sanchez, Miguel Alonso; Montesinos, Esther; San Jose-Eneriz, Edurne; Agirre, Xabier; Prosper, Felipe; Pineda-Lucena, Antonio; Henrique, Rui; Duenas, Marta; Correia, Margareta P.; Jeronimo, Carmen; Paramio, Jesus M. 分享 收藏
Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model Marlin, Elias; Valencia, Miguel; Peregrin, Nuria; Ferrero, Roberto; Nicolas, Maria Jesus; Vinueza-Gavilanes, Rodrigo; Pineda-Lucena, Antonio; Artieda, Julio; Arrasate, Montserrat; Aragon, Tomas 分享 收藏
AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity AG5是一种有效的非甾体抗炎和免疫调节剂，可保持先天免疫 Botella-Asuncion, Pablo; Rivero-Buceta, Eva M.; Vidaurre-Agut, Carla; Lama, Raquel; Rey-Campos, Magali; Moreno, Alejandro; Mendoza, Laura; Mingo-Casas, Patricia; Escribano-Romero, Estela; Gutierrez-Adan, Alfonso; Saiz, Juan Carlos; Smerdou, Cristian; Gonzalez, Gloria; Prosper, Felipe; Argemi, Josepmaria; San Miguel, Jesus; Sanchez-Cordon, Pedro J.; Figueras, Antonio; Quesada-Gomez, Jose Manuel; Novoa, Beatriz; Montoya, Maria; Martin-Acebes, Miguel A.; Pineda-Lucena, Antonio; Benlloch, Jose Maria 分享 收藏
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Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer Macaya, Irati; Roman, Marta; Welch, Connor; Entrialgo-Cadierno, Rodrigo; Salmon, Marina; Santos, Alba; Feliu, Iker; Kovalski, Joanna; Lopez, Ines; Rodriguez-Remirez, Maria; Palomino-Echeverria, Sara; Lonfgren, Shane M.; Ferrero, Macarena; Calabuig, Silvia; Ludwig, Iziar A.; Lara-Astiaso, David; Jantus-Lewintre, Eloisa; Guruceaga, Elizabeth; Narayanan, Shruthi; Ponz-Sarvise, Mariano; Pineda-Lucena, Antonio; Lecanda, Fernando; Ruggero, Davide; Khatri, Purvesh; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Ferrer, Irene; Paz-Ares, Luis; Drosten, Matthias; Barbacid, Mariano; Gil-Bazo, Ignacio; Vicent, Silve 分享 收藏
Identification and experimental validation of druggable epigenetic targets in hepatoblastoma Claveria-Cabello, Alex; Herranz, Jose Maria; Latasa, Maria Ujue; Arechederra, Maria; Uriarte, Iker; Pineda-Lucena, Antonio; Prosper, Felipe; Berraondo, Pedro; Alonso, Cristina; Sangro, Bruno; Marin, Jose Juan Garcia; Martinez-Chantar, Maria Luz; Ciordia, Sergio; Corrales, Fernando Jose; Francalanci, Paola; Alaggio, Rita; Zucman-Rossi, Jessica; Indersie, Emilie; Cairo, Stefano; Domingo-Sabat, Montserrat; Zanatto, Laura; Sancho-Bru, Pau; Armengol, Carolina; Berasain, Carmen; Fernandez-Barrena, Maite Garcia; Avila, Matias Antonio 分享 收藏
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Combined treatment with the epigenetic drug CM272 and an anti-BCL-XL proapoptotic drug sensitizes solid tumors to immune checkpoint blockade Senent, Yaiza; Fresquet, Vicente; Jimenez, Victoria; Valencia, Karmele; Remirez, Ana; Exposito, Francisco; Gonzalez-Huarriz, Marisol; de Cordoba, Borja Ruiz-Fernandez; Moreno, Haritz; Ajona, Daniel; Alonso, Marta M.; Lecanda, Fernando; Pineda-Lucena, Antonio; Prosper, Felipe; Calvo, Alfonso; Martinez-Climent, Jose Angel; Pio, Ruben 分享 收藏
IgG antibody response to pneumococcal-conjugated vaccine (Prevenar®13) in children with immunodeficiency disorders Garrido-Jareno, Marta; Miguel Sahuquillo-Arce, Jose; Rodriguez-Vega, Hector; Lloret-Sos, Carmen; Gil-Brusola, Ana; Luis Lopez-Hontangas, Jose; Nunez-Beltran, Maria; Tortosa-Carreres, Jordi; Angel Garcia-Garcia, Jose; Cordon, Lourdes; Puchades-Carrasco, Leonor; Carreras-Gil de Santivanes, Carmen; Pineda-Lucena, Antonio; Peman-Garcia, Javier 分享 收藏
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Lactobacillus supports Clostridiales to restrict gut colonization by multidrug-resistant Enterobacteriaceae 乳酸杆菌支持梭菌限制多药耐药肠杆菌科的肠道定植 Djukovic, Ana; Jose Garzon, Maria; Canlet, Cecile; Cabral, Vitor; Lalaoui, Rym; Garcia-Garcera, Marc; Rechenberger, Julia; Tremblay-Franco, Marie; Penaranda, Ivan; Puchades-Carrasco, Leonor; Pineda-Lucena, Antonio; Maria Gonzalez-Barbera, Eva; Salavert, Miguel; Luis Lopez-Hontangas, Jose; Sanz, Miguel A.; Sanz, Jaime; Kuster, Bernhard; Rolain, Jean-Marc; Debrauwer, Laurent; Xavier, Karina B.; Xavier, Joao B.; Ubeda, Carles 分享 收藏
Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort Conde, R.; Laires, R.; Goncalves, L. G.; Rizvi, A.; Barroso, C.; Villar, M.; Macedo, R.; Simoes, M. J.; Gaddam, S.; Lamosa, P.; Puchades-Carrasco, L.; Pineda-Lucena, A.; Patel, A. B.; Mande, S. C.; Banerjee, S.; Matzapetakis, M.; Coelho, A., V 分享 收藏
G9a inhibition by CM-272: Developing a novel anti-tumoral strategy for castration-resistant prostate cancer using 2D and 3D in vitro models CM-272抑制G9a: 使用2D和3D体外模型开发去势抵抗性前列腺癌的新型抗肿瘤策略 Moreira-Silva, Filipa; Outeiro-Pinho, Goncalo; Lobo, Joao; Guimaraes, Rita; Gaspar, Vitor M.; Mano, Joao F.; Agirre, Xabier; Pineda-Lucena, Antonio; Prosper, Felipe; Paramio, Jesus M.; Henrique, Rui; Correia, Margareta P.; Jeronimo, Carmen 分享 收藏
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming Colyn, Leticia; Alvarez-Sola, Gloria; Ujue Latasa, M.; Uriarte, Iker; Herranz, Jose M.; Arechederra, Maria; Vlachogiannis, George; Rae, Colin; Pineda-Lucena, Antonio; Casadei-Gardini, Andrea; Pedica, Federica; Aldrighetti, Luca; Lopez-Lopez, Angeles; Lopez-Gonzalvez, Angeles; Barbas, Coral; Ciordia, Sergio; Van Liempd, Sebastiaan M.; Falcon-Perez, Juan M.; Urman, Jesus; Sangro, Bruno; Vicent, Silve; Iraburu, Maria J.; Prosper, Felipe; Nelson, Leonard J.; Banales, Jesus M.; Luz Martinez-Chantar, Maria; Marin, Jose J. G.; Braconi, Chiara; Trautwein, Christian; Corrales, Fernando J.; Javier Cubero, F.; Berasain, Carmen; Fernandez-Barrena, Maite G.; Avila, Matias A. 分享 收藏
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