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B

Basil J. Greber

Lawrence Berkeley National Laboratory
H指数:28
被引数:3,750

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A genetic platform to deconvolve efficacy and toxicity reveals the on-target effects of CDK11 inhibition in vivo

一个用于解析功效和毒性的遗传平台揭示了CDK11抑制在体内的靶向效应

Nature Communications
IF15.7
2026-01-010
OA
Linda Julian; Lisa Crozier; Devon A. Lukow; Aditi Swamy; Sanat Mishra; Ryan A. Hagenson; Peter C. Sennhenn; Erin L. Sausville; Amy J. S. McGeoch; Sarah L. Thompson; Brianna E. Mendelson; Claudio E. Chuaqui; Lu Qiao; Anand Vasudevan; Kuan-Ting Lin; Sonam Bhatia; Thierry Bertomeu; Andrew Chatr‐aryamontri; Li Zhang; Matthew G. Rees; Melissa M. Ronan; Jennifer A. Roth; Timothy Nottoli; Suxia Bai; Jayalakshmi Lakshmipathi; Viswanathan Muthusamy; Jonathan G. Van Vranken; Gregory Gauthier-Coles; Steven P. Gygi; Joan C. Smith; Kendall L. Anderson; Sanjana Shah; Ranjit S. Bindra; Martin Akerman; David L. Spector; Basil J. Greber; Adrian R. Krainer; Jason M. Sheltzer
Sub-3 Å resolution protein structure determination by single-particle cryo-EM at 100 keV

单颗粒冷冻电镜在100 keV下实现亚3埃分辨率的蛋白质结构测定

Structure
IF4.3
2025-07-300
OAAI
Dimple Karia; Adrian F. Koh; Wen Yang; Victoria I. Cushing; Benjamin Basanta; Daniel B. Mihaylov; Sagar Khavnekar; Ondřej Vyroubal; Miloš Malínský; Ondřej Sháněl; Vojtěch Doležal; Jürgen Plitzko; Lingbo Yu; Gabriel C. Lander; A. Radu Aricescu; Basil J. Greber; Abhay Kotecha
Glacios 2 and Smart EPU accelerating Cryo-EM enabled structure-based drug design: A perfect combination to streamline single-particle data acquisition through advanced automation, ease of use, and higher throughput

Glacios 2和Smart EPU加速cryo-em启用基于结构的药物设计: 完美结合，通过先进的自动化，易用性和更高的吞吐量简化单粒子数据采集

JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2024-03-010
OAAI
Lengyel, Jeffrey; Koh, Adrian; Yu, Lingbo; Grollios, Fanis; van Knippenberg, Bart; Kotecha, Abhay; Greber, Basil; Pryor, Edward

研究方向

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E
Eva Nogales
H 指数:96论文数:414被引数:3.4万
A
Abhay Kotecha
H 指数:42论文数:198被引数:7,869
V
Victoria I. Cushing
H 指数:4论文数:11被引数:73
N
Nenad Ban
H 指数:77论文数:368被引数:2.4万
M
Markus Sutter
H 指数:34论文数:113被引数:4,369
C
Cheryl A. Kerfeld
H 指数:67论文数:298被引数:1.8万
A
Avinash B. Patel
H 指数:14论文数:27被引数:733
H
Henning Kirst
H 指数:20论文数:37被引数:1,609
J
Junjie Feng
H 指数:15论文数:68被引数:869
N
Nora Cronin
H 指数:21论文数:67被引数:1,952