Abhay Kotecha - Publications, H-index & Citations

Abhay Kotecha

thermo fischer scientific

42H指数

190论文数

7.9K被引数

收录论文 42

发表时间

Ligand-induced activation of RyR1 in native membranes 配体诱导的RyR1在原生膜中的激活

Nature Communications

IF15.7

2026-09-24

OAAI

Vasilii Mikirtumov; Sabrina Golusik; Ruifeng Huo; Thiemo Sprink; Nikita Balyschew; Wen Yang; Christoph Diebolder; Shuguang Yuan; Abhay Kotecha; Mikhail Kudryashev

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71 肠道病毒A71的保护性人源单克隆抗体的结构及功能分析

Science Advances

IF12.5

2026-06-05

OAAI

Daming Zhou; Abhay Kotecha; James T. Kelly; Peng-Nien Huang; Yi-Yin Chen; Thomas S. Walter; Helen M.E. Duyvesteyn; Raymond J. Owens; Shu-Yuan Ho; Tzou-Yien Lin; Elizabeth E. Fry; Jingshan Ren; Kuan-Ying A. Huang; David I. Stuart

Structural basis of signal peptide recognition by the signal peptidase complex 信号肽识别的信号肽酶复合物结构基础

Nature Communications

IF15.7

2026-05-22

OAAI

A. Manuel Liaci; Dimitrios Vismpas; Lisbeth R. Kjølbye; Ioannis Skalidis; Gilberto P. Pereira; Adrian Fujiet Koh; Mariska Gröllers-Mulderij; Abhay Kotecha; Paulo C. T. Souza; Friedrich Förster

Sub-3 Å resolution protein structure determination by single-particle cryo-EM at 100 keV 单颗粒冷冻电镜在100 keV下实现亚3埃分辨率的蛋白质结构测定

Structure

IF4.3

2025-07-30

OAAI

Dimple Karia; Adrian F. Koh; Wen Yang; Victoria I. Cushing; Benjamin Basanta; Daniel B. Mihaylov; Sagar Khavnekar; Ondřej Vyroubal; Miloš Malínský; Ondřej Sháněl; Vojtěch Doležal; Jürgen Plitzko; Lingbo Yu; Gabriel C. Lander; A. Radu Aricescu; Basil J. Greber; Abhay Kotecha

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants 不同SARS-CoV-2变体的病毒颗粒形态和病毒刺突蛋白结构

EMBO JOURNAL

IF8.3

2024-11-14

OAAI

Ke, Zunlong; Peacock, Thomas P.; Brown, Jonathan C.; Sheppard, Carol M.; Croll, Tristan, I; Kotecha, Abhay; Goldhill, Daniel H.; Barclay, Wendy S.; Briggs, John A. G.

CryoDRGN-ET: deep reconstructing generative networks for visualizing dynamic biomolecules inside cells Cryodrgn-et: 用于可视化细胞内动态生物分子的深度重建生成网络

NATURE METHODS

IF32.1

2024-07-18

PREAI

Rangan, Ramya; Feathers, Ryan; Khavnekar, Sagar; Lerer, Adam; Johnston, Jake D.; Kelley, Ron; Obr, Martin; Kotecha, Abhay; Zhong, Ellen D.

Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes

SCIENCE ADVANCES

IF12.5

2024-04-05

OAAI

Sauer, Paul V.; Cupellini, Lorenzo; Sutter, Markus; Bondanza, Mattia; Martin, Maria Agustina Dominguez; Kirst, Henning; Bina, David; Koh, Adrian Fujiet; Kotecha, Abhay; Greber, Basil J.; Nogales, Eva; Polivka, Tomas; Mennucci, Benedetta; Kerfeld, Cheryl A.

Glacios 2 and Smart EPU accelerating Cryo-EM enabled structure-based drug design: A perfect combination to streamline single-particle data acquisition through advanced automation, ease of use, and higher throughput Glacios 2和Smart EPU加速cryo-em启用基于结构的药物设计: 完美结合，通过先进的自动化，易用性和更高的吞吐量简化单粒子数据采集

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-01

OAAI

Lengyel, Jeffrey; Koh, Adrian; Yu, Lingbo; Grollios, Fanis; van Knippenberg, Bart; Kotecha, Abhay; Greber, Basil; Pryor, Edward

High-throughput Collaborative in situ Cryo-ET Enables the Molecular Atlas of C. reinhardtii

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-01

OAAI

Khavnekar, Sagar; Obr, Martin; Zhang, Xianjun; Kelley, Ron; Waltz, Florent; Engel, Ben; Plitzko, Juergen; Kotecha, Abhay

Cryo-EM structure of SRP68/72 reveals an extended dimerization domain with RNA-binding activity

NUCLEIC ACIDS RESEARCH

IF13.1

2024-02-16

OAAI

Zhong, Yichen; Feng, Junjie; Koh, Adrian F.; Kotecha, Abhay; Greber, Basil J.; Ataide, Sandro F.

New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy 来自青少年发作的突触核蛋白病的新的SNCA突变和 α-突触核蛋白丝的结构

ACTA NEUROPATHOLOGICA

IF9.3

2023-02-27

OAAI

Yang, Yang; Garringer, Holly J.; Shi, Yang; Lovestam, Sofia; Peak-Chew, Sew; Zhang, Xianjun; Kotecha, Abhay; Bacioglu, Mehtap; Koto, Atsuo; Takao, Masaki; Spillantini, Maria Grazia; Ghetti, Bernardino; Vidal, Ruben; Murzin, Alexey G.; Scheres, Sjors H. W.; Goedert, Michel

Structure of SARS-CoV-2 M protein in lipid nanodiscs

ELIFE

IF0

2022-10-20

OAAI

Dolan, Kimberly A.; Dutta, Mandira; Kern, David M.; Kotecha, Abhay; Voth, Gregory A.; Brohawn, Stephen G.

Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs 探索当代DEDs的高分辨率低温ET和断层图像平均功能

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2022-06-01

OAAI

Obr, Martin; Hagen, Wim J. H.; Dick, Robert A.; Yu, Lingbo; Kotecha, Abhay; Schur, Florian K. M.

Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy

ELIFE

IF0

2022-03-04

140

OAAI

Lovestam, Sofia; Koh, Fujiet Adrian; van Knippenberg, Bart; Kotecha, Abhay; Murzin, Alexey G.; Goedert, Michel; Scheres, Sjors H. W.

Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs (vol 28, pg 573, 2021)

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-07-20

OAAI

Kern, David M.; Sorum, Ben; Mali, Sonali S.; Hoel, Christopher M.; Sridharan, Savitha; Remis, Jonathan P.; Toso, Daniel B.; Kotecha, Abhay; Bautista, Diana M.; Brohawn, Stephen G.

Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-06-22

161

OAAI

Kern, David M.; Sorum, Ben; Mali, Sonali S.; Hoel, Christopher M.; Sridharan, Savitha; Remis, Jonathan P.; Toso, Daniel B.; Kotecha, Abhay; Bautista, Diana M.; Brohawn, Stephen G.

CryoET structures of immature HIV Gag reveal six-helix bundle

COMMUNICATIONS BIOLOGY

IF5.1

2021-04-16

OAAI

Mendonca, Luiza; Sun, Dapeng; Ning, Jiying; Liu, Jiwei; Kotecha, Abhay; Olek, Mateusz; Frosio, Thomas; Fu, Xiaofeng; Himes, Benjamin A.; Kleinpeter, Alex B.; Freed, Eric O.; Zhou, Jing; Aiken, Christopher; Zhang, Peijun

Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins

NATURE COMMUNICATIONS

IF15.7

2021-02-23

OAAI

Renner, Max; Dejnirattisai, Wanwisa; Carrique, Loic; Martin, Itziar Serna; Karia, Dimple; Ilca, Serban L.; Ho, Shu F.; Kotecha, Abhay; Keown, Jeremy R.; Mongkolsapaya, Juthathip; Screaton, Gavin R.; Grimes, Jonathan M.

Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71

NATURE COMMUNICATIONS

IF15.7

2020-10-16

OAAI

Huang, Kuan-Ying A.; Zhou, Daming; Fry, Elizabeth E.; Kotecha, Abhay; Huang, Peng-Nien; Yang, Shu-Li; Tsao, Kuo-Chien; Huang, Yhu-Chering; Lin, Tzou-Yien; Ren, Jingshan; Stuart, David I.

Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses

PLOS PATHOGENS

IF4.9

2020-09-29

OAAI

Chitray, Melanie; Kotecha, Abhay; Nsamba, Peninah; Ren, Jingshan; Maree, Sonja; Ramulongo, Tovhowani; Paul, Guntram; Theron, Jacques; Fry, Elizabeth E.; Stuart, David, I; Maree, Francois F.

研究方向