Jianhua Xu - Publications, H-index & Citations

Jianhua Xu

centre national de la recherche scientifique (cnrs)

26H指数

98论文数

2.3K被引数

收录论文 48

发表时间

Multivalency Effects: Example of Synthetic Ganglioside GM3 Analogues in the Study of Antitumor Agents

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-10-01

PREAI

Liu, Fang; Liu, Yan; Liu, Haipeng; Zhang, Jiaxu; Xu, Jianhua; Sollogoub, Matthieu; Zhang, Yongmin

CD9 downregulation activates EGFR/ERK/WAVE2 pathway to remodel F-actin and promote proliferation and migration of cholesteatoma epithelial cells CD9下调激活EGFR/ERK/WAVE2通路以重塑F-actin并促进胆脂瘤上皮细胞的增殖和迁移

International Immunopharmacology

IF4.7

2025-08-25

PREAI

Suling Zhuang; Miao Gao; Yonglan Liang; Xiaojing Guo; Qianfeng Li; Jianwei Lin; Jianhua Xu; Shengnan Ye

LncRNA ZNF295-AS1 modulates nasopharyngeal carcinoma progression via the miR-762/HDAC6 axis-mediated autophagy 长链非编码RNA ZNF295-AS1通过miR-762/HDAC6轴介导的自噬调控鼻咽癌进展

Cellular Signalling

IF3.7

2025-08-14

OAAI

Qiaozhi Jin; Ziyuan Chen; Si Ouyang; Jianhua Xu; Shengnan Ye

Targeting TRAP1-dependent metabolic reprogramming to overcome doxorubicin resistance in quiescent breast cancer 靶向TRAP1依赖性代谢重编程以克服静息状态乳腺癌的阿霉素耐药性

DRUG RESISTANCE UPDATES

IF21.7

2025-07-01

OAAI

Saleem, Muhammad Zubair; Huang, Ruyi; Huang, Yingying; Guo, Xin; Liu, Yang; Gao, Miao; Fan, Yinjuan; Chen, Zhe-Sheng; Ke, Zun-Fu; Ye, Shengnan; Xu, Jianhua

Curcumin derivative C210 induces Epstein-Barr virus lytic cycle and inhibits virion production by disrupting Hsp90 function

SCIENTIFIC REPORTS

IF3.9

2024-11-04

OAAI

Chen, Linli; Guo, Xiaojing; Lin, Wen; Huang, Yingying; Zhuang, Suling; Li, Qianfeng; Xu, Jianhua; Ye, Shengnan

Discovery of X10g as a selective PROTAC degrader of Hsp90a protein for treating breast cancer

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-11-01

PREAI

Jiang, Qingna; Fu, Minghai; Tang, Yuanling; Li, Ge; Tu, Guihui; Wu, Xinhua; Wu, Qiurong; Huang, Xiuwang; Xu, Jianhua; Liu, Yang; Wu, Lixian

The Hyperproliferation Mechanism of Cholesteatoma Based on Proteomics: SNCA Promotes Autophagy-Mediated Cell Proliferation Through the PI3K/AKT/CyclinD1 Signaling Pathway

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2023-09-01

OAAI

Gao, Miao; Xiao, Heng; Liang, Yonglan; Cai, Huimin; Guo, Xiaojing; Lin, Jianwei; Zhuang, Suling; Xu, Jianhua; Ye, Shengnan

Synthesis of Novel Dual Target Inhibitors of CDK12 and PARP1 and Their Antitumor Activities in HER2-Positive Breast Cancers

ACS OMEGA

IF4.3

2023-07-07

OAAI

Lin, Shanshan; Jiang, Qingna; Huang, Xiuwang; Xu, Jianhua; Wu, Lixian; Liu, Yang

Lucialdehyde B suppresses proliferation and induces mitochondria-dependent apoptosis in nasopharyngeal carcinoma CNE2 cells

PHARMACEUTICAL BIOLOGY

IF4.8

2023-06-15

OAAI

Liu, Lingxue; Yu, Zhangning; Chen, Jing; Liu, Benchen; Wu, Changhui; Li, Ye; Xu, Jianhua; Li, Peng

Redox-Responsive Lipidic Prodrug Nano-Delivery System Improves Antitumor Effect of Curcumin Derivative C210

PHARMACEUTICS

IF5.5

2023-05-19

OAAI

Guo, Xin; Wu, Min; Deng, Yanping; Liu, Yan; Liu, Yanpeng; Xu, Jianhua

Design, synthesis of novel triptolide-glucose conjugates targeting glucose Transporter-1 and their selective antitumor effect

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-08-01

OAAI

Liu, Yan; Huang, Jiaqing; Wu, Min; Liu, Bi; Lin, Qiaofa; Wu, Jingjing; Ouyang, Yuhua; Guo, Xin; Huang, Ruyi; Zhang, Yongmin; Xu, Jianhua

Ultrasensitive quantitation of circulating miR-195-5p with triple strand displacement amplification cascade

TALANTA

IF6.1

2022-05-01

PREAI

Wang, Xuzhi; Tang, Shuzhi; Ye, Shengnan; Cheng, Zhou; Xu, Jianhua; Li, Bo-wen; Chen, Zhuo

Synthesis of novel dual target inhibitors of PARP and EGFR and their antitumor activities in triple negative breast cancers 新型PARP和EGFR双靶点抑制剂的合成及其在三阴性乳腺癌中的抗肿瘤活性

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2022-05-01

PREAI

Lin, Shanshan; Zhang, Xiao; Yu, Zelei; Huang, Xiuwang; Xu, Jianhua; Liu, Yang; Wu, Lixian

Positive Feedback Regulation of Poly(ADP-ribose) Polymerase 1 and the DNA-PK Catalytic Subunit Affects the Sensitivity of Nasopharyngeal Carcinoma to Etoposide

ACS OMEGA

IF4.3

2022-01-07

OAAI

Zhang, Lingyu; Zhuang, Yingting; Tu, Guihui; Li, Ding; Fan, Yingjuan; Ye, Shengnan; Xu, Jianhua; Zheng, Ming; Wu, Ying; Wu, Lixian

Discovery of BP3 as an efficacious proteolysis targeting chimera (PROTAC) degrader of HSP90 for treating breast cancer 发现BP3作为HSP90的有效蛋白水解靶向嵌合体 (PROTAC) 降解剂用于治疗乳腺癌

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-01-01

PREAI

Liu, Quanyu; Tu, Guihui; Hu, Yan; Jiang, Qingna; Liu, Jingwen; Lin, Shanshan; Yu, Zelei; Li, Ge; Wu, Xinhua; Tang, Yuanling; Huang, Xiuwang; Xu, Jianhua; Liu, Yang; Wu, Lixian

Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086

DYES AND PIGMENTS

IF4.2

2021-05-01

PREAI

He, Chen; Zhang, Lei; Liu, Wenzhen; Huang, Yunmei; Hu, Ping; Dai, Tao; Xu, Jianhua; Chen, Zhuo

C0818, a novel curcumin derivative, induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function

ACTA PHARMACOLOGICA SINICA

IF8.4

2021-04-06

OAAI

Abdelmoaty, Ahmed Attia Ahmed; Zhang, Ping; Lin, Wen; Fan, Ying-juan; Ye, Sheng-nan; Xu, Jian-hua

Alpha-lipoic acid alleviates NAFLD and triglyceride accumulation in liver via modulating hepatic NLRP3 inflammasome activation pathway in type 2 diabetic rats

FOOD SCIENCE & NUTRITION

IF3.8

2021-03-13

OAAI

Ko, Chih-Yuan; Lo, Yangming Martin; Xu, Jian-Hua; Chang, Wen-Chang; Huang, Da-Wei; Wu, James Swi-Bea; Yang, Cho-Hua; Huang, Wen-Chung; Shen, Szu-Chuan

Aptamer-based CRISPR/Cas12a assay for the ultrasensitive detection of extracellular vesicle proteins 基于适配体的CRISPR/Cas12a检测细胞外囊泡蛋白的超灵敏检测

TALANTA

IF6.1

2021-01-01

OAAI

Li, Huilan; Xing, Shan; Xu, Jianhua; He, Yi; Lai, Yanzhen; Wang, Yu; Zhang, Ge; Guo, Songhe; Deng, Min; Zeng, Musheng; Liu, Wanli

Curcumin derivative C212 inhibits Hsp90 and eliminates both growing and quiescent leukemia cells in deep dormancy

CELL COMMUNICATION AND SIGNALING

IF8.9

2020-09-29

OAAI

Liu, Bi; Shen, Yunzhu; Huang, Huafang; Croce, Kimiko Della; Wu, Min; Fan, Yingjuan; Liu, Yang; Xu, Jianhua; Yao, Guang

研究方向