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杜

杜东书 (Dongshu Du)

shanghai university

H指数:24

被引数:2,468

个人简介

教授，博士（后）指导教师。主要研究方向：1. 高血压发病机制与神经信号网络调节（基础研究方向）；2. 智能精准神经降压康复系统（康复机器人）研发与产业化应用（人工智能与产业化方向）；3. 全脑电信号采集/储存/分析与大健康数据应用。

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

CircCdh7 induces astrogliosis and neuroinflammation to trigger hypertensive effects in the rostral ventrolateral medulla

CircCdh7诱导星形胶质细胞增生和神经炎症，以触发延髓头端腹外侧区的升压效应。

Cell & Bioscience

IF0

2025-10-210

OAAI

m6A reader YTHDF3 elicits hypertensive effects by degrading XRCC1 mRNA in the rostral ventrolateral medulla

m6A reader YTHDF3通过降解延髓头端腹外侧区的XRCC1 mRNA来引发升压效应

Free Radical Biology and Medicine

IF8.2

2025-06-070

PRE

Single-nucleus RNA sequencing reveals Cntnap2+ astrocytes triggering a hypertensive effect in the rostral ventrolateral medulla by disrupting glutamate uptake

单核RNA测序揭示Cntnap2+星形胶质细胞通过破坏谷氨酸摄取，在延髓头端腹外侧区触发升压效应。

Journal of Advanced Research

IF13

2025-06-020

OAAI

PDZD8 Dysregulation Mediates RVLM Neuronal Hyperexcitation Via Activation of Ca2+-Calpain-2 Signaling in Stress-Induced Hypertension

PDZD8失调通过激活Ca2+-Calpain-2信号通路介导应激性高血压中RVLM神经元的过度兴奋

MOLECULAR NEUROBIOLOGY

IF4.3

2025-05-260

PRE

Resveratrol reduces RVLM neuron activity via activating the AMPK/Sirt3 pathway in stress-induced hypertension

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-04-010

OAAI

Brain-Targeted Reactive Oxygen Species in Hypertension: Unveiling Subcellular Dynamics, Immune Cross-Talk, and Novel Therapeutic Pathways

脑靶向活性氧在高血压中的作用：揭示亚细胞动力学、免疫交叉对话及新型治疗途径

IF6.6

2025-03-280

OA

miR-193b-3p and miR-346 Exert Antihypertensive Effects in the Rostral Ventrolateral Medulla

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2024-07-020

OAAI

Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids

MOLECULAR PSYCHIATRY

IF10.1

2024-03-187

OA

CircRNA Galntl6 sponges miR-335 to ameliorate stress-induced hypertension through upregulating Lig3 in rostral ventrolateral medulla

IF11.9

2023-08-0112

OA

PDZD8-mediated endoplasmic reticulum-mitochondria associations regulate sympathetic drive and blood pressure through the intervention of neuronal mitochondrial homeostasis in stress-induced hypertension

NEUROBIOLOGY OF DISEASE

IF5.6

2023-07-017

OAAI

Microglia-derived TNF-α contributes to RVLM neuronal mitochondrial dysfunction via blocking the AMPK-Sirt3 pathway in stress-induced hypertension

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-06-016

OAAI

IFN-? deficiency in the rostral ventrolateral medulla contributes to stress-induced hypertension by impairing microglial synaptic engulfment

JOURNAL OF HYPERTENSION

IF4.1

2023-05-231

PRE

Ultrathin Niobium Carbide MXenzyme for Remedying Hypertension by Antioxidative and Neuroprotective Actions

超薄碳化铌mx酶通过抗氧化和神经保护作用治疗高血压

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-05-159

PRE

LncRNA INPP5F ameliorates stress-induced hypertension via the miR-335/Cttn axis in rostral ventrolateral medulla

CNS NEUROSCIENCE & THERAPEUTICS

IF5

2023-02-2711

OA

A Multifunctional Photoacoustic/Fluorescence Dual-Mode-Imaging Gold-Based Theranostic Nanoformulation without External Laser Limitations

ADVANCED MATERIALS

IF26.8

2022-04-0619

OA

PLIN2 Mediates Neuroinflammation and Oxidative/Nitrosative Stress via Downregulating Phosphatidylethanolamine in the Rostral Ventrolateral Medulla of Stressed Hypertensive Rats

inflammation research

IF4.1

2021-11-0115

OA

Deletion of Kv10.2 Causes Abnormal Dendritic Arborization and Epilepsy Susceptibility

Kv10.2基因缺失导致树突状异常和癫痫易感性

NEUROCHEMICAL RESEARCH

IF3.8

2020-10-082

PREAI

Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia

AGING AND DISEASE

IF6.9

2020-01-01903

OAAI

Leng, Zikuan; Zhu, Rongjia; Hou, Wei; Feng, Yingmei; Yang, Yanlei; Han, Qin; Shan, Guangliang; Meng, Fanyan; Du, Dongshu; Wang, Shihua; Fan, Junfen; Wang, Wenjing; Deng, Luchan; Shi, Hongbo; Li, Hongjun; Hu, Zhongjie; Zhang, Fengchun; Gao, Jinming; Liu, Hongjian; Li, Xiaoxia; Zhao, Yangyang; Yin, Kan; He, Xijing; Gao, Zhengchao; Wang, Yibin; Yang, Bo; Jin, Ronghua; Stambler, Ilia; Lim, Lee Wei; Su, Huanxing; Moskalev, Alexey; Cano, Antonio; Chakrabarti, Sasanka; Min, Kyung-Jin; Ellison-Hughes, Georgina; Caruso, Calogero; Jin, Kunlin; Zhao, Robert Chunhua

Increased Expression of Kv10.2 in the Hippocampus Attenuates Valproic Acid-Induced Autism-Like Behaviors in Rats

NEUROCHEMICAL RESEARCH

IF3.8

2019-11-1518

PREAI

Peptide-templated multifunctional nanoprobe for feasible electrochemical assay of intracellular kinase

BIOSENSORS & BIOELECTRONICS

IF10.5

2018-11-0118

PREAI

研究方向

高血压发病机制与神经信号网络调节（基础研究方向）智能精准神经降压康复系统康复机器人全脑电信号采集/储存/分析与大健康数据应用应激性高血压的机制研究胃黏膜损伤神经调控机制小胶质细胞应激性高血压应激性高血压电生理机制近五年代表性论文Wu QinMi YangCheng WenjingXia ChunmeiZhu Danian辅助性T细胞17Wang JFeng SNLi MLiu YMYan JYTang YFDu DS*钾离子通道30 (9):637-644.神经炎症褪黑素小胶质细胞极化高血压应激发展: 1013-1022.高血压苦味受体激活肠内分泌细胞447 (1-2):21-32.自噬流阻滞应激性高血压大鼠GABAB receptorgastric ischemia-reperfusion injury神经胶质瘤细胞迁移基质金属蛋白酶下丘脑室旁核小胶质细胞P2X7受体已授权专利编著教材或出版专著动物学

H 指数:23论文数:103被引数:1,501

H 指数:19论文数:97被引数:977

H 指数:16论文数:95被引数:1,652

H 指数:18论文数:79被引数:1,083

H 指数:26论文数:115被引数:1,841

H 指数:20论文数:140被引数:1,030

H 指数:6论文数:15被引数:146

H 指数:3论文数:24被引数:63

H 指数:9论文数:19被引数:333

H 指数:12论文数:56被引数:453