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Yechiel Shai

Weizmann Institute of Science

H指数:31

被引数:4,375

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Interaction of Pexiganan (MSI-78)-Derived Analogues Reduces Inflammation and TLR4-Mediated Cytokine Secretion: A Comparative Study

IF4.3

2023-05-129

OAAI

TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge

JOURNAL OF IMMUNOLOGY

IF3.4

2020-02-015

OAAI

The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice

IF4.9

2018-05-040

OAAI

Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-08-0135

OAAI

Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo

IF3

2016-09-198

PREAI

Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis

通过靶向TLR2二聚化中和促炎单核细胞可改善结肠炎

IF8.3

2016-02-1637

OAAI

Assembly of the TLR2/6 Transmembrane Domains Is Essential for Activation and Is a Target for Prevention of Sepsis

JOURNAL OF IMMUNOLOGY

IF3.4

2013-06-1536

OA

Trivalent Ultrashort Lipopeptides are Potent pH Dependent Antifungal Agents

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-02-0132

PREAI

Peptides Derived from the Transmembrane Domains of Toll-Like Receptors (TLR) 2/6 Interfere with Hetero-Associate with the TLRs and Inhibit their Activation

BIOPHYSICAL JOURNAL

IF3.1

2012-01-010

OAAI

Ultrashort Peptide Bioconjugates Are Exclusively Antifungal Agents and Synergize with Cyclodextrin and Amphotericin B

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2012-01-0144

OAAI

Oncolytic designer host defense peptide suppresses growth of human liposarcoma

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2010-11-2311

OAAI

Nanostructure Determines Antifungal Activity of De Novo Designed pH Dependent Histidine Containing Ultra-Short Lipopeptides

BIOPHYSICAL JOURNAL

IF3.1

2010-01-011

OAAI

Lipid Clustering by Three Homologous Arginine-Rich Antimicrobial Peptides is Insensitive to Amino Acid Arrangement

BIOPHYSICAL JOURNAL

IF3.1

2010-01-010

OAAI

Suppression of Human Solid Tumor Growth in Mice by Intratumor and Systemic Inoculation of Histidine-Rich and pH-Dependent Host Defense-like Lytic Peptides

CANCER RESEARCH

IF16.6

2009-04-15101

OA

Efficient clearance of Aspergillus fumigatus in murine lungs by an ultrashort antimicrobial lipopeptide, Palmitoyl-Lys-Ala-DAla-Lys

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2008-09-0141

OAAI

Specificity in transmembrane helix-helix interactions mediated by aromatic residues

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2007-07-01110

OAAI

Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides - Peptide properties and plausible modes of action

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-01-01367

PREAI

The identification of a minimal dimerization motif QXXS that enables homo- and hetero-association of transmembrane helices in vivo

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2005-07-0170

PREAI

A molecular mechanism for lipopolysaccharide protection of gram-negative bacteria from antimicrobial peptides

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2005-03-01262

OAAI

Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: Membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion

CANCER RESEARCH

IF16.6

2004-08-16141

PREAI