logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
M

Masato Yabuki

Takeda Pharmaceutical Company Ltd
H指数:12
被引数:579

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

一种新型LSD1抑制剂T-3775440破坏GFI1B-Containing复合物，导致AML细胞转分化和生长受损

MOLECULAR CANCER THERAPEUTICS
IF5.5
2017-02-0290
PREAI
Ishikawa, Yoshinori; Gamo, Kanae; Yabuki, Masato; Takagi, Shinji; Toyoshima, Kosei; Nakayama, Kazuhide; Nakayama, Akiko; Morimoto, Megumi; Miyashita, Hitoshi; Dairiki, Ryo; Hikichi, Yukiko; Tomita, Naoki; Tomita, Daisuke; Imamura, Shinichi; Iwatani, Misa; Kamada, Yusuke; Matsumoto, Satoru; Hara, Ryujiro; Nomura, Toshiyuki; Tsuchida, Ken; Nakamura, Kazuhide
Design, synthesis, and biological activities of novel hexahydropyrazino[1,2-a] indole derivatives as potent inhibitors of apoptosis (IAP) proteins antagonists with improved membrane permeability across MDR1 expressing cells
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2013-12-0123
PRE
Shiokawa, Zenyu; Hashimoto, Kentaro; Saito, Bunnai; Oguro, Yuya; Sumi, Hiroyuki; Yabuki, Masato; Yoshimatsu, Mie; Kosugi, Yohei; Debori, Yasuyuki; Morishita, Nao; Dougan, Douglas R.; Snell, Gyorgy P.; Yoshida, Sei; Ishikawa, Tomoyasu
Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2013-08-01106
PREAI
Okaniwa, Masanori; Hirose, Masaaki; Arita, Takeo; Yabuki, Masato; Nakamura, Akito; Takagi, Terufumi; Kawamoto, Tomohiro; Uchiyama, Noriko; Sumita, Akihiko; Tsutsumi, Shunichirou; Tottori, Tsuneaki; Inui, Yoshitaka; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu
Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2-a]pyrazine Scaffold as a Novel Proline Mimetic
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2013-01-2936
PREAI
Hashimoto, Kentaro; Saito, Bunnai; Miyamoto, Naoki; Oguro, Yuya; Tomita, Daisuke; Shiokawa, Zenyu; Asano, Moriteru; Kakei, Hiroyuki; Taya, Naohiro; Kawasaki, Masanori; Sumi, Hiroyuki; Yabuki, Masato; Iwai, Kenichi; Yoshida, Sei; Yoshimatsu, Mie; Aoyama, Kazunobu; Kosugi, Yohei; Kojima, Takashi; Morishita, Nao; Dougan, Douglas R.; Snell, Gyorgy P.; Imamura, Shinichi; Ishikawa, Tomoyasu
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2012-09-0119
PRE
Hirose, Masaaki; Okaniwa, Masanori; Miyazaki, Tohru; Imada, Takashi; Ohashi, Tomohiro; Tanaka, Yuta; Arita, Takeo; Yabuki, Masato; Kawamoto, Tomohiro; Tsutsumi, Shunichirou; Sumita, Akihiko; Takagi, Terufumi; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2012-08-019
PRE
Okaniwa, Masanori; Imada, Takashi; Ohashi, Tomohiro; Miyazaki, Tohru; Arita, Takeo; Yabuki, Masato; Sumita, Akihiko; Tsutsumi, Shunichirou; Higashikawa, Keiko; Takagi, Terufumi; Kawamoto, Tomohiro; Inui, Yoshitaka; Yoshida, Sei; Ishikawa, Tomoyasu
Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2012-03-1473
PREAI
Okaniwa, Masanori; Hirose, Masaaki; Imada, Takashi; Ohashi, Tomohiro; Hayashi, Youko; Miyazaki, Tohru; Arita, Takeo; Yabuki, Masato; Kakoi, Kazuyo; Kato, Juran; Takagi, Terufumi; Kawamoto, Tomohiro; Yao, Shuhei; Sumita, Akihiko; Tsutsumi, Shunichirou; Tottori, Tsuneaki; Oki, Hideyuki; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu

研究方向

暂未获取到该数据
S
Sei Yoshida
H 指数:12论文数:37被引数:593
T
Tomoyasu Ishikawa
H 指数:22论文数:122被引数:2,283
M
Masanori Okaniwa
H 指数:20论文数:65被引数:1,962
T
Takeo Arita
H 指数:9论文数:39被引数:738
T
Tomohiro Kawamoto
H 指数:28论文数:151被引数:2,735
T
Terufumi Takagi
H 指数:17论文数:61被引数:1,167
S
Shunichirou Tsutsumi
H 指数:8论文数:18被引数:484
A
Akihiko Sumita
H 指数:4论文数:11被引数:218
M
Masaaki Hirose
H 指数:33论文数:231被引数:5,477
J
Jason K. Yano
H 指数:25论文数:118被引数:4,922