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Douglas J. MacNeil

merck & company japan

46H指数
103论文数
1.0W被引数
收录论文 36
发表时间
Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice
err2023-03-27
err387
errOAAI
errQian, S; Chen, H; Weingarth, D; Trumbauer, ME; Novi, DE; Guan, XM; Yu, H; Shen, Z; Feng, Y; Frazier, E; Chen, AR; Camacho, RE; Shearman, LP; Gopal-Truter, S; MacNeil, DJ; Van der Ploeg, LHT; Marsh, DJ
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Expression profiling of the adhesion G protein-coupled receptor GPR133 (ADGRD1) in glioma subtypes
err2020-04-28
err10
errOAAI
errFrenster, Joshua D.; Kader, Michael; Kamen, Scott; Sun, James; Chiriboga, Luis; Serrano, Jonathan; Bready, Devin; Golub, Danielle; Ravn-Boess, Niklas; Stephan, Gabriele; Chi, Andrew S.; Kurz, Sylvia C.; Jain, Rajan; Park, Christopher Y.; Fenyo, David; Liebscher, Ines; Schoneberg, Torsten; Wiggin, Giselle; Newman, Robert; Barnes, Matt; Dickson, John K.; MacNeil, Douglas J.; Huang, Xinyan; Shohdy, Nadim; Snuderl, Matija; Zagzag, David; Placantonakis, Dimitris G.
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Discovery of Spirocyclic Aldosterone Synthase Inhibitors as Potential Treatments for Resistant Hypertension
err2016-12-06
err18
errOAAI
errPetrilli, Whitney L.; Hoyt, Scott B.; London, Clare; McMasters, Daniel; Verras, Andreas; Struthers, Mary; Cully, Doris; Wisniewski, Thomas; Ren, Ning; Bopp, Charlene; Sok, Andrea; Chen, Qing; Li, Ying; Tung, Elaine; Tang, Wei; Salituro, Gino; Knemeyer, Ian; Karanam, Bindhu; Clemas, Joseph; Zhou, Gaochao; Gibson, Jack; Shipley, Carrie Ann; MacNeil, Douglas J.; Duffy, Ruth; Tata, James R.; Ujjainwalla, Feroze; Ali, Amjad; Xiong, Yusheng
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GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growthGPR133 (ADGRD1) 是一种粘附性g蛋白偶联受体,是胶质母细胞瘤生长所必需的。
err2016-10-24
err58
errOAAI
errBayin, N. S.; Frenster, J. D.; Kane, J. R.; Rubenstein, J.; Modrek, A. S.; Baitalmal, R.; Dolgalev, I.; Rudzenski, K.; Scarabottolo, L.; Crespi, D.; Redaelli, L.; Snuderl, M.; Golfinos, J. G.; Doyle, W.; Pacione, D.; Parker, E. C.; Chi, A. S.; Heguy, A.; MacNeil, D. J.; Shohdy, N.; Zagzag, D.; Placantonakis, D. G.
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Effects of a novel Y5 antagonist in obese mice: Combination with food restriction or sibutramine
errOBESITY
IF4.7
err2012-09-06
err24
PREAI
errMashiko, Satoshi; Ishihara, Akane; Iwaasa, Hisashi; Moriya, Ryuichi; Kitazawa, Hidefumi; Mitobe, Yuko; Ito, Junko; Gomori, Akira; Matsushita, Hiroko; Takahashi, Toshiyuki; MacNeil, Douglas J.; Van der Ploeg, Lex H. T.; Fukami, Takehiro; Kanatani, Akio
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Liver and Adipose Expression Associated SNPs Are Enriched for Association to Type 2 Diabetes
err2010-05-06
err177
errOAAI
errZhong, Hua; Beaulaurier, John; Lum, Pek Yee; Molony, Cliona; Yang, Xia; MacNeil, Douglas J.; Weingarth, Drew T.; Zhang, Bin; Greenawalt, Danielle; Dobrin, Radu; Hao, Ke; Woo, Sangsoon; Fabre-Suver, Christine; Qian, Su; Tota, Michael R.; Keller, Mark P.; Kendziorski, Christina M.; Yandell, Brian S.; Castro, Victor; Attie, Alan D.; Kaplan, Lee M.; Schadt, Eric E.
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Pancreatic polypeptide enhances colonic muscle contraction and fecal output through neuropeptide Y Y4 receptor in mice
err2010-02-01
err22
PREAI
errMoriya, Ryuichi; Fujikawa, Toru; Ito, Junko; Shirakura, Takashi; Hirose, Hiroyasu; Suzuki, Jun; Fukuroda, Takahiro; MacNeil, Douglas J.; Kanatani, Akio
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Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice
err2009-12-01
err19
PREAI
errIto, Masahiko; Ishihara, Akane; Gomori, Akira; Egashira, Shinichiro; Matsushita, Hiroko; Mashiko, Satoshi; Ito, Junko; Ito, Makoto; Nakase, Kazuho; Haga, Yuji; Iwaasa, Hisashi; Suzuki, Takao; Ohtake, Norikazu; Moriya, Minoru; Sato, Nagaaki; MacNeil, Douglas J.; Takenaga, Norihiro; Tokita, Shigeru; Kanatani, Akio
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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
err2009-03-08
err255
errOAAI
errYang, Xia; Deignan, Joshua L.; Qi, Hongxiu; Zhu, Jun; Qian, Su; Zhong, Judy; Torosyan, Gevork; Majid, Sana; Falkard, Brie; Kleinhanz, Robert R.; Karlsson, Jenny; Castellani, Lawrence W.; Mumick, Sheena; Wang, Kai; Xie, Tao; Coon, Michael; Zhang, Chunsheng; Estrada-Smith, Daria; Farber, Charles R.; Wang, Susanna S.; Van Nas, Atila; Ghazalpour, Anatole; Zhang, Bin; MacNeil, Douglas J.; Lamb, John R.; Dipple, Katrina M.; Reitman, Marc L.; Mehrabian, Margarete; Lum, Pek Y.; Schadt, Eric E.; Lusis, Aldons J.; Drake, Thomas A.
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Blockade of MCH1 receptor signalling ameliorates obesity and related hepatic steatosis in ovariectomized mice
err2009-01-29
err28
errOAAI
errGomori, A.; Ishihara, A.; Ito, M.; Matsushita, H.; Ito, M.; Mashiko, S.; Iwaasa, H.; Matsuda, M.; Bednarek, M. A.; Qian, S.; MacNeil, D. J.; Kanatani, A.
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Silencing of Cytosolic or Mitochondrial Isoforms of Malic Enzyme Has No Effect on Glucose-stimulated Insulin Secretion from Rodent Islets
err2008-10-01
err70
errOAAI
errRonnebaum, Sarah M.; Jensen, Mette V.; Hohmeier, Hans E.; Burgess, Shawn C.; Zhou, Yun-Ping; Qian, Su; MacNeil, Douglas; Howard, Andrew; Thornberry, Nancy; Ilkayeva, Olga; Lu, Danhong; Sherry, A. Dean; Newgard, Christopher B.
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Antagonism of central melanin-concentrating hormone 1 receptor alleviates steatohepatitis in mice
err2008-06-03
err12
errOAAI
errIto, Makoto; Gomori, Akira; Suzuki, Jun; Tsujioka, Shigeharu; Sasaki, Minoru; Matsuda, Masao; Bednarek, Maria A.; Ito, Masahiko; Ishihara, Akane; Iwaasa, Hisashi; MacNeil, Douglas J.; Kanatani, Akio
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Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents
err2008-01-01
err12
PREAI
errShearman, Lauren P.; Stribling, D. Sloan; Camacho, Ramon E.; Rosko, Kimberly M.; Wang, Junying; Tong, Sharon; Feng, Yue; Marsh, Donald J.; Yu, Hong; Guan, Xiaoming; Spann, Stephanie K.; MacNeil, Douglas J.; Fong, Tung M.; Metzger, Joseph M.; Goulet, Mark T.; Hagmann, William K.; Plummer, Christopher W.; Finke, Paul E.; Mills, Sander G.; Shah, Shrenik K.; Truong, Quang; Van der Ploeg, L. H. T.; Maclntyre, D. Euan; Strack, Alison M.
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Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults
err2007-05-01
err128
errOAAI
errGantz, Ira; Erondu, Ngozi; Mallick, Madhuja; Musser, Bret; Krishna, Rajesh; Tanaka, Wesley K.; Snyder, Karen; Stevens, Cathy; Stroh, Mark A.; Zhu, Haiyuan; Wagner, John A.; MacNeil, Douglas J.; Heymsfield, Steven B.; Amatruda, John M.
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A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure
err2007-02-01
err42
PREAI
errMashiko, Satoshi; Ishihara, Akane; Iwaasa, Hisashi; Sano, Hideki; Ito, Junko; Gomori, Akira; Oda, Zenjun; Moriya, Ryuichi; Matsushita, Hiroko; Jitsuoka, Makoto; Okamoto, Osamu; MacNeil, Douglas J.; Van der Ploeg, Lex H. T.; Fukami, Takehiro; Kanatani, Akio
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Neuropeptide Y receptors as targets of obesity treatment
err2006-11-22
err9
PREAI
errIshihara, Akane; Moriya, Minoru; MacNeil, Douglas J.; Fukami, Takehiro; Kanatani, Akio
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Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults
err2006-10-01
err163
errOAAI
errErondu, Ngozi; Gantz, Ira; Musser, Bret; Suryawanshi, Shailaja; Mallick, Madhuja; Addy, Carol; Cote, Josee; Bray, George; Fujioka, Ken; Bays, Harold; Hollander, Priscilla; Sanabria-Bohorquez, Sandra M.; Eng, WaiSi; Langstrom, Bengt; Hargreaves, Richard J.; Burns, H. Donald; Kanatani, Akio; Fukami, Takehiro; MacNeil, Douglas J.; Gottesdiener, Keith M.; Amatruda, John M.; Kaufman, Keith D.; Heymsfield, Steven B.
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Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus
err2006-09-12
err99
errOAAI
errYoshimoto, Ryo; Miyamoto, Yasuhisa; Shimamura, Ken; Ishihara, Akane; Takahashi, Kazuhiko; Kotani, Hidehito; Chen, Airu S.; Chen, Howard Y.; MacNeil, Douglas J.; Kanatani, Akio; Tokita, Shigeru
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A neuropeptide YY5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice
err2006-05-02
err77
errOAAI
errIshihara, A; Kanatani, A; Mashiko, S; Tanaka, T; Hidaka, M; Gomori, A; Iwaasa, H; Murai, N; Egashira, S; Murai, T; Mitobe, Y; Matsushita, H; Okamoto, O; Sato, N; Jitsuoka, M; Fukuroda, T; Ohe, T; Guan, XM; MacNeil, DJ; Van der Ploegn, LHT; Nishikibe, M; Ishii, Y; Ihara, M; Fukami, T
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Detailed pharmacological characterization of GT-2331 for the rat histamine H3 receptor大鼠组胺H3受体GT-2331的详细药理学表征
err2006-01-01
err22
PREAI
errIto, S; Yoshimoto, R; Miyamoto, Y; Mitobe, Y; Nakamura, T; Ishihara, A; MacNeil, DJ; Kanatani, A; Tokita, S
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