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Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics Gupta, Yash; Savytskyi, Oleksandr, V; Coban, Matt; Venugopal, Amoghavarsha; Pleqi, Vasili; Weber, Caleb A.; Chitale, Rohit; Durvasula, Ravi; Hopkins, Christopher; Kempaiah, Prakasha; Caulfield, Thomas R. 分享 收藏
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel Gupta, Yash; Sharma, Neha; Singh, Snigdha; Romero, Jesus G.; Rajendran, Vinoth; Mogire, Reagan M.; Kashif, Mohammad; Beach, Jordan; Jeske, Walter; Poonam; Ogutu, Bernhards R.; Kanzok, Stefan M.; Akala, Hoseah M.; Legac, Jennifer; Rosenthal, Philip J.; Rademacher, David J.; Durvasula, Ravi; Singh, Agam P.; Rathi, Brijesh; Kempaiah, Prakasha 分享 收藏
Multi-Cellular Immunological Interactions Associated With COVID-19 Infections Verma, Jitender S.; Libertin, Claudia R.; Gupta, Yash; Khanna, Geetika; Kumar, Rohit; Arora, Balvinder S.; Krishna, Loveneesh; Fasina, Folorunso O.; Hittner, James B.; Antoniades, Athos; van Regenmortel, Marc H. V.; Durvasula, Ravi; Kempaiah, Prakasha; Rivas, Ariel L. 分享 收藏
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays Gupta, Yash; Maciorowski, Dawid; Zak, Samantha E.; Jones, Krysten A.; Kathayat, Rahul S.; Azizi, Saara-Anne; Mathur, Raman; Pearce, Catherine M.; Ilc, David J.; Husein, Hamza; Herbert, Andrew S.; Bharti, Ajay; Rathi, Brijesh; Durvasula, Ravi; Becker, Daniel P.; Dickinson, Bryan C.; Dye, John M.; Kempaiah, Prakasha 分享 收藏
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach 羟乙胺类似物的抗病毒评估: SARS-CoV-2主要蛋白酶 (3clpro) 的抑制剂,虚拟筛选和模拟方法 Gupta, Yash; Kumar, Sumit; Zak, Samantha E.; Jones, Krysten A.; Upadhyay, Charu; Sharma, Neha; Azizi, Saara-Anne; Kathayat, Rahul S.; Poonam; Herbert, Andrew S.; Durvasula, Ravi; Dickinson, Bryan C.; Dye, John M.; Rathi, Brijesh; Kempaiah, Prakasha 分享 收藏
Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy Gupta, Yash; Maciorowski, Dawid; Zak, Samantha E.; Kulkarni, Chandrashekhar, V; Herbert, Andrew S.; Durvasula, Ravi; Fareed, Jawed; Dye, John M.; Kempaiah, Prakasha 分享 收藏
High larvicidal efficacy of yeast-encapsulated orange oil against Aedes aegypti strains from Brazil Gomes, Bruno; Ogelio, Huarlen; Brant, Fabiane; Pereira-Pinto, Camila Jesus; Workman, Michael J.; Costa, Monique; Pereira Lima, Jose Bento; Martins, Ademir Jesus; Ramalho-Ortigao, Marcelo; Durvasula, Ravi; Hurwitz, Ivy; David, Mariana Rocha; Genta, Fernando Ariel 分享 收藏
The emerging paradigm of calcium homeostasis as a new therapeutic target for protozoan parasites Gupta, Yash; Goicoechea, Steven; Pearce, Catherine M.; Mathur, Raman; Romero, Jesus G.; Kwofie, Samuel K.; Weyenberg, Matthew C.; Daravath, Bharathi; Sharma, Neha; Poonam; Akala, Hoseah M.; Kanzok, Stefan M.; Durvasula, Ravi; Rathi, Brijesh; Kempaiah, Prakasha 分享 收藏
A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations Kumar, Sumit; Gupta, Yash; Zak, Samantha E.; Upadhyay, Charu; Sharma, Neha; Herbert, Andrew S.; Durvasula, Ravi; Potemkin, Vladimir; Dye, John M.; Poonam; Kempaiah, Prakasha; Rathi, Brijesh 分享 收藏
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Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure-Activity Relationship Studies Kumar, Sumit; Sharma, Prem Prakash; Shankar, Uma; Kumar, Dhruv; Joshi, Sanjeev K.; Pena, Lindomar; Durvasula, Ravi; Kumar, Amit; Kempaiah, Prakasha; Poonam; Rathi, Brijesh 分享 收藏
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Yeast-encapsulated essential oils: a new perspective as an environmentally friendly larvicide Workman, Michael J.; Gomes, Bruno; Weng, Ju-Lin; Ista, Linnea K.; Jesus, Camila P.; David, Mariana R.; Ramalho-Ortigao, Marcelo; Genta, Fernando A.; Matthews, Scott K.; Durvasula, Ravi; Hurwitz, Ivy 分享 收藏
Assessing the Dynamics and Complexity of Disease Pathogenicity Using 4-Dimensional Immunological Data Rivas, Ariel L.; Hoogesteijn, Almira L.; Antoniades, Athos; Tomazou, Marios; Buranda, Tione; Perkins, Douglas J.; Fair, Jeanne M.; Durvasula, Ravi; Fasina, Folorunso O.; Tegos, George P.; van Regenmortel, Marc H. V. 分享 收藏