未登录 Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial RO7300490的安全性及活性评估：一种靶向纤维细胞活化蛋白的双特异性CD40激动剂，用于晚期实体瘤患者的单臂、多中心、首次人体、Ⅰ期临床试验 Melero, Ignacio; Reis, Bernhard; Rusterholz, Corinne; Epp, Alexandra; Kratochwil, Nicole A.; Wu, Chun; Hettich, Michael; Kazantzidis, Georgios; Rieder, Natascha; Schwalie, Petra C.; Badillo, Solveig; Kumpesa, Nadine; Thommen, Andreas; Vugts, Danielle J.; Moreno, Victor; Lostes Bardaji, Julia; Alvarez, Eduardo Castanon; de Andrea, Carlos E.; Spanggaard, Iben; Lee, Dae Ho; Spicer, James; Thistlethwaite, Fiona; Oh, Do-Youn; Hollebecque, Antoine; Cirovic, Olivera; Symeonides, Stefan N. 分享 收藏
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Fibroblast activation protein (FAP)-CD40 (RO7300490) mediates intratumoral DC maturation and modulation of the tumor microenvironment Fibroblast activation protein (FAP)-CD40 (RO7300490) 介导肿瘤内树突状细胞成熟及肿瘤微环境的调控 Melero, I.; Reis, B.; Lostes Bardaji, M. J.; Spanggaard, I.; Lee, D. H.; Spicer, J.; Thistlethwaite, F.; Symeonides, S. N.; Oh, D-Y.; Hollebecque, A.; Rieder, N.; Schwalie, P.; Badillo, S.; Kumpesa, N.; Thommen, A.; Rusterholz, C.; Cirovic, O.; Kazantzidis, G.; Garcia, V. Moreno; Epp, A. 分享 收藏
Profiling the heterogeneity of colorectal cancer consensus molecular subtypes using spatial transcriptomics 使用空间转录组学分析结直肠癌共有分子亚型的异质性 Valdeolivas, Alberto; Amberg, Bettina; Giroud, Nicolas; Richardson, Marion; Galvez, Eric J. C.; Badillo, Solveig; Julien-Laferriere, Alice; Turos, Demeter; von Voithenberg, Lena Voith; Wells, Isabelle; Pesti, Benedek; Lo, Amy A.; Yangueez, Emilio; Das Thakur, Meghna; Bscheider, Michael; Sultan, Marc; Kumpesa, Nadine; Jacobsen, Bjorn; Bergauer, Tobias; Saez-Rodriguez, Julio; Rottenberg, Sven; Schwalie, Petra C.; Hahn, Kerstin 分享 收藏
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