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J

James D. Orth

University of Colorado System

H指数:22

被引数:3,994

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Spatial mechanisms of quality control during chaperone-mediated assembly of the proteasome

在分子伴侣介导的蛋白酶体组装过程中，质量控制的空间机制

NATURE COMMUNICATIONS

IF15.7

2025-04-090

OA

Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27217

OAAI

Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones

IF6.9

2022-06-017

OAAI

Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-04-0111

OAAI

Loss of p53 expression in cancer cells alters cell cycle response after inhibition o f exportin-1 but does not prevent cell death

IF3.4

2018-07-2312

OAAI

Rational combination of mTOR and Aurora kinase A inhibition in preclinical models of triple-negative breast cancer

MOLECULAR CANCER THERAPEUTICS

IF5.5

2018-01-010

PRE

Cell cycle specific effects and associated DNA damage of selective inhibitors of nuclear export (SINE)

CANCER RESEARCH

IF16.6

2016-07-150

PRE

Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor

SCIENTIFIC REPORTS

IF3.9

2015-09-2427

OAAI

Single cell longitudinal studies reveal cell cycle specific effects of selective inhibitors of nuclear export (SINE)

CANCER RESEARCH

IF16.6

2015-08-010

PRE

In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy

通过定量活体显微镜在异种移植肿瘤中的体内细胞周期分析

IF32.1

2015-04-1379

OAAI

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2014-11-0568

OAAI

Cell death when the SAC is out of commission

IF3.4

2014-10-287

OAAI

Using single cell fluorescent cell cycle reporters to study mechanisms of action of selective inhibitors of nuclear export (SINE).

MOLECULAR CANCER THERAPEUTICS

IF5.5

2013-11-010

PRE

Microtubule targeting antimitotic drugs induce a lower mitotic arrest than clinically less effective antimitotic Eg5 inhibitors in mouse xenografts.

MOLECULAR CANCER THERAPEUTICS

IF5.5

2013-11-010

PRE

Innate immunity in taxol-mediated tumor regression

CANCER RESEARCH

IF16.6

2012-04-010

PRE

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2012-02-15227

OAAI

Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells

IF10.1

2011-11-0115

OA

Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics

CANCER RESEARCH

IF16.6

2011-06-30141

OAAI

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

MOLECULAR CANCER THERAPEUTICS

IF5.5

2008-11-11122

OAAI

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5

CANCER RESEARCH

IF16.6

2008-05-01218

OAAI