Jo Ann Janovick - Publications, H-index & Citations

Jo Ann Janovick

Oregon Health & Science University

39H指数

105论文数

4.2K被引数

收录论文 41

发表时间

Rescue of mutant gonadotropin-releasing hormone receptor function independent of cognate receptor activity

SCIENTIFIC REPORTS

IF3.9

2020-06-29

OAAI

Smith, Emery; Janovick, Jo Ann; Bannister, Thomas D.; Shumate, Justin; Ganapathy, Vadivel; Scampavia, Louis; Spicer, Timothy P.

Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant

BIOCHEMICAL JOURNAL

IF4.3

2018-09-25

PREAI

Janovick, Jo Ann; Spicer, Timothy P.; Bannister, Thomas D.; Smith, Emery; Ganapathy, Vadivel; Scampavia, Louis

Receptor antagonism/agonism can be uncoupled from pharmacoperone activity

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2016-10-01

OAAI

Janovick, Jo Ann; Spicer, Timothy P.; Smith, Emery; Bannister, Thomas D.; Kenakin, Terry; Scampavia, Louis; Conn, P. Michael

Assay strategies for identification of therapeutic leads that target protein trafficking

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2015-08-01

OAAI

Conn, P. Michael; Spicer, Timothy P.; Scampavia, Louis; Janovick, Jo Ann

Transitioning pharmacoperones to therapeutic use: In vivo proof-of-principle and design of high throughput screens

PHARMACOLOGICAL RESEARCH

IF10.5

2014-05-01

OAAI

Conn, P. Michael; Smithson, David C.; Hodder, Peter S.; Stewart, M. David; Behringer, Richard R.; Smith, Emery; Ulloa-Aguirre, Alfredo; Janovick, Jo Ann

Pharmacoperone: What's in a word?

PHARMACOLOGICAL RESEARCH

IF10.5

2014-05-01

PREAI

Conn, P. Michael; Ulloa-Aguirre, Alfredo; Janovick, Jo Ann

Quality Control Autophagy Degrades Soluble ERAD-Resistant Conformers of the Misfolded Membrane Protein GnRHR

MOLECULAR CELL

IF16.6

2014-04-01

141

OAAI

Houck, Scott A.; Ren, Hong Yu; Madden, Victoria J.; Bonner, Jacob N.; Conlin, Michael P.; Janovick, Jo Ann; Conn, P. Michael; Cyr, Douglas M.

Restoration of testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-12-09

OAAI

Janovick, Jo Ann; Stewart, M. David; Jacob, Darla; Martin, L. D.; Deng, Jian Min; Stewart, C. Allison; Wang, Ying; Cornea, Anda; Chavali, Lakshmi; Lopez, Suhujey; Mitalipov, Shoukhrat; Kang, Eunju; Lee, Hyo-Sang; Manna, Pulak R.; Stocco, Douglas M.; Behringer, Richard R.; Conn, P. Michael

Species sequence differences determine the interaction of GnRH receptor with the cellular quality control system

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2013-12-01

OAAI

Cabrera-Wrooman, Alejandro; Janovick, Jo Ann; Conn, P. Michael

Salt Bridges Overlapping the Gonadotropin-Releasing Hormone Receptor Agonist Binding Site Reveal a Coincidence Detector for G Protein-Coupled Receptor Activation

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2011-08-01

OAAI

Janovick, Jo Ann; Pogozheva, Irina D.; Mosberg, Henry I.; Conn, P. Michael

Biochemical mechanism of pathogenesis of human gonadotropin-releasing hormone receptor mutants Thr104Ile and Tyr108Cys associated with familial hypogonadotropic hypogonadism

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2011-04-01

OAAI

Maya-Nunez, Guadalupe; Janovick, Jo Ann; Aguilar-Rojas, Arturo; Jardon-Valadez, Eduardo; Leanos-Miranda, Alfredo; Zarinan, Teresa; Ulloa-Aguirre, Alfredo; Michael Conn, P.

Salt bridge integrates GPCR activation with protein trafficking

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-02-16

OAAI

Janovick, Jo Ann; Conn, P. Michael

Drug development and the cellular quality control system

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2009-05-01

PREAI

Conn, P. Michael; Janovick, Jo Ann

Trafficking and quality control of the gonadotropin releasing hormone receptor in health and disease

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2009-02-01

OAAI

Conn, P. Michael; Janovick, Jo Ann

Increased plasma membrane expression of human follicle-stimulating hormone receptor by a small molecule thienopyr(im)idine

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2009-01-01

OAAI

Janovick, Jo Ann; Maya-Nunez, Guadalupe; Ulloa-Aguirre, Alfredo; Huhtaniemi, Ilpo T.; Dias, James A.; Verbost, Pieter; Conn, P. Michael

Refolding of misfolded mutant GPCR:: Post-translational pharmacoperone action in vitro

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2007-06-01

OAAI

Janovick, Jo Ann; Brothers, Shaun P.; Cornea, Anda; Bush, Eugene; Goulet, Mark T.; Ashton, Wallace T.; Sauer, Daryl R.; Haviv, Fortuna; Greer, Jonathan; Conn, P. Michael

Structure-activity relationship studies of gonadotropin-releasing hormone antagonists containing S-aryl/alkyl norcysteines and their oxidized derivatives

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-04-03

OAAI

Samant, Manoj P.; White, Richard; Hong, Doley J.; Croston, Glenn; Conn, P. Michael; Janovick, Jo Ann; Rivier, Jean

Specializations of a G-protein-coupled receptor that appear to aid with detection of frequency-modulated signals from its ligand

FASEB JOURNAL

IF4.2

2006-12-15

PREAI

Janovick, Jo Ann; Brothers, Shaun P.; Knollman, Paul E.; Conn, P. Michael