Jianhong Yang - Publications, H-index & Citations

Jianhong Yang

university of new south wales sydney

27H指数

105论文数

2.0K被引数

收录论文 49

发表时间

Folic acid alleviates neuroinflammation after intracerebral hemorrhage by epigenetically regulating the AMPD2/DCK/NF-κB pathway 叶酸通过表观遗传调控AMPD2/DCK/NF-κB通路减轻脑出血后的神经炎症

Phytomedicine

IF8.3

2026-08-01

PREAI

Xu, Yinbin; Hu, Jiahui; Wu, Menglu; Yang, Jianhong; Dai, Zifeng; Xu, Tianqi; Gao, Xiang; Huang, Yi; Zhou, Shengjun

Structure-based design and synthesis of 3-substituted-1,2,4-triazolo[1,5-a]pyrimidines as dual vinca/gatorbulin-site ligands for cancer treatment 基于结构的3-取代-1,2,4-三唑并[1,5-a]嘧啶的设计与合成，作为抗癌治疗的兼有长春碱/atrobulin位点的配体

European Journal of Medicinal Chemistry

IF5.9

2025-10-10

PREAI

Chufeng Zhang; Wei Yan; Hongxiu Chen; Maoru Sun; Fang Wang; Yilin Wang; Shuai Zhang; Li Liu; Qingqing Li; Xiuying Hu; Zhuang Yang; Jianhong Yang; Yong Li

Structure of quercetin 3,4′-dimethyl ether in complex with tubulin provides a rationale for drug design 槲皮素3,4'-二甲醚与微管蛋白复合物的结构为药物设计提供了合理的依据

Biochemical and Biophysical Research Communications

IF2.2

2025-06-23

PREAI

Yang Su; Wei Yan; Jianhong Yang; Falong Yang

CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury CMD-OPT模型能够发现一种强效且选择性的RIPK2抑制剂，作为治疗急性肝损伤的预临床试验候选药物。

Acta Pharmaceutica Sinica B

IF14.6

2025-05-13

OAAI

Yong Chen; Xue Yuan; Wei Yan; Yurong Zou; Haoche Wei; Yuhan Wei; Minghai Tang; Yulian Chen; Ziyan Ma; Tao Yang; Kongjun Liu; Baojian Xiong; Xiuying Hu; Jianhong Yang; Lijuan Chen

Case report: special imaging features in a uremic patient with intracranial infection caused by Ralstonia mannitolilytica, almost misdiagnosed as demyelinating disease

FRONTIERS IN MEDICINE

IF3

2025-01-14

OAAI

Kong, Hanxin; Ying, Hao; Yang, Jianhong

Research on the online prediction method of coarse aggregates packing void ratio based on particle shape and grading 基于颗粒形状和级配的粗集料堆积空隙率在线预测方法研究

CONSTRUCTION AND BUILDING MATERIALS

IF8

2025-01-01

PREAI

Cheng, Xiuyuan; Yang, Jianhong; Fang, Huaiying; Yu, Wenmin

Investigation on discrete fire spread behavior of latex foam under different bottom ventilation conditions

INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER

IF6.4

2024-12-01

PREAI

Lu, Dunhao; Huang, Dongmei; Ye, Rui; Yang, Jianhong; Wang, Wukang

Memantine alleviates cognitive impairment and hippocampal morphology injury in a mouse model of chronic alcohol exposure 美金刚减轻慢性酒精暴露小鼠模型的认知障碍和海马形态损伤

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2024-10-01

PREAI

Gao, Da-Peng; Weng, Qiu-Yan; Zhang, Yun-Yun; Ou, Yang-Xin; Niu, Yan-Fang; Lou, Qiong; Xie, Dong-Lin; Cai, Yu; Yang, Jian-Hong

Design, Synthesis, and Biological Evaluation of 5-Amino-4-fluoro-1H-benzo[d]imidazole-6-carboxamide Derivatives as Novel and Potential MEK/RAF Complex Inhibitors Based on the Clamp Strategy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-08-21

PREAI

Wang, Peng; Yuan, Yongting; Yang, Tao; Zou, Yurong; Tang, Minghai; Ma, Ziyan; Bo, Weichen; Qin, Songhui; Chen, Yong; Guo, Tao; Guo, Zhongning; Yang, Jianhong; Xiang, Mingli; Chen, Lijuan

Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2V617F-induced myeloproliferative neoplasms (Vol 12, 37, 2022)

BLOOD CANCER JOURNAL

IF11.6

2024-06-26

OAAI

Hu, Mengshi; Yang, Tao; Yang, Linyu; Niu, Lu; Zhu, Jinbing; Zhao, Ailin; Shi, Mingsong; Yuan, Xue; Tang, Minghai; Yang, Jianhong; Pei, Heying; Yang, Zhuang; Chen, Qiang; Ye, Haoyu; Niu, Ting; Chen, Lijuan

Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-03-01

PREAI

Zhang, Chufeng; Yan, Wei; Liu, Yan; Tang, Minghai; Teng, Yaxin; Wang, Fang; Hu, Xiuying; Zhao, Min; Yang, Jianhong; Li, Yong

NU6300 covalently reacts with cysteine-191 of gasdermin D to block its cleavage and palmitoylation

SCIENCE ADVANCES

IF12.5

2024-02-09

OAAI

Jiang, Xueqin; Zhang, Xinlu; Cai, Xiaoying; Li, Na; Zheng, Hongyu; Tang, Minghai; Zhu, Jiangli; Su, Kaiyue; Zhang, Ruijia; Ye, Neng; Peng, Jing; Zhao, Min; Wu, Wenshuang; Yang, Jianhong; Ye, Haoyu

Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-12-20

PREAI

Chen, Yong; Liu, Shuai; Wei, Yuhan; Wei, Haoche; Yuan, Xue; Xiong, Baojian; Tang, Minghai; Yang, Tao; Yang, Zhuang; Ye, Haoyu; Yang, Jianhong; Chen, Lijuan

Crystal structure of tubulin-barbigerone complex enables rational design of potent anticancer agents with isoflavone skeleton

PHYTOMEDICINE

IF8.3

2023-01-01

PREAI

Yan, Wei; Li, Yong; Liu, Yan; Wen, Yi; Pei, Heying; Yang, Jianhong; Chen, Lijuan

Identification of the target protein and molecular mechanism of honokiol in anti-inflammatory action

PHYTOMEDICINE

IF8.3

2023-01-01

PREAI

Cai, Xiaoying; Jiang, Xueqin; Zhao, Min; Su, Kaiyue; Tang, Minghai; Hong, Feng; Ye, Neng; Zhang, Ruijia; Li, Na; Wang, Lun; Xue, Linlin; Zhu, Zejiang; Chen, Lijuan; Yang, Jianhong; Wu, Wenshuang; Ye, Haoyu

?-Mangostin suppresses proliferation and invasion in osteosarcoma cells via inhibiting fatty acid synthase

JOURNAL OF FUNCTIONAL FOODS

IF4

2022-07-01

OAAI

Fan, Huijin; Guo, Yong; Zhang, Yaonan; Ding, Ning; Liu, Meiling; Ma, Xiaofeng; Yang, Jianhong

Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-06-28

PREAI

Yang, Jianhong; Li, Yong; Qiu, Qiang; Wang, Ruihan; Yan, Wei; Yu, Yamei; Niu, Lu; Pei, Heying; Wei, Haoche; Ouyang, Liang; Ye, Haoyu; Xu, Dingguo; Wei, Yuquan; Chen, Qiang; Chen, Lijuan

α-Linolenic Acid Suppresses Proliferation and Invasion in Osteosarcoma Cells via Inhibiting Fatty Acid Synthase

MOLECULES

IF4.6

2022-04-24

OAAI

Fan, Huijin; Huang, Wenyuan; Guo, Yong; Ma, Xiaofeng; Yang, Jianhong

Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2V617F-induced myeloproliferative neoplasms

BLOOD CANCER JOURNAL

IF11.6

2022-03-07

OAAI

Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-01-27

PREAI

Li, Yong; Liu, Yan; Zhu, Zejiang; Yan, Wei; Zhang, Chufeng; Yang, Zhuang; Bai, Peng; Tang, Minghai; Shi, Mingsong; He, Wen; Fu, Suhong; Liu, Jiang; Han, Kai; Li, Jiewen; Xie, Lixin; Ye, Haoyu; Yang, Jianhong; Chen, Lijuan

研究方向