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Ecteinascidin synthetic analogues: a new class of selective inhibitors of transcription, exerting immunogenic cell death in refractory malignant pleural mesothelioma Ecteinascidin合成类似物: 一类新的选择性转录抑制剂，在难治性恶性胸膜间皮瘤中引起免疫原性细胞死亡 Salaroglio, I. C.; Aviles, P.; Kopecka, J.; Merlini, A.; Napoli, F.; Righi, L.; Novello, S.; Sullivan, H.; Cuevas, C.; Scagliotti, G. V.; Riganti, C. 分享 收藏
S-p-bromobenzyl-glutathione cyclopentyl diester (BBGC) as novel therapeutic strategy to enhance trabectedin anti-tumor effect in soft tissue sarcoma preclinical models Pantano, F.; Simonetti, S.; Iuliani, M.; Guillen, M. J.; Cuevas, C.; Aviles, P.; Cavaliere, S.; Napolitano, A.; Cortellini, A.; Mazzocca, A.; Nibid, L.; Sabarese, G.; Perrone, G.; Gambarotti, M.; Righi, A.; Palmerini, E.; Stacchiotti, S.; Barisella, M.; Gronchi, A.; Valeri, S.; Sbaraglia, M.; Dei Tos, A. P.; Tonini, G.; Vincenzi, B. 分享 收藏
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ITCC-P4, a preclinical proof-of-concept drug testing platform as a tool for pharmacological screening in pediatric tumor models ITCC-P4，一个临床前概念验证药物测试平台，作为儿科肿瘤模型药理筛选的工具 Indersie, Emilie; Branchereau, Sophie; Fresneau, Brice; Chardot, Christophe; Surdez, Didier; Saint-Charles, Alexandra; da Costa, Maria Eugenia Marques; Carcaboso, Angel M.; Scotlandi, Katia; Moro, Massimo; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Chesler, Louis; Jones, Chris; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Guttke, Christina; Hattersley, Maureen; Colland, Frederic; Strougo, Ashley; Gurgen, Dennis; Hoffmann, Jens; Schueler, Julia; Aviles, Pablo M.; Guillen, Maria Jose; Federico, Aniello; Gopisetty, Apurva; Wierzbinska, Justyna Anna; Schlicker, Andreas; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Huebener, Nicole; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Stancato, Louis F.; Pfister, Stefan M.; Vassal, Gilles; Rief, Eva-Maria; Deas, Olivier 分享 收藏
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PM534 is a novel microtubule-destabilizing agent with high affinity and potent antineoplastic properties PM534是一种新型的微管去稳定剂，具有高亲和力和强大的抗肿瘤特性 Oliva, Maria Angela; Alvarez-Bernad, Beatriz; Lucena-Agell, Daniel; Diez, Marta Martinez; Guillen, Maria Jose; Nunez, Gema Santamaria; Munoz-Alonso, Maria Jose; Garrido-Martin, Eva M.; Aviles, Pablo; Cuevas, Carmen; Diaz, J. Fernando 分享 收藏
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Preclinical and randomized phase I studies of plitidepsin in adults with COVID-19 Varona, Jose F.; Landete, Pedro; Lopez-Martin, Jose A.; Estrada, Vicente; Paredes, Roger; Guisado-Vasco, Pablo; Fernandez de Orueta, Lucia; Torralba, Miguel; Fortun, Jesus; Vates, Roberto; Barberan, Jose; Clotet, Bonaventura; Ancochea, Julio; Carnevali, Daniel; Cabello, Noemi; Porras, Lourdes; Gijon, Paloma; Monereo, Alfonso; Abad, Daniel; Zuniga, Sonia; Sola, Isabel; Rodon, Jordi; Vergara-Alert, Julia; Izquierdo-Useros, Nuria; Fudio, Salvador; Jose Pontes, Maria; de Rivas, Beatriz; Giron de Velasco, Patricia; Nieto, Antonio; Gomez, Javier; Aviles, Pablo; Lubomirov, Rubin; Belgrano, Alvaro; Sopesen, Belen; White, Kris M.; Rosales, Romel; Yildiz, Soner; Reuschl, Ann-Kathrin; Thorne, Lucy G.; Jolly, Clare; Towers, Greg J.; Zuliani-Alvarez, Lorena; Bouhaddou, Mehdi; Obernier, Kirsten; McGovern, Briana L.; Rodriguez, M. Luis; Enjuanes, Luis; Fernandez-Sousa, Jose M.; Krogan, Nevan J.; Jimeno, Jose M.; Garcia-Sastre, Adolfo 分享 收藏
Plocabulin, a novel tubulin inhibitor, has antitumor activity in various patient-derived xenograft models of soft tissue sarcoma Wang, Yannick; Wozniak, Agnieszka; Cornillie, Jasmien; Lee, Che-Jui; Guillen, Maria Jose; Aviles, Pablo; Debiec-Rychter, Maria; Sciot, Raf; Schoffski, Patrick 分享 收藏
CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110 CD13作为抗体-药物缀合物的新肿瘤靶点: 缀合物MI130110的验证 Manuel Dominguez, Juan; Perez-Chacon, Gema; Jose Guillen, Maria; Jose Munoz-Alonso, Maria; Somovilla-Crespo, Beatriz; Cibrian, Danay; Acosta-Iborra, Barbara; Adrados, Magdalena; Munoz-Calleja, Cecilia; Cuevas, Carmen; Sanchez-Madrid, Francisco; Aviles, Pablo; Zapata, Juan M. 分享 收藏
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Plocabulin, a tubulin inhibitor, presents antitumor activity in patient-derived xenograft (PDX) models of gastrointestinal stromal tumor (GIST) Wozniak, Agnieszka; Wang, Yannick; Wellens, Jasmien; Gebreyohannes, Yemarshet K.; Jose Guillen, Maria; Galmarini, Carlos M.; Aviles, Pablo M.; Debiec-Rychter, Maria; Sciot, Raf; Schoffski, Patrick 分享 收藏
MI130004, a Novel Antibody-Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding In Vivo Activity against HER2-Expressing Tumors Aviles, Pablo; Manuel Dominguez, Juan; Jose Guillen, Maria; Jose Munoz-Alonso, Maria; Mateo, Cristina; Rodriguez-Acebes, Raquel; Manuel Molina-Guijarro, Jose; Francesch, Andres; Fernando Martinez-Leal, Juan; Munt, Simon; Galmarini, Carlos M.; Cuevas, Carmen 分享 收藏
Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells Galmarini, Carlos M.; Martin, Maud; Bouchet, Benjamin Pierre; Guillen-Navarro, Maria Jose; Martinez-Diez, Marta; Martinez-Leal, Juan Fernando; Akhmanova, Anna; Aviles, Pablo 分享 收藏
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