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M

Matan Thangavelu Thangavelu

agency for science technology & research (a*star)
H指数:6
被引数:416

个人简介

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荣誉奖项

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Modeling oxaliplatin resistance in colorectal cancer reveals a SERPINE1-based gene signature (RESIST-M) and therapeutic strategies for pro-metastatic CMS4 subtype

构建奥沙利铂耐药的结直肠癌模型揭示了基于SERPINE1的基因签名（RESIST-M）及促进转移的CMS4亚型的治疗策略

Cell Death & Disease
IF9.6
2025-07-160
OAAI
Stephen Qi Rong Wong; Mohua Das; Kenzom Tenzin; Niranjan Shirgaonkar; Huiwen Chua; Lin Xuan Chee; Ahpa Sae Yeoh; Astley Aruna Murugiah; Wei Yong Chua; Madelaine Skolastika Theardy; Ethan Jadon Subel; Matan Thangavelu Thangavelu; Jane Vin Chan; Choon Kong Yap; Iain Bee Huat Tan; Petros Tsantoulis; Sabine Tejpar; Jia Min Loo; Ramanuj DasGupta
CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancer

CAN-Scan：一个多组学表型驱动的精准肿瘤学平台，用于识别结直肠癌治疗反应的预后生物标志物

CELL REPORTS MEDICINE
IF10.6
2025-04-010
OAAI
Chia, Shumei; Seow, Justine Jia Wen; da Silva, Rafael Peres; Suphavilai, Chayaporn; Shirgaonkar, Niranjan; Murata-Hori, Maki; Zhang, Xiaoqian; Yong, Elena Yaqing; Pan, Jiajia; Thangavelu, Matan Thangavelu; Periyasamy, Giridharan; Yap, Aixin; Anand, Padmaja; Muliaditan, Daniel; Chan, Yun Shen; Wang, Siyu; Yong, Chua Wei; Hong, Nguyen; Ran, Gao; Sim, Ngak Leng; Guo, Yu Amanda; Teh, Andrea Xin Yi; Ling, Clarinda Chua Wei; Tan, Emile Kwong Wei; Cherylin, Fu Wan Pei; Chang, Meihuan; Han, Shuting; Seow-En, Isaac; Hui, Lionel Raphael Chen; Gan, Anna Hwee Hsia; Yap, Choon Kong; Ng, Huck Hui; Skanderup, Anders Jacobsen; Chinswangwatanakul, Vitoon; Riansuwan, Woramin; Trakarnsanga, Atthaphorn; Pithukpakorn, Manop; Tanjak, Pariyada; Chaiboonchoe, Amphun; Park, Daye; Kim, Dong Keon; Iyer, Narayanan Gopalakrishna; Tsantoulis, Petros; Tejpar, Sabine; Kim, Jung Eun; Kim, Tae Il; Sampattavanich, Somponnat; Tan, Iain Beehuat; Nagarajan, Niranjan; Dasgupta, Ramanuj
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma
FRONTIERS IN ONCOLOGY
IF3.3
2021-10-143
OAAI
Wong, Rachel L. Y.; Wong, Megan R. E.; Kuick, Chik Hong; Saffari, Seyed Ehsan; Wong, Meng Kang; Tan, Sheng Hui; Merchant, Khurshid; Chang, Kenneth T. E.; Thangavelu, Matan; Periyasamy, Giridharan; Chen, Zhi Xiong; Iyer, Prasad; Tan, Enrica E. K.; Soh, Shui Yen; Iyer, N. Gopalakrishna; Fan, Qiao; Loh, Amos H. P.
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC) (vol 64, 103220, 2021)
EBIOMEDICINE
IF10.8
2021-04-010
OAAI
Low, Joo-Leng; Lau, Dawn Pingxi; Zhang, Xiaoqian; Kwang, Xue-Lin; Rohatgi, Neha; Chan, Jane Vin; Chong, Fui-Teen; Wong, Stephen Qi Rong; Leong, Hui-Sun; Thangavelu, Matan Thangavelu; Rikka, Shivaji; Skanderup, Anders Martin Jacobsen; Tan, Daniel Shao Weng; Periyasamy, Giridharan; Koh, Judice Lie Yong; Iyer, N. Gopalakrishna; DasGupta, Ramanuj
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
EBIOMEDICINE
IF10.8
2021-02-0113
OAAI
Low, Joo-Leng; Lau, Dawn Pingxi; Zhang, Xiaoqian; Kwang, Xue-Lin; Rohatgi, Neha; Chan, Jane Vin; Chong, Fui-Teen; Wong, Stephen Qi Rong; Leong, Hui-Sun; Thangavelu, Matan Thangavelu; Rikka, Shivaji; Skanderup, Anders Martin Jacobsen; Tan, Daniel Shao Weng; Periyasamy, Giridharan; Koh, Judice Lie Yong; Iyer, N. Gopalakrishna; DasGupta, Ramanuj
A high-throughput chemical genetic screen reveals SALL4-induced metabolic vulnerabilities in cancer
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Tan, Justin L.; Li, Feng; Yeo, Joanna Z.; Yong, Kol Jia; Bassal, Mahmoud A.; Ng, Guo Hao; Lee, Y. Yin; Leong, Chung Yan; Tan, Hong Kee; Wu, Chan-Shuo; Liu, Bee Hui; Chan, Hon Man; Tan, Zi Hui; Chan, Yun Shen; Wang, Siyu; Lim, Zhi Han; Toh, Tan Boon; Hooi, Lissa; Low, Kia Ngee; Ma, Siming; Kong, Nikki R.; Stein, Alicia J.; Wu, Yue; Thangavelu, Matan T.; Suzuki, Atsushi; Periyasamy, Giridharan; Asara, John M.; Dan, Yock Young; Bonney, Glenn K.; Chow, Edward K.; Lu, Guo-Dong; Ng, Huck Hui; Kanagasundaram, Yoganathan; Ng, Siew; Tam, Wai Leong; Chai, Li; Tenen, Daniel G.
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation

通过诱导p53乙酰化靶向158位密码子p53-mutant癌症

NATURE COMMUNICATIONS
IF15.7
2020-04-2928
OAAI
Kong, Li Ren; Ong, Richard Weijie; TariD, Tuan Zea; Salleh, Nur Afiqah Binte Mohamed; Thangavelu, Matan; Chan, Jane Vin; Koh, Lie Yong Judice; Periyasamy, Giridharan; Lau, Jieying Amelia; Le, Thi Bich Uyen; Wang, Lingzhi; Lee, Miyoung; Kannan, Srinivasaraghavan; Verma, Chandra S.; Lim, Chwee Ming; Chng, Wee Joo; Lane, David P.; Venkitaraman, Ashok; Hung, Huynh The; Cheok, Chit Fang; Goh, Boon Cher
New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation
GASTROENTEROLOGY
IF25.1
2019-12-0145
OAAI
Tan, Justin L.; Li, Feng; Yeo, Joanna Z.; Yong, Kol Jia; Bassal, Mahmoud A.; Ng, Guo Hao; Lee, Y. Yin; Leong, Chung Yan; Tan, Hong Kee; Wu, Chan-Shuo; Liu, Hui; Chan, Tim H.; Tan, Zi Hui; Chan, Yun Shen; Wang, Siyu; Lim, Zhi Han; Toh, Tan Boon; Hooi, Lissa; Low, Kia Ngee; Ma, Siming; Kong, Nikki R.; Stein, Alicia J.; Wu, Yue; Thangavelu, Matan T.; Suzuki, Atsushi; Periyasamy, Giridharan; Asara, John M.; Dan, Yock Young; Bonney, Glenn K.; Chow, Edward K.; Lu, Guo-Dong; Ng, Huck Hui; Kanagasundaram, Yoganathan; Ng, Siew; Tam, Wai Leong; Tenen, Daniel G.; Chai, Li
Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy
NATURE COMMUNICATIONS
IF15.7
2018-11-22112
OAAI
Sharma, Ankur; Cao, Elaine Yiqun; Kumar, Vibhor; Zhang, Xiaoqian; Leong, Hui Sun; Wong, Angeline Mei Lin; Ramakrishnan, Neeraja; Hakimullah, Muhammad; Teo, Hui Min Vivian; Chong, Fui Teen; Chia, Shumei; Thangavelu, Matan Thangavelu; Kwang, Xue Lin; Gupta, Ruta; Clark, Jonathan R.; Periyasamy, Giridharan; Iyer, N. Gopalakrishna; DasGupta, Ramanuj
Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time
NATURE COMMUNICATIONS
IF15.7
2017-09-0570
OAAI
Chia, Shumei; Low, Joo-Leng; Zhang, Xiaoqian; Kwang, Xue-Lin; Chong, Fui-Teen; Sharma, Ankur; Bertrand, Denis; Toh, Shen Yon; Leong, Hui-Sun; Thangavelu, Matan T.; Hwang, Jacqueline S. G.; Lim, Kok-Hing; Skanthakumar, Thakshayeni; Tan, Hiang-Khoon; Su, Yan; Choo, Siang Hui; Hentze, Hannes; Tan, Iain B. H.; Lezhava, Alexander; Tan, Patrick; Tan, Daniel S. W.; Periyasamy, Giridharan; Koh, Judice L. Y.; Iyer, N. Gopalakrishna; DasGupta, Ramanuj

研究方向

暂未获取到该数据
G
Giridharan Periyasamy
H 指数:17论文数:66被引数:1,082
R
Ramanuj DasGupta
H 指数:42论文数:169被引数:9,748
N
N. Gopalakrishna Iyer
H 指数:44论文数:267被引数:9,412
H
Hui Sun Leong
H 指数:30论文数:108被引数:3,464
J
Joo-Leng Low
H 指数:9论文数:31被引数:433
X
Xiaoqian Zhang
H 指数:24论文数:64被引数:1,459
J
Jane Vin Chan
H 指数:9论文数:21被引数:319
S
Stephen Qi Rong Wong
H 指数:5论文数:9被引数:71
H
Huck‐Hui Ng
H 指数:76论文数:161被引数:3.7万
S
Shumei Chia
H 指数:8论文数:39被引数:875