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H

Hui Sun Leong

national cancer centre singapore (nccs)
H指数:30
被引数:3,443

个人简介

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教育背景

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工作经历

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荣誉奖项

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Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors

细胞外囊泡EGFR亚型D作为酪氨酸激酶抑制剂靶向鳞状细胞癌的联合药物的治疗应用

DEVELOPMENTAL CELL
IF8.7
2024-08-011
PRE
Toh, Shen Yon; Leong, Hui Sun; Chong, Fui Teen; Rodrigues-Junior, Dorival Mendes; Ren, Meng Jie; Kwang, Xue Lin; Lau, Dawn P. X.; Lee, Po-Hsien; Vettore, Andre Luiz; Teh, Bin Tean; Tan, Daniel S. W.; Iyer, N. Gopalakrishna
CRISPR screening in primary human lung fibroblasts and small airway epithelial cells identifies novel targets to reduce cellular senescence with potential to treat both COPD and IPF
EUROPEAN RESPIRATORY JOURNAL
IF21
2023-10-270
PRE
Mattsson, Johan; Bradley, Jenna; Sharma, Pooja; Escudero-Ibarz, Leire; Zhang, Bairu; Qian, Chen; O'Shea, Patrick; Wrench, Catherine; Karlsson, Maria; Overed-Sayer, Catherine; Rosa, Isabel; Pilling, James; Constantinou, Stephanie; Garriga, Lambert Montava; Quarantotti, Valentina; Leong, Hui Sun; Kim, Chang; Kentepozidou, Elissavet; Wiggins, Ceri; Paulin, Roxane; Rosenberg, Laura; Gianni, Davide; Olsson, Henric
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC) (vol 64, 103220, 2021)
EBIOMEDICINE
IF10.8
2021-04-010
OAAI
Low, Joo-Leng; Lau, Dawn Pingxi; Zhang, Xiaoqian; Kwang, Xue-Lin; Rohatgi, Neha; Chan, Jane Vin; Chong, Fui-Teen; Wong, Stephen Qi Rong; Leong, Hui-Sun; Thangavelu, Matan Thangavelu; Rikka, Shivaji; Skanderup, Anders Martin Jacobsen; Tan, Daniel Shao Weng; Periyasamy, Giridharan; Koh, Judice Lie Yong; Iyer, N. Gopalakrishna; DasGupta, Ramanuj
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
EBIOMEDICINE
IF10.8
2021-02-0113
OAAI
Low, Joo-Leng; Lau, Dawn Pingxi; Zhang, Xiaoqian; Kwang, Xue-Lin; Rohatgi, Neha; Chan, Jane Vin; Chong, Fui-Teen; Wong, Stephen Qi Rong; Leong, Hui-Sun; Thangavelu, Matan Thangavelu; Rikka, Shivaji; Skanderup, Anders Martin Jacobsen; Tan, Daniel Shao Weng; Periyasamy, Giridharan; Koh, Judice Lie Yong; Iyer, N. Gopalakrishna; DasGupta, Ramanuj
Pairing a prognostic target with potential therapeutic strategy for head and neck cancer
ORAL ONCOLOGY
IF3.9
2020-12-019
OAAI
Lek, Sze Min; Li, Ke; Tan, Qiu Xuan; Shannon, Nicholas B.; Ng, Wai Har; Hendrikson, Josephine; Tan, Joey W. S.; Lim, Hui Jun; Chen, Yudong; Koh, Kelvin K. N.; Skanthakumar, Thakshayeni; Kwang, Xue Lin; Chong, Fui Teen; Leong, Hui Sun; Tay, Gerald; Putri, Natascha Ekawati; Lim, Tony Kiat Hon; Hwang, Jacqueline S. G.; Ang, Mei Kim; Tan, Daniel S. W.; Tan, Ngian Chye; Tan, Hiang Khoon; Kon, Oi Lian; Soo, Khee Chee; Iyer, N. Gopalakrishna; Ong, Chin-Ann J.
Circulating extracellular vesicle-associated TGFβ3 modulates response to cytotoxic therapy in head and neck squamous cell carcinoma

循环细胞外小泡相关的TGFβ3调节头颈部鳞状细胞癌对细胞毒性治疗的反应

CARCINOGENESIS
IF2.9
2019-08-2220
PREAI
Rodrigues-Junior, Dorival Mendes; Tan, Soon Sim; Lim, Sai Kiang; Leong, Hui Sun; Melendez, Matias Eliseo; Niederauer Ramos, Cintia Regina; Viana, Luciano de Souza; Tan, Daniel S. W.; Carvalho, Andre Lopes; Iyer, N. Gopalakrishna; Vettore, Andre Luiz
Genomic Evaluation of Multiparametric Magnetic Resonance Imaging-visible and -nonvisible Lesions in Clinically Localised Prostate Cancer

临床定位前列腺癌的多参数磁共振成像可见和不可见病变的基因组评估

EUROPEAN UROLOGY ONCOLOGY
IF9.3
2019-02-0139
OAAI
Parry, Marina A.; Srivastava, Shambhavi; Ali, Adnan; Cannistraci, Alessio; Antonello, Jenny; Barros-Silva, Joao Diogo; Ubertini, Valentina; Ramani, Vijay; Lau, Maurice; Shanks, Jonathan; Nonaka, Daisuke; Oliveira, Pedro; Hambrock, Thomas; Leong, Hui Sun; Dhomen, Nathalie; Miller, Crispin; Brady, Ged; Dive, Caroline; Clarke, Noel W.; Marais, Richard; Baena, Esther
Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy
NATURE COMMUNICATIONS
IF15.7
2018-11-22112
OAAI
Sharma, Ankur; Cao, Elaine Yiqun; Kumar, Vibhor; Zhang, Xiaoqian; Leong, Hui Sun; Wong, Angeline Mei Lin; Ramakrishnan, Neeraja; Hakimullah, Muhammad; Teo, Hui Min Vivian; Chong, Fui Teen; Chia, Shumei; Thangavelu, Matan Thangavelu; Kwang, Xue Lin; Gupta, Ruta; Clark, Jonathan R.; Periyasamy, Giridharan; Iyer, N. Gopalakrishna; DasGupta, Ramanuj
GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers

在鳞状细胞癌中，gp13表达促进耐药性和肿瘤起始表型

ONCOGENE
IF7.3
2017-12-1940
OAAI
Rasheed, Suhail Ahmed Kabeer; Leong, Hui Sun; Lakshmanan, Manikandan; Raju, Anandhkumar; Dadlani, Dhivya; Chong, Fui-Teen; Shannon, Nicholas B.; Rajarethinam, Ravisankar; Skanthakumar, Thakshayeni; Tan, Ern Yu; Hwang, Jacqueline Siok Gek; Lim, Kok Hing; Tan, Daniel Shao-Weng; Ceppi, Paolo; Wang, Mei; Tergaonkar, Vinay; Casey, Patrick J.; Iyer, N. Gopalakrishna

研究方向

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N
N. Gopalakrishna Iyer
H 指数:44论文数:267被引数:9,366
C
Crispin Miller
H 指数:46论文数:202被引数:9,751
C
Caroline Dive
H 指数:98论文数:904被引数:4.6万
D
Daniel Shao-Weng Tan
H 指数:43论文数:297被引数:9,314
D
Dominic G. Rothwell
H 指数:43论文数:205被引数:1.0万
S
Sudhakar Sahoo
H 指数:14论文数:110被引数:1,132
G
Ged Brady
H 指数:30论文数:130被引数:6,885
F
Fui Teen Chong
H 指数:11论文数:43被引数:822
F
Fiona Blackhall
H 指数:89论文数:676被引数:4.0万
D
Dawn Pingxi Lau
H 指数:9论文数:23被引数:822