Marlene A. Jacobson - Publications, H-index & Citations

Marlene A. Jacobson

university of texas system

40H指数

97论文数

6.4K被引数

收录论文 40

发表时间

Synthesis, Biological Evaluation, and Computational Analysis of Biaryl Side-Chain Analogs of Solithromycin

CHEMMEDCHEM

IF3.4

2021-09-03

OAAI

Daher, Samer S.; Lee, Miseon; Jin, Xiao; Teijaro, Christiana N.; Wheeler, Steven E.; Jacobson, Marlene A.; Buttaro, Bettina; Andrade, Rodrigo B.

State-dependent inhibition of BK channels by the opioid agonist loperamide

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2021-08-06

OAAI

Vouga, Alexandre G.; Rockman, Michael E.; Yan, Jiusheng; Jacobson, Marlene A.; Rothberg, Brad S.

mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells

DISEASE MODELS & MECHANISMS

IF3.3

2019-10-16

OAAI

Brown, Robert A.; Voit, Antanina; Srikanth, Manasa P.; Thayer, Julia A.; Kingsbury, Tami J.; Jacobson, Marlene A.; Lipinski, Marta M.; Feldman, Ricardo A.; Awad, Ola

High-Throughput Ca2+ Flux Assay To Monitor Cyclic Nucleotide-Gated Channel Activity and Characterize Achromatopsia Mutant Channel Function 高通量Ca2通量测定以监测环核苷酸门控通道活性并表征色变片突变体通道功能

ACS CHEMICAL NEUROSCIENCE

IF3.9

2019-07-10

PREAI

Jacobson, Marlene A.; Jones, Laura J.; Colussi, Dennis J.; Tanaka, Jacqueline C.

Identification of Novel Inhibitors of DLK Palmitoylation and Signaling by High Content Screening

SCIENTIFIC REPORTS

IF3.9

2019-03-06

OAAI

Martin, Dale D. O.; Kanuparthi, Prasad S.; Holland, Sabrina M.; Sanders, Shaun S.; Jeong, Hey-Kyeong; Einarson, Margret B.; Jacobson, Marlene A.; Thomas, Gareth M.

Mechanism of BK Channel Inhibition by the Opioid Agonist Loperamide

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Vouga, Alexandre G.; Rockman, Michael E.; Jacobson, Marlene A.; Rothberg, Brad S.

Development of a High-Throughput Ca2+ Flux Screening Assay to Monitor Cyclic Nucleotide-Gated Channel Activity and Evaluate Achromatopsia Disease Mutant Channel Function

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Tanaka, Jacqueline; Almonte, Cristy; McDuffie, Elizabeth; Jones, Laura; Colussi, Dennis; Jacobson, Marlene

Targeting CDK9 reactivates epigenetically silenced genes in cancer

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Zhang, Hanghang; Pandey, Somnath; Travers, Meghan; Khowsathit, Jittasak; Morton, George; Sum, Hongxing; Barrero, Carlos A.; Merali, Carmen; Okamoto, Yasuyuki; Sato, Takahiro; Garriga, Judit; Bhanu, Natarajan V.; Simithy, Johayra; Patel, Bela; Madzo, Jozef; Raynal, Noel; Garcia, Benjamin A.; Jacobson, Marlene A.; Merali, Salim; Zhang, Yi; Childers, Wayne; Abou-Gharbia, Magid; Karanicolas, John; Baylin, Stephen B.; Zahnow, Cynthia A.; Jelinek, Jaroslav; Grana, Xavier; Issa, Jean-Pierre J.

Identifying novel potential epigenetic anti-cancer drugs from natural compounds using a phenotypic-based screening

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Zhang, Hanghang; Raynal, Noel J-M; Sato, Takahiro; Okamoto, Yasuyuki; Garriga, Judith; Garcia, Benjamin; Morton, George; Childers, Wayne; Jacobson, Marlene A.; Baylin, Stephen B.; Grana, Xavier; Abou-Gharbia, Magid; Issa, Jean-Pierre J.

Patient derived phenotypic high throughput assay to discover treatments for Tay-Sachs disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2017-01-01

PREAI

Jacobson, Marlene A.; Colussi, Dennis J.

A phenotypic cell-based screen to identify novel potential epigenetic anti-cancer drugs from natural compounds

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Zhang, Hanghang; Raynal, Noel J. -M; Sato, Takahiro; Okamoto, Yasuyuki; Garriga, Judit; Morton, George; Childers, Wayne; Jacobson, Marlene A.; Baylin, Stephen B.; Grana, Xavier; Abou-Gharbia, Magid; Issa, Jean-Pierre J.

Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-02-26

OAAI

Glassford, Ian; Teijaro, Christiana N.; Daher, Samer S.; Weil, Amy; Small, Meagan C.; Redhu, Shiv K.; Colussi, Dennis J.; Jacobson, Marlene A.; Childers, Wayne E.; Buttaro, Bettina; Nicholson, Allen W.; MacKerell, Alexander D., Jr.; Cooperman, Barry S.; Andrade, Rodrigo B.

Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2016-01-13

OAAI

Pero, Joseph E.; Rossi, Michael A.; Kelly, Michael J., III; Lehman, Hannah D. G. F.; Layton, Mark E.; Garbaccio, Robert M.; O'Brien, Julie A.; Magliaro, Brian C.; Uslaner, Jason M.; Huszar, Sarah L.; Fillgrove, Kerry L.; Tang, Cuyue; Kuo, Yuhsin; Joyce, Leo A.; Sherer, Edward C.; Jacobson, Marlene A.

A phenotypic screen to discover novel epigenetic anticancer drugs from natural compounds

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Zhang, Hanghang; Raynal, Noel; Sato, Takahiro; Okamoto, Yasuyuki; Henry, Ryan; Andrews, Andrew J.; Morton, George; Childers, Wayne; Jacobson, Marlene A.; Abou-Gharbia, Magid; Issa, Jean-Pierre J.

Discovering potential epigenetic anti-cancer drugs derived from natural compounds

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Zhang, Hanghang; Raynal, Noel J-M; Jacobson, Marlene A.; Issa, Jean-Pierre

The M1 Muscarinic Receptor Allosteric Agonists AC-42 and 1-[1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one Bind to a Unique Site Distinct from the Acetylcholine Orthosteric Site

MOLECULAR PHARMACOLOGY

IF3

2010-10-01

PREAI

Jacobson, Marlene A.; Kreatsoulas, Constantine; Pascarella, Danette M.; O'Brien, Julie A.; Sur, Cyrille

Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2010-07-12

OAAI

Garbaccio, Robert M.; Brnardic, Edward J.; Fraley, Mark E.; Hartman, George D.; Hutson, Pete H.; O'Brien, Julie A.; Magliaro, Brian C.; Uslaner, Jason M.; Huszar, Sarah L.; Fillgrove, Kerry L.; Small, James H.; Tang, Cuyue; Kuo, Yuhsin; Jacobson, Marlene A.

Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-09-15

263

OAAI

Ma, Lei; Seager, Matthew; Wittmann, Marion; Jacobson, Marlene; Bickel, Denise; Burno, Maryann; Jones, Keith; Graufelds, Valerie Kuzmick; Xu, Guangping; Pearson, Michelle; McCampbell, Alexander; Gaspar, Renee; Shughrue, Paul; Danziger, Andrew; Regan, Christopher; Flick, Rose; Pascarella, Danette; Garson, Susan; Doran, Scott; Kreatsoulas, Constantine; Veng, Lone; Lindsley, Craig W.; Shipe, William; Kuduk, Scott; Sur, Cyrille; Kinney, Gene; Seabrook, Guy R.; Ray, William J.

The Behavioral and Neurochemical Effects of a Novel D-Amino Acid Oxidase Inhibitor Compound 8 [4H-Thieno [3,2-b]pyrrole-5-carboxylic Acid] and D-Serine

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2009-03-01

PREAI

Smith, Sean M.; Uslaner, Jason M.; Yao, Lihang; Mullins, Chadwick M.; Surles, Nathan O.; Huszar, Sarah L.; McNaughton, Caitlyn H.; Pascarella, Danette M.; Kandebo, Monika; Hinchliffe, Richard M.; Sparey, Tim; Brandon, Nicholas J.; Jones, Brian; Venkatraman, Shankar; Young, Mary Beth; Sachs, Nancy; Jacobson, Marlene A.; Hutson, Peter H.

Cardioprotection by ecto-5′-nucleotidase (CD73) and A2B adenosine receptors

CIRCULATION

IF38.6

2007-03-27

427

PREAI

Eckle, Tobias; Krahn, Thomas; Grenz, Almut; Koehler, David; Mittelbronn, Michel; Ledent, Catherine; Jacobson, Marlene A.; Osswald, Hartmut; Thompson, Linda F.; Unertl, Klaus; Eltzschig, Holger K.

研究方向