未登录 分享 收藏
In vitro and in vivo characterization of novel MAT2A allosteric inhibitors Pei, Zhonghua; Alam, Muzaffar; Bhola, Neil; Cleary, Leah; Drummond, Jake; Fisher, Marcus; Fleury, Melissa; Garcia, Candy; Givmanesh, Atieh; Xin Linghu; McSpadden, Ethan; Mounir, Zineb; Neilan, Claire; Newby, Zach; Perumal, Senthil; Steel, Richard; Sutton, James; Vaidya, Kedar; Wagle, Marie-Claire; Wang, Jianhong; Yao, Bing; Lackner, Mark; Dillon, Michael P. 分享 收藏
Mat2A Inhibitors decrease growth, increase senescence and p53 stability in MTAP-deleted cancer cells Bhola, Neil; Givmanesh, Atieh; Wagle, Marie-Claire; Garcia, Candy; Vaidya, Kedar; Cleary, Leah; Pei, Zhonghua; Lackner, Mark; Mounir, Zineb 分享 收藏
CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms Castillo, Joseph; Wu, Esther; Lowe, Christopher; Srinivasan, Shrividhya; McCord, Ron; Wagle, Marie-Claire; Jayakar, Sangeeta; Edick, Melissa Gonzalez; Eastham-Anderson, Jeffrey; Liu, Bonnie; Hutchinson, Katherine E.; Jones, Wendell; Stokes, Matthew P.; Tarighat, Somayeh S.; Holcomb, Thomas; Glibicky, Andrew; Romero, F. Anthony; Magnuson, Steven; Huang, Shih-Min A.; Plaks, Vicki; Giltnane, Jennifer M.; Lackner, Mark R.; Mounir, Zineb 分享 收藏
Association of tumor fusion burden with immune presence and androgen sensitivity in prostate cancer Wagle, Marie; Yuen, Kobe; Kadel, Edward E.; Holcomb, Thomas; Srinivasan, Shrividhya; Castillo, Joseph; Halligan, Dan; Carr, Adrian; Bylesjo, Max; Augley, Julian; Daminelli, Simone; Kockx, Mark; Waumans, Yannick; Giltnane, Jennifer; Mounir, Zineb 分享 收藏
Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology Okrah, K.; Tarighat, S.; Liu, B.; Koeppen, H.; Wagle, M. C.; Cheng, G.; Sun, C.; Dey, A.; Chang, M. T.; Sumiyoshi, T.; Mounir, Z.; Cummings, C.; Hampton, G.; Amler, L.; Fridlyand, J.; Hegde, P. S.; Turley, S. J.; Lackner, M. R.; Huang, S. M. 分享 收藏
A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types Wagle, Marie-Claire; Kirouac, Daniel; Klijn, Christiaan; Liu, Bonnie; Mahajan, Shilpi; Junttila, Melissa; Moffat, John; Merchant, Mark; Huw, Ling; Wongchenko, Matthew; Okrah, Kwame; Srinivasan, Shrividhya; Mounir, Zineb; Sumiyoshi, Teiko; Haverty, Peter M.; Yauch, Robert L.; Yan, Yibing; Kabbarah, Omar; Hampton, Garret; Amler, Lukas; Ramanujan, Saroja; Lackner, Mark R.; Huang, Shih-Min A. 分享 收藏
Analysis of non-metastatic HCC patient tumors revealed the significance of cell cycle regulation and tumor immunity in association with overall survival and identified clinically relevant druggable targets Miao, Pei-Zhen; Cheng, Jeff; Okrah, Kwame; Liu, Bonnie; Sun, Charlie; Cao, Grace; Guo, Tony; Fu, Shijing; Wagle, Marie-Claire; Blackwood, Elizabeth; Shames, David; Hampton, Garret; Amler, Lukas; Kiermaier, Astrid; Fridlyand, Yevgeniya; Lackner, Mark; Huang, Shih-Min; Zhou, Jian; Dai, Zhi 分享 收藏
A role for FOXO1 in BCR-ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia Wagle, M.; Eiring, A. M.; Wongchenko, M.; Lu, S.; Guan, Y.; Wang, Y.; Lackner, M.; Amler, L.; Hampton, G.; Deininger, M. W.; O'Hare, T.; Yan, Y. 分享 收藏
Combination of the ERK inhibitor GDC-0994 with the MEK inhibitor cobimetinib significantly enhances anti-tumor activity in KRAS and BRAF mutant tumor models Merchant, M.; Chan, J.; Orr, C.; Cheng, J.; Wang, X.; Hunsaker, T.; Wagle, M. C.; Huang, S. A.; Tremayne, J.; Ngu, H.; Solon, M.; Eastham-Anderson, J.; Koeppen, H.; Friedman, L.; Belvin, M.; Moffat, J.; Junttila, M. 分享 收藏
Expanded biomarker results from a phase I dose escalation study of GDC-0032, a beta isoform-sparing PI3K inhibitor Wilson, Timothy R.; Savage, Heidi; O'Brien, Carol; Sanabria, Sandra; Lin, Ray S.; Wagle, Marie-Claire; Yan, Yibing; Lackner, Mark R.; Parmar, Hema; Hsu, Jerry Y.; Juric, Dejan; Krop, Ian E.; Ramanathan, Ramesh K.; Von Hoff, Daniel D.; Baselga, Jose 分享 收藏
Sensitivity of endometrial cancer cells to inhibitors targeting different nodes of the PI3K pathway and their combination with a MEK inhibitor Wongchenko, Matthew J.; Guan, Yinghui; Wagle, Marie-Claire; Ryner, Lisa; Lu, Shan; Koeppen, Hartmut; Hampton, Garret; Lackner, Mark; Wang, Yulei; Yan, Yibing 分享 收藏
分享 收藏
分享 收藏
R-Spondin family members regulate the Wnt pathway by a common mechanism Kim, Kyung-Ah; Wagle, Marie; Tran, Karolyn; Zhan, Xiaoming; Dixon, Melissa A.; Liu, Shouchun; Gros, Delphine; Korver, Wouter; Yonkovich, Shirlee; Tomasevic, Nenad; Binnerts, Minke; Abo, Arie 分享 收藏
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 Binnerts, Minke E.; Kim, Kyung-Ah; Bright, Jessica M.; Patel, Sejal M.; Tran, Karolyn; Zhou, Mei; Leung, John M.; Liu, Yi; Lomas, Woodrow E., III; Dixon, Melissa; Hazell, Sophie A.; Wagle, Marie; Nie, Wen-Sheng; Tomasevic, Nenad; Williams, Jason; Zhan, Xiaoming; Levy, Michael D.; Funk, Walter D.; Abo, Arie 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
