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Systematic perturbation screens identify regulators of inflammatory macrophage states and a role for TNF mRNA m6A modification Haag, Simone M.; Xie, Shiqi; Eidenschenk, Celine; Fortin, Jean-Philippe; Callow, Marinella; Costa, Mike; Lun, Aaron; Cox, Chris; Wu, Sunny Z.; Pradhan, Rachana N.; Lock, Jaclyn; Kuhn, Julia A.; Holokai, Loryn; Thai, Minh; Freund, Emily; Nissenbaum, Ariane; Keir, Mary; Bohlen, Christopher J.; Martin, Scott; Geiger-Schuller, Kathryn; Hejase, Hussein A.; Yaspan, Brian L.; Carlos, Sandra Melo; Turley, Shannon J.; Murthy, Aditya 分享 收藏
Durable lymph-node expansion is associated with the efficacy of therapeutic vaccination Najibi, Alexander J.; Lane, Ryan S.; Sobral, Miguel C.; Bovone, Giovanni; Kang, Shawn; Freedman, Benjamin R.; Estupinan, Joel Gutierrez; Elosegui-Artola, Alberto; Tringides, Christina M.; Dellacherie, Maxence O.; Williams, Katherine; Ijaz, Hamza; Muller, Soren; Turley, Shannon J.; Mooney, David J. 分享 收藏
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Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors 联合PD-L1/tgf β 阻断可在免疫排除的肿瘤中扩增和分化干细胞样CD8 T细胞 Castiglioni, Alessandra; Yang, Yagai; Williams, Katherine; Gogineni, Alvin; Lane, Ryan S.; Wang, Amber W.; Shyer, Justin A.; Zhang, Zhe; Mittman, Stephanie; Gutierrez, Alan; Astarita, Jillian L.; Thai, Minh; Hung, Jeffrey; Yang, Yeqing Angela; Pourmohamad, Tony; Himmels, Patricia; De Simone, Marco; Elstrott, Justin; Capietto, Aude-Helene; Cubas, Rafael; Modrusan, Zora; Sandoval, Wendy; Ziai, James; Gould, Stephen E.; Fu, Wenxian; Wang, Yulei; Koerber, James T.; Sanjabi, Shomyseh; Mellman, Ira; Turley, Shannon J.; Mueller, Soeren 分享 收藏
CD8+T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy CD8 T细胞内源性IL-6信号促进对anti-PD-L1免疫疗法的抵抗 Huseni, Mahrukh A.; Wang, Lifen; Klementowicz, Joanna E.; Yuen, Kobe; Breart, Beatrice; Orr, Christine; Liu, Li-fen; Li, Yijin; Gupta, Vinita; Li, Congfen; Rishipathak, Deepali; Peng, Jing; Senbabaoglu, Yasin; Modrusan, Zora; Keerthivasan, Shilpa; Madireddi, Shravan; Chen, Ying-Jiun; Fraser, Eleanor J.; Leng, Ning; Hamidi, Habib; Koeppen, Hartmut; Ziai, James; Hashimoto, Kenji; Fasso, Marcella; Williams, Patrick; McDermott, David F.; Rosenberg, Jonathan E.; Powles, Thomas; Emens, Leisha A.; Hegde, Priti S.; Mellman, Ira; Turley, Shannon J.; Wilson, Mark S.; Mariathasan, Sanjeev; Molinero, Luciana; Merchant, Mark; West, Nathaniel R. 分享 收藏
Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumor 癌症相关成纤维细胞的空间定位和基质程序可促进人肺癌中的T细胞排斥 Grout, John A.; Sirven, Philemon; Leader, Andrew M.; Maskey, Shrisha; Hector, Eglantine; Puisieux, Isabelle; Steffan, Fiona; Cheng, Evan; Tung, Navpreet; Maurin, Mathieu; Vaineau, Romain; Karpf, Lea; Plaud, Martin; Begue, Anne-Laure; Ganesh, Koushik; Mesple, Jeremy; Casanova-Acebes, Maria; Tabachnikova, Alexandra; Keerthivasan, Shilpa; Lansky, Alona; Le Berichel, Jessica; Walker, Laura; Rahman, Adeeb H.; Gnjatic, Sacha; Girard, Nicolas; Lefevre, Marine; Damotte, Diane; Adam, Julien; Martin, Jerome C.; Wolf, Andrea; Flores, Raja M.; Beasley, Mary Beth; Pradhan, Rachana; Muller, Soren; Marron, Thomas U.; Turley, Shannon J.; Merad, Miriam; Kenigsberg, Ephraim; Salmon, Helene 分享 收藏
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Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1 通过胶原结构域结合受体LAIR1调节单核细胞和间质性肺巨噬细胞的稳态功能 Keerthivasan, Shilpa; Senbabaoglu, Yasin; Martinez-Martin, Nadia; Husain, Bushra; Verschueren, Erik; Wong, Anne; Yang, Yeqing Angela; Sun, Yonglian; Pham, Victoria; Hinkle, Trent; Oei, Yoko; Madireddi, Shravan; Corpuz, Racquel; Tam, Lucinda; Carlisle, Samantha; Roose-Girma, Merone; Modrusan, Zora; Ye, Zhengmao; Koerber, James T.; Turley, Shannon J. 分享 收藏
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IL-1R1-dependent signaling coordinates epithelial regeneration in response to intestinal damage Cox, Christian B.; Storm, Elaine E.; Kapoor, Varun N.; Chavarria-Smith, Joseph; Lin, David L.; Wang, Lifen; Li, Yun; Kljavin, Noelyn; Ota, Naruhisa; Bainbridge, Travis W.; Anderson, Keith; Roose-Girma, Merone; Warming, Soren; Arron, Joseph R.; Turley, Shannon J.; de Sauvage, Frederic J.; Campagne, Menno van Lookeren 分享 收藏
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Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues Kapoor, Varun N.; Muller, Soren; Keerthivasan, Shilpa; Brown, Markus; Chalouni, Cecile; Storm, Elaine E.; Castiglioni, Alessandra; Lane, Ryan; Nitschke, Maximilian; Dominguez, Claudia X.; Astarita, Jillian L.; Krishnamurty, Akshay T.; Carbone, Catherine B.; Senbabaoglu, Yasin; Wang, Amber W.; Wu, Xiumin; Cremasco, Viviana; Roose-Girma, Merone; Tam, Lucinda; Doerr, Jonas; Chen, Mark Z.; Lee, Wyne P.; Modrusan, Zora; Yang, Yeqing Angela; Bourgon, Richard; Sandoval, Wendy; Shaw, Andrey S.; de Sauvage, Frederic J.; Mellman, Ira; Moussion, Christine; Turley, Shannon J. 分享 收藏
Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer Desbois, Melanie; Udyavar, Akshata R.; Ryner, Lisa; Kozlowski, Cleopatra; Guan, Yinghui; Duerrbaum, Milena; Lu, Shan; Fortin, Jean-Philippe; Koeppen, Hartmut; Ziai, James; Chang, Ching-Wei; Keerthivasan, Shilpa; Plante, Marie; Bourgon, Richard; Bais, Carlos; Hegde, Priti; Daemen, Anneleen; Turley, Shannon; Wang, Yulei 分享 收藏
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