Gary H. Cohen - Publications, H-index & Citations

Gary H. Cohen

University of Pennsylvania

80H指数

283论文数

2.3W被引数

收录论文 117

发表时间

Unveiling the unique interaction mechanism of herpes simplex virus 2 glycoprotein C with C3b 揭示单纯疱疹病毒2型糖蛋白C与C3b的独特相互作用机制

Communications Biology

IF5.1

2026-08-04

OAAI

Moisés Hasim Rojas Rechy; Doina Atanasiu; Lauren M. Hook; Tina M. Cairns; Wan Ting Saw; Adam Cahill; Zilin Guo; Antonio N. Calabrese; Neil A. Ranson; Harvey M. Friedman; Gary H. Cohen; Juan Fontana

Boosting of vaginal HSV-2-specific B and T cell responses by intravaginal therapeutic immunization results in diminished recurrent HSV-2 disease

JOURNAL OF VIROLOGY

IF3.8

2023-09-28

OAAI

Bourne, Nigel; Keith, Celeste A.; Miller, Aaron L.; Pyles, Richard B.; Cohen, Gary; Milligan, Gregg N.

Rapid and accurate detection of herpes simplex virus type 2 using a low-cost electrochemical biosensor

CELL REPORTS PHYSICAL SCIENCE

IF7.3

2023-09-01

OAAI

de Lima, Lucas F.; Ferreira, Andre L.; Awasthi, Sita; Torres, Marcelo D. T.; Friedman, Harvey M.; Cohen, Gary H.; de Araujo, William R.; de la Fuente-Nunez, Cesar

A Trivalent HSV-2 gC2, gD2, gE2 Nucleoside-Modified mRNA-LNP Vaccine Provides Outstanding Protection in Mice against Genital and Non-Genital HSV-1 Infection, Comparable to the Same Antigens Derived from HSV-1

VIRUSES-BASEL

IF3.5

2023-06-30

OAAI

Egan, Kevin P.; Awasthi, Sita; Tebaldi, Giulia; Hook, Lauren M.; Naughton, Alexis M.; Fowler, Bernard T.; Beattie, Mitchell; Alameh, Mohamad-Gabriel; Weissman, Drew; Cohen, Gary H.; Friedman, Harvey M.

Novel Adjuvant S-540956 Targets Lymph Nodes and Reduces Genital Recurrences and Vaginal Shedding of HSV-2 DNA When Administered with HSV-2 Glycoprotein D as a Therapeutic Vaccine in Guinea Pigs

VIRUSES-BASEL

IF3.5

2023-05-10

OAAI

Awasthi, Sita; Onishi, Motoyasu; Lubinski, John M.; Fowler, Bernard T.; Naughton, Alexis M.; Hook, Lauren M.; Egan, Kevin P.; Hagiwara, Masaki; Shirai, Seiki; Sakai, Akiho; Nakagawa, Takayuki; Goto, Kumiko; Yoshida, Osamu; Stephens, Alisa J.; Choi, Grace; Cohen, Gary H.; Katayama, Kazufumi; Friedman, Harvey M.

Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion

VIRUSES-BASEL

IF3.5

2023-03-30

OAAI

Atanasiu, Doina; Saw, Wan Ting; Cairns, Tina M.; Friedman, Harvey M.; Eisenberg, Roselyn J.; Cohen, Gary H.

Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-11-07

OAAI

Gandy, Lauren A.; Canning, Ashley J.; Lou, Huan; Xia, Ke; He, Peng; Su, Guowei; Cairns, Tina; Liu, Jian; Zhang, Fuming; Linhardt, Robert J.; Cohen, Gary; Wang, Chunyu

Preventing neonatal herpes: Protection after maternal mRNA-lipid nanoparticle vaccination equals or exceeds that from prior maternal genital infection in murine models

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Desmond, Angela; LaTourette, Philip C.; Awasthi, Sita; Egan, Kevin P.; Hook, Lauren M.; Brice, Angela K.; Lubinski, John M.; Naughton, Alexis M.; Fowler, Bernard; Beattie, Mitchell; Pardi, Norbert; Cohen, Gary H.; Weissman, Drew; Friedman, Harvey M.

Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine

VIRUSES-BASEL

IF3.5

2022-03-05

OAAI

Hook, Lauren M.; Awasthi, Sita; Cairns, Tina M.; Alameh, Mohamad-Gabriel; Fowler, Bernard T.; Egan, Kevin P.; Sung, Molly M. H.; Weissman, Drew; Cohen, Gary H.; Friedman, Harvey M.

Using Split Luciferase Assay and Anti-Herpes Simplex Virus Glycoprotein Monoclonal Antibodies To Predict a Functional Binding Site between gD and gH/gL

JOURNAL OF VIROLOGY

IF3.8

2021-03-25

OAAI

Atanasiu, Doina; Saw, Wan Ting; Cairns, Tina M.; Eisenberg, Roselyn J.; Cohen, Gary H.

Localization of the Interaction Site of Herpes Simplex Virus Glycoprotein D (gD) on the Membrane Fusion Regulator, gH/gL

JOURNAL OF VIROLOGY

IF3.8

2020-09-29

OAAI

Cairns, Tina M.; Atanasiu, Doina; Saw, Wan Ting; Lou, Huan; Whitbeck, J. Charles; Ditto, Noah T.; Bruun, Birgitte; Browne, Helena; Bennett, Lucas; Wu, Chun; Krummenacher, Claude; Brooks, Benjamin D.; Eisenberg, Roselyn J.; Cohen, Gary H.

Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition

MOLECULES

IF4.6

2020-08-11

OAAI

Brooks, Benjamin D.; Closmore, Adam; Yang, Juechen; Holland, Michael; Cairns, Tina; Cohen, Gary H.; Bailey-Kellogg, Chris

An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection

PLOS PATHOGENS

IF4.9

2020-07-27

OAAI

Egan, Kevin P.; Hook, Lauren M.; Naughton, Alexis; Pardi, Norbert; Awasthi, Sita; Cohen, Gary H.; Weissman, Drew; Friedman, Harvey M.

Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopy 通过超分辨率显微镜揭示疱疹病毒糖蛋白在病毒包膜上的动态组织

PLOS PATHOGENS

IF4.9

2019-12-02

OAAI

Beilstein, Frauke; Cohen, Gary H.; Eisenberg, Roselyn J.; Nicolas, Valerie; Esclatine, Audrey; Pasdeloup, David

Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes

SCIENCE IMMUNOLOGY

IF16.3

2019-09-13

OAAI

Awasthi, Sita; Hook, Lauren M.; Pardi, Norbert; Wang, Fushan; Myles, Arpita; Cancro, Michael P.; Cohen, Gary H.; Weissman, Drew; Friedman, Harvey M.

Surface Plasmon Resonance Reveals Direct Binding of Herpes Simplex Virus Glycoproteins gH/gL to gD and Locates a gH/gL Binding Site on gD

JOURNAL OF VIROLOGY

IF3.8

2019-08-01

OAAI

Cairns, Tina M.; Ditto, Noah T.; Atanasiu, Doina; Lou, Huan; Brooks, Benjamin D.; Saw, Wan Ting; Eisenberg, Roselyn J.; Cohen, Gary H.

Using Antibodies and Mutants To Localize the Presumptive gH/gL Binding Site on Herpes Simplex Virus gD

JOURNAL OF VIROLOGY

IF3.8

2018-12-15

OAAI

Atanasiu, Doina; Saw, Wan Ting; Lazear, Eric; Whitbeck, J. Charles; Cairns, Tina M.; Lou, Huan; Eisenberg, Roselyn J.; Cohen, Gary H.

Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging

PLOS PATHOGENS

IF4.9

2017-06-14

OAAI

Cairns, Tina M.; Ditto, Noah T.; Lou, Huan; Brooks, Benjamin D.; Atanasiu, Doina; Eisenberg, Roselyn J.; Cohen, Gary H.

Prophylactic Herpes Simplex Virus 2 (HSV-2) Vaccines Adjuvanted with Stable Emulsion and Toll-Like Receptor 9 Agonist Induce a Robust HSV-2-Specific Cell-Mediated Immune Response, Protect against Symptomatic Disease, and Reduce the Latent Viral Reservoir

JOURNAL OF VIROLOGY

IF3.8

2017-05-01

OAAI

Hensel, Michael T.; Marshall, Jason D.; Dorwart, Michael R.; Heeke, Darren S.; Rao, Eileen; Tummala, Padmaja; Yu, Li; Cohen, Gary H.; Eisenberg, Roselyn J.; Sloan, Derek D.

Nasal Immunization Confers High Avidity Neutralizing Antibody Response and Immunity to Primary and Recurrent Genital Herpes in Guinea Pigs 鼻免疫赋予豚鼠高亲和力中和抗体反应和对原发性和复发性生殖器疱疹的免疫力

FRONTIERS IN IMMUNOLOGY

IF5.9

2016-12-26

OAAI

Persson, Josefine; Zhang, Yuan; Olafsdottir, Thorunn A.; Thorn, Karolina; Cairns, Tina M.; Wegmann, Frank; Sattentau, Quentin J.; Eisenberg, Roselyn J.; Cohen, Gary H.; Harandi, Ali M.

研究方向