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E

E. John Wherry

University of Pennsylvania
H指数:142
被引数:10.8万

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荣誉奖项

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Bispecific dual T cell agonist invikafusp alfa in solid tumors: the phase 1/2 START-001 trial

双特异性双T细胞激动剂invikafusp alfa在实体瘤中的研究：第1/2期START-001试验

Nature Medicine
IF50
2026-10-230
PRE
Ryan J. Sullivan; Nicholas P. Tschernia; Claire F. Friedman; Mercedes Herrera; Guru P. Sonpavde; Kai He; Antoine Italiano; Aurélien Marabelle; Matthieu Roulleaux-Dugage; François-Xavier Danlos; Elena Garralda Cabanas; Alberto Hernando-Calvo; Manuel Pedregal; Aparna Parikh; Gopakumar Iyer; Ahmed Zakari; E. John Wherry; Jeffrey Schlom; Renee N. Donahue; Shannon McCue; Sharon Cross; Karunya Srinivasan; Lisa Benincosa; Madan Katragadda; Zhenming Shun; Kevin Chin; Zhen Su; Ke Liu; Lillian L. Siu; James L. Gulley
SARS-CoV-2-specific monoclonal antibody AER002 in Long COVID: an exploratory randomized phase 2a mechanistic trial

长新冠中SARS-CoV-2特异性单克隆抗体AER002：一项探索性随机2a期机制试验

Nature Communications
IF15.7
2026-09-300
OAAI
Michael J. Peluso; Dylan Ryder; Thomas Dalhuisen; Danny Hoi Tsun Chu; Meghann C. Williams; Antonio E. Rodriguez; Brian H. LaFranchi; Joanna Vinden; Emily A. Fehrman; Beatrice Huang; Rebecca Hoh; Kofi A. Asare; Kathleen Bellon Pizarro; Mohammad Sofiqur Rahman; Emilio de Narvaez; Mark M. Painter; E. John Wherry; Zoe N. Swank; Louise L. Hansen; David R. Walt; Yoshinori Fukazawa; Anisha Sekar; Steven E. Bellan; Holly Tieu; Josephat Asiago; Prakash Bhuyan; Rajeev Venkayya; Robert R. Flavell; Henry VanBrocklin; J. Daniel Kelly; Priscilla Y. Hsue; Matthew S. Durstenfeld; Peter W. Hunt; Leonard Calabrese; Ma Somsouk; Jeffrey N. Martin; David V. Glidden; Amelia N. Deitchman; Timothy J. Henrich; Steven G. Deeks
Potent type-specific de novo antibodies complement broadly reactive imprinted antibodies in immune responses to SARS-CoV-2 variants

针对SARS-CoV-2变异株的强效型特异性从头抗体与广泛反应的原初抗体在免疫应答中互补

Nature Immunology
IF27.6
2026-08-140
OA
Timothy S. Johnston; Shuk Hang Li; Mark M. Painter; Divya Swaminathan; Reilly K. Atkinson; Bernadeta Dadonaite; Shuishu Wang; Naomi R. Douek; Lucas Kampman; Robin Schlesinger; Rachel Kazmierski; Bob C. Lin; Leonid A. Serebryannyy; Haijuan Du; Amy R. Henry; Sarah C. Smith; Farida Laboune; I-Ting Teng; Lingshu Wang; Nicole A. Doria-Rose; Chaim A. Schramm; Theodore C. Pierson; Tongqing Zhou; Jesse D. Bloom; E. John Wherry; Scott E. Hensley; Daniel C. Douek
In vivo reprogramming of cytotoxic effector CD8 T cells via fractalkine-conjugated mRNA-LNPs

通过 fractalkine 偶联的 mRNA-LNP 对细胞毒性效应 CD8 T 细胞进行体内重编程

Science Immunology
IF16.3
2026-05-080
PRE
Angela R. Corrigan; Shin Foong Ngiow; Maura Statzu; Amie Albertus; M. Betina Pampena; Jayme M. L. Nordin; Stephen D. Carro; Justin Harper; Rachelle L. Stammen; Jennifer Wood; Houping Ni; Justin Su; Marziyeh Hajialyani; Vladimir V. Shuvaev; Victor Alcalde; Mohammed-Alkhatim A. Ali; Jacob T. Hamilton; Rajesvaran Ramalingam; Vincent H. Wu; Mirko Paiardini; Drew Weissman; E. John Wherry; Edward F. Kreider; Michael R. Betts
Rewiring STAT signaling from the cell surface with Trikine immunotherapeutics

使用Trikine免疫治疗剂重塑细胞表面的STAT信号通路

Science
IF45.8
2026-02-190
PRE
Grayson E. Rodriguez; Yang Zhao; Yoko Nishiga; Frank Peprah; Jiao Shen; Gita C. Abhiraman; Masato Ogishi; Chenyu Zhang; Justin Saco; Deepa Waghray; Mamatha Serasanambati; Leonel Torres; Brandon W. Simone; Leon Su; Steven C. Wilson; Aerin Yang; Qinli Sun; Lora Picton; Robert A. Saxton; Vidit Bhandarkar; Madeline J. Lee; Elizabeth Andrews; Hua Jiang; Matthias Obenaus; Michelle Yen; Tavus Atajanova; Catherine A. Blish; Stefani Spranger; E. John Wherry; Amanda Kirane; Antoni Ribas; David H. Raulet; Anusha Kalbasi; Stephanie K. Dougan; Michael Dougan; Julien Sage; K. Christopher Garcia
Single-cell profiling reveals diverse γδ T cell subsets in ulcerative colitis

单细胞分析揭示溃疡性结肠炎中不同的 γ δ T细胞亚群

Science Immunology
IF16.3
2026-02-060
PRE
Lena S. Mayer; Jakob Arnold; Felix Roettele; Nadine Reuter; Ajinkya Pattekar; Takuya Ohtani; Mariana M. Ribeiro; Rebecca Siwicki; Kerstin Bruder; David Obwegs; Elin Stahl; Sarah Buechel; Natascha Roehlen; Julia Kolter; Zohreh Mansoori Moghadam; Ahmed Alaswad; Zhibek Zhumalidova; Guang Li; Xinjuan Liu; Yang Li; Amit Singh; Jose Villacorta Hidalgo; Maria D. Paraskevopoulou; Vijay Yajnik; Julius Juarez; Yue Ren; Hongzhe Li; E. John Wherry; James D. Lewis; Gary D. Wu; Meenakshi Bewtra; Vesselin T. Tomov; Robert Thimme; Bertram Bengsch; Peter Hasselblatt; Simone Picelli; Maike Hofmann; Sagar
Chimeric antigen receptor T cells against the IGHV4-34 B cell receptor specifically eliminate neoplastic and autoimmune B cells

针对IGHV4-34 b细胞受体的嵌合抗原受体T细胞特异性消除肿瘤性和自身免疫性b细胞

Science Translational Medicine
IF14.6
2026-02-040
PRE
Ivan J. Cohen; Audrey C. Bochi-Layec; Jean Lemoine; Scott Jenks; Pedram Bayat; Ki Hyun Kim; Huiwu Zhao; Ositadimma Ugwuanyi; Federico Stella; Guido Ghilardi; Giulia Gabrielli; Sarah McCuaig; Anastasia Iatrou; Elisavet Vlachonikola; Maria Karipidou; Eleni Bouziani; David Espie; Ranjani Ramasubramanian; Andreas Agathangelidis; Aditya Bhosale; Luca Paruzzo; Giovanni Medico; Bronte Kolar; Regina Bugrovsky; Puneeth Guruprasad; Li-Ping Wang; Jaryse Harris; Evgeny Arons; Yunlin Zhang; Raymone Pajarillo; Portia A. Kreiger; Chi-Ping Day; S. Cenk Sahinalp; Chih Hao Wu; Alessia Santi; Bria Fulmer; Marcos Cases; Matthew B. Palmer; Patrizia Porazzi; E. John Wherry; Robert J. Kreitman; Enrico Tiacci; Sokratis A. Apostolidis; Edward M. Behrens; Vijay Bhoj; Ignacio Sanz; Giorgio Inghirami; Stephen J. Schuster; Paolo Ghia; Kostas Stamatopoulos; Marco Ruella
Publisher Correction: Tissue-resident exhausted and memory CD8+ T cells have distinct ontogeny, function and roles in disease

出版商更正: 组织驻留的耗竭和记忆CD8 T细胞在疾病中具有独特的个体发育，功能和作用

Nature Immunology
IF27.6
2026-01-130
OAAI
Simone L. Park; Mark M. Painter; Sasikanth Manne; Victor Alcalde; Maura McLaughlin; Matthew A. Sullivan; Divij Mathew; Leonel Torres; Yinghui J. Huang; David B. Reeg; Naomi R. Douek; Trenton Campos; Max Klapholz; Maria A. Cardenas; Victoria Fang; Shin Foong Ngiow; Wumesh KC; Rishi R. Goel; Amy E. Baxter; Jennifer E. Wu; Melody Tan; Corbett T. Berry; Christoph T. Ellebrecht; Alexander C. Huang; Emily Papazian; Ying Liu; Karthik Rajasekaran; Robert M. Brody; Erica R. Thaler; Devraj Basu; Ahmed Diab; Josephine R. Giles; E. John Wherry
Tissue-resident exhausted and memory CD8+ T cells have distinct ontogeny, function and role in disease

组织驻留的耗竭型和记忆型CD8+ T细胞具有不同的发生、功能及在疾病中的角色。

Nature Immunology
IF27.6
2025-12-290
PRE
Simone L. Park; Mark M. Painter; Sasikanth Manne; Victor Alcalde; Maura McLaughlin; Matthew A. Sullivan; Divij Mathew; Leonel Torres; Yinghui J. Huang; David B. Reeg; Naomi R. Douek; Trenton Campos; Max Klapholz; Maria A. Cardenas; Victoria Fang; Shin Foong Ngiow; Wumesh KC; Rishi R. Goel; Amy E. Baxter; Jennifer E. Wu; Melody Tan; Corbett T. Berry; Christoph T. Ellebrecht; Huang C. Alexander; Emily Papazian; Ying Liu; Karthik Rajasekaran; Robert M. Brody; Erica R. Thaler; Devraj Basu; Ahmed Diab; Josephine R. Giles; E. John Wherry
Guidelines for T cell nomenclature

T细胞命名指南

Nature Reviews Immunology
IF60.9
2025-11-180
OAAI
David Masopust; Amit Awasthi; Rémy Bosselut; David G. Brooks; Marcus Buggert; Kenji Chamoto; Weiguo Cui; Chen Dong; Donna L. Farber; Thomas Gebhardt; Carmen Gerlach; Ananda Goldrath; Philip D. Greenberg; J. Scott Hale; Adrian Hayday; Dirk Homann; Matteo Iannacone; Stephen C. Jameson; Marc K. Jenkins; Nikhil S. Joshi; Susan M. Kaech; Axel Kallies; Alice O. Kamphorst; Mark H. Kaplan; Paul Klenerman; Marco Künzli; Antonio Lanzavecchia; Georg M. Lauer; Enrico Lugli; Andrew D. Luster; Laura K. Mackay; M. Juliana McElrath; Scott N. Mueller; Zaza Ndhlovu; Thumbi Ndung’u; Pamela S. Ohashi; Annette Oxenius; Giuseppe Pantaleo; Marion Pepper; Louis J. Picker; Clare F. Quarnstrom; Gustavo Reyes-Terán; Mario Roederer; Pamela C. Rosato; Gonzalo Salgado-Montes de Oca; Federica Sallusto; Ton N. Schumacher; Daniella M. Schwartz; Eui-Cheol Shin; Andrew G. Soerens; Daniela S. Thommen; Vaiva Vezys; João P. B. Viola; Bruce D. Walker; Tania H. Watts; Casey T. Weaver; E. John Wherry; Hai-Hui Xue; Ben Youngblood; Rafi Ahmed
Thrombospondin-1–CD47 signaling contributes to the development of T cell exhaustion in cancer

Thrombospondin-1-CD47信号有助于癌症中T细胞耗竭的发展

Nature Immunology
IF27.6
2025-11-170
PRE
Chien-Huan Weng; Anais Assouvie; Lauren Dong; Jean-Christophe Beltra; Sadna Budhu; Levi Mangarin; Yacine Marouf; Lucia Morgado-Palacin; Cailian Liu; Sébastien Monette; Jonathan F. Khan; Isabell Schulze; Dmitriy Zamarin; Linda Hamadene; Fadi Samaan; Daniel Hirschhorn; Stephane Pourpe; David Schröder; Roberta Zappasodi; Pamela M. Holland; Niroshana Anandasabapathy; E. John Wherry; Jedd D. Wolchok; Taha Merghoub
Immune remodeling in CSF and tumor predicts response to CAR T therapy in glioblastoma

脑脊液和肿瘤中的免疫重塑预测胶质母细胞瘤对CAR T疗法的反应

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Chafamo, Daniel; Freeburg, Nelson; Gopikrishna, Gayathri Konanur; Peng, Jacqueline; Lamrani, Lamia; Hicks, Kelly; Ekwegbara, Christina; Bawden, Emma; Waterfall, Joshua; Fuentealba, Jaime; Alcantara, Marion; Barrett, David; Macia, Camilla; Yin, Melinda; Carpenter, Erica; Wherry, Edward; Amigorena, Sebastian; Fraietta, Joseph; Nasrallah, MacLean; Bagley, Stephen; O'rourke, Donald; Binder, Zev; Alanio, Cecile; Silverbush, Dana
Representing immune profiles with self-supervised set representation learning
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Lee, Matthew Eric; Ionita, Matei; Kim, Jaesik; Lee, Jonghyun; Huang, Yidi; Nam, Yonghyun; McKeague, Michelle L.; Fang, Victoria; Apostolidis, Sokratis A.; Mathew, Divij; Shwetank; Pattekar, Ajinkya; Rangwala, Zahabia; Huang, Alexander; Bar-Or, Amit; Abramoff, Benjamin; Meyer, Nuala; Rhee, Rennie; Schuster, Stephen; Maseda, Damian; Greenplate, Allison R.; Kim, Dokyoon; Wherry, E. John
Online resources from the Allen institute for immunology: the human immune health atlas and human immune system explorer platform

艾伦免疫学研究所的在线资源: 人类免疫健康地图集和人类免疫系统资源管理器平台

JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Graybuck, Lucas T.; La France, Christian; Howard, Nicole; Liang, Jessica; Kelsey, Autumn; Okada, Lauren; Thomson, Zachary; Gong, Qiuyu; Sharma, Mehul; Glass, Marla; Chander, Aishwarya; Singh, Mansi; Zaim, Samir Rachid; Peng, Tao; Genge, Palak; Henderson, Katherine; Dornisch, Elisabeth; Layton, Erik; Wittig, Peter; Heubeck, Alex; Mukuka, Nelson; Reading, Julian; Roll, Charles; Hernandez, Veronica; Parthasarathy, Vaishnavi; Stuckey, Tyanna; Musgrove, Blessing; Swanson, Elliott; Lord, Cara; Weiss, Morgan; Phalen, Cole; Mettey, Regina; Lee, Kevin; Johanneson, John; Kawelo, Erin; Garber, Jessica; Krishnan, Upaasana; Aggoune, Yousef; Ambrose, Madeline; Beaubien, Aldan; Harvey, James; Inala, Neelima; Johnson, Ed; Kinsey, Melissa; Mariz, Paul; Pister, Stark; Subramanian, Sathya; Tereshchenko, Vitalii; Vetto, Anne; Smithmeyer, Megan; Wherry, E. John; Vella, Laura; Henrickson, Sarah Emily; Kopp, Mackenzie; Savage, Adam; Becker, Lynne A.; Coffey, Ernie; Goronzy, Jorg; Speake, Cate; Bumol, Thomas; Goldrath, Ananda; Torgerson, Troy R.; Li, Xiao-jun; Buckner, Jane H.; Skene, Peter; Gustafson, Claire E.; Meijer, Paul

研究方向

暂未获取到该数据
S
Sasikanth Manne
H 指数:39论文数:111被引数:1.2万
R
Rafi Ahmed
H 指数:162论文数:771被引数:10.8万
J
Josephine R. Giles
H 指数:37论文数:101被引数:1.3万
D
Divij Mathew
H 指数:36论文数:105被引数:9,482
S
Scott E. Hensley
H 指数:63论文数:291被引数:1.7万
L
Laura A. Vella
H 指数:36论文数:91被引数:8,170
R
Ramin S. Herati
H 指数:37论文数:117被引数:9,702
M
Michael R. Betts
H 指数:86论文数:296被引数:3.1万
陈则宇 封面图
陈则宇
H 指数:32论文数:126被引数:8,316
A
Allison R. Greenplate
H 指数:41论文数:126被引数:1.1万