未登录 Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes Yin, Jiang-An; Frick, Lukas; Scheidmann, Manuel C.; Liu, Tingting; Trevisan, Chiara; Dhingra, Ashutosh; Spinelli, Anna; Wu, Yancheng; Yao, Longping; Vena, Dalila Laura; Knapp, Britta; Guo, Jingjing; De Cecco, Elena; Ging, Kathi; Armani, Andrea; Oakeley, Edward J.; Nigsch, Florian; Jenzer, Joel; Haegele, Jasmin; Pikusa, Michal; Taeger, Joachim; Rodriguez-Nieto, Salvador; Bouris, Vangelis; Ribeiro, Rafaela; Baroni, Federico; Bedi, Manmeet Sakshi; Berry, Scott; Losa, Marco; Hornemann, Simone; Kampmann, Martin; Pelkmans, Lucas; Hoepfner, Dominic; Heutink, Peter; Aguzzi, Adriano 分享 收藏
Valhidepsin Lipopeptides from Chromobacterium vaccinii: Structures, Biosynthesis, and Coregulation with FR900359 Production Pistorius, Dominik; Buntin, Kathrin; Richard, Etienne; Rust, Michael; Bouquet, Caroline; Wollbrett, Severine; Weber, Eric; Dietschin, Daniele; Bruccoleri, Robert; Oakeley, Edward; Petersen, Frank 分享 收藏
Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity 亚胺还原酶的活性和立体选择性的机器定向进化 Ma, Eric J.; Siirola, Elina; Moore, Charles; Kummer, Arkadij; Stoeckli, Markus; Faller, Michael; Bouquet, Caroline; Eggimann, Fabian; Ligibel, Mathieu; Dan Huynh; Cutler, Geoffrey; Siegrist, Luca; Lewis, Richard A.; Acker, Anne-Christine; Freund, Ernst; Koch, Elke; Vogel, Markus; Schlingensiepen, Holger; Oakeley, Edward J.; Snajdrova, Radka 分享 收藏
Gene-signature-derived IC50s/EC50s reflect the potency of causative upstream targets and downstream phenotypes Renner, Steffen; Bergsdorf, Christian; Bouhelal, Rochdi; Koziczak-Holbro, Magdalena; Amati, Andrea Marco; Techer-Etienne, Valerie; Flotte, Ludivine; Reymann, Nicole; Kapur, Karen; Hoersch, Sebastian; Oakeley, Edward James; Schuffenhauer, Ansgar; Gubler, Hanspeter; Lounkine, Eugen; Farmer, Pierre 分享 收藏
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An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation Syndrome Sic, Heiko; Speletas, Matthaios; Cornacchione, Vanessa; Seidl, Maximillian; Beibel, Martin; Linghu, Bolan; Yang, Fan; Sevdali, Eirini; Germenis, Anastasios E.; Oakeley, Edward J.; Vangrevelinghe, Eric; Sailer, Andreas W.; Traggiai, Elisabetta; Gram, Hermann; Eibel, Hermann 分享 收藏
Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families Ngcungcu, Thandiswa; Oti, Martin; Sitek, Jan C.; Haukanes, Bjorn I.; Linghu, Bolan; Bruccoleri, Robert; Stokowy, Tomasz; Oakeley, Edward J.; Yang, Fan; Zhu, Jiang; Sultan, Marc; Schalkwijk, Joost; van Vlijmen-Willems, Ivonne M. J. J.; von der Lippe, Charlotte; Brunner, Han G.; Ersland, Kari M.; Grayson, Wayne; Buechmann-Moller, Stine; Sundnes, Olav; Nirmala, Nanguneri; Morgan, Thomas M.; van Bokhoven, Hans; Steen, Vidar M.; Hull, Peter R.; Szustakowski, Joseph; Staedtler, Frank; Zhou, Huiqing; Fiskerstrand, Torunn; Ramsay, Michele 分享 收藏
Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis (vol 100, pg 323, 2017) Macia, Maxence S.; Halbritter, Jan; Delous, Marion; Bredrup, Cecilie; Gutter, Arthur; Filhol, Emilie; Mellgren, Anne E. C.; Leh, Sabine; Bizet, Albane; Braun, Daniela A.; Gee, Heon Y.; Silbermann, Flora; Henry, Charline; Krug, Pauline; Bole-Feysot, Christine; Nitschke, Patrick; Joly, Dominique; Nicoud, Philippe; Paget, Andre; Haugland, Heidi; Brackmann, Damien; Ahmet, Nayir; Sandford, Richard; Cengiz, Nurcan; Knappskog, Per M.; Boman, Helge; Linghu, Bolan; Yang, Fan; Oakeley, Edward J.; Saint Mezard, Pierre; Sailer, Andreas W.; Johansson, Stefan; Rodahl, Eyvind; Saunier, Sophie; Hildebrandt, Friedhelm; Benmerah, Alexandre 分享 收藏
Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis Macia, Maxence S.; Halbritter, Jan; Delous, Marion; Bredrup, Cecilie; Gutter, Arthur; Filhol, Emilie; Mellgren, Anne E. C.; Leh, Sabine; Bizet, Albane; Braun, Daniela A.; Gee, Heon Y.; Sibermann, Flora; Henry, Charline; Krug, Pauline; Bole-Feysot, Christine; Nitschke, Patrick; Joly, Dominique; Nicoud, Philippe; Paget, Andre; Haugland, Heidi; Brackmann, Damien; Ahmet, Nayir; Sandford, Richard; Cengiz, Nurcan; Knappskog, Per M.; Boman, Helge; Linghu, Bolan; Yang, Fan; Oakeley, Edward J.; Saint Mezard, Pierre; Sailer, Andreas W.; Johansson, Stefan; Rodahl, Eyvind; Saunier, Sophie; Hildebrandt, Friedhelm; Benmerah, Alexandre 分享 收藏
CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations Brykczynska, Urszula; Pecho-Vrieseling, Eline; Thiemeyer, Anke; Klein, Jessica; Fruh, Isabelle; Doll, Thierry; Manneville, Carole; Fuchs, Sascha; Iazeolla, Mariavittoria; Beibel, Martin; Roma, Guglielmo; Naumann, Ulrike; Kelley, Nicholas; Oakeley, Edward J.; Mueller, Matthias; Gomez-Mancilla, Baltazar; Buhler, Marc; Tabolacci, Elisabetta; Chiurazzi, Pietro; Neri, Giovanni; Bouwmeester, Tewis; Di Giorgio, Francesco Paolo; Fodor, Barna D. 分享 收藏
Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization Bizet, Albane A.; Becker-Heck, Anita; Ryan, Rebecca; Weber, Kristina; Filhol, Emilie; Krug, Pauline; Halbritter, Jan; Delous, Marion; Lasbennes, Marie-Christine; Linghu, Bolan; Oakeley, Edward J.; Zarhrate, Mohammed; Nitschke, Patrick; Garfa-Traore, Meriem; Serluca, Fabrizio; Yang, Fan; Bouwmeester, Tewis; Pinson, Lucile; Cassuto, Elisabeth; Dubot, Philippe; Elshakhs, Neveen A. Soliman; Sahel, Jose A.; Salomon, Remi; Drummond, Iain A.; Gubler, Marie-Claire; Antignac, Corinne; Chibout, Salandine; Szustakowski, Joseph D.; Hildebrandt, Friedhelm; Lorentzen, Esben; Sailer, Andreas W.; Benmerah, Alexandre; Saint-Mezard, Pierre; Saunier, Sophie 分享 收藏
Molecular mechanisms of D-cycloserine in facilitating fear extinction: insights from RNAseq Malan-Mueller, Stefanie; Fairbairn, Lorren; Daniels, Willie M. U.; Dashti, Mahjoubeh Jalali Sefid; Oakeley, Edward J.; Altorfer, Marc; Kidd, Martin; Seedat, Soraya; Gamieldien, Junaid; Hemmings, Sian Megan Joanna 分享 收藏
Transcriptome diversity among rice root types during asymbiosis and interaction with arbuscular mycorrhizal fungi Gutjahr, Caroline; Sawers, Ruairidh J. H.; Marti, Guillaume; Andres-Hernandez, Liliana; Yang, Shu-Yi; Casieri, Leonardo; Angliker, Herbert; Oakeley, Edward J.; Wolfender, Jean-Luc; Abreu-Goodger, Cei; Paszkowski, Uta 分享 收藏
Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon Decatransin，一种新的天然产物，可抑制Sec61/SecYEG易位的蛋白质易位 Junne, Tina; Wong, Joanne; Studer, Christian; Aust, Thomas; Bauer, Benedikt W.; Beibel, Martin; Bhullar, Bhupinder; Bruccoleri, Robert; Eichenberger, Juerg; Estoppey, David; Hartmann, Nicole; Knapp, Britta; Krastel, Philipp; Melin, Nicolas; Oakeley, Edward J.; Oberer, Lukas; Riedl, Ralph; Roma, Guglielmo; Schuierer, Sven; Petersen, Frank; Tallarico, John A.; Rapoport, Tom A.; Spiess, Martin; Hoepfner, Dominic 分享 收藏
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium 测序质量控制联盟对rna-seq准确性，可重复性和信息含量的全面评估 Su, Zhenqiang; Labaj, Pawel P.; Li, Sheng; Thierry-Mieg, Jean; Thierry-Mieg, Danielle; Shi, Wei; Wang, Charles; Schroth, Gary P.; Setterquist, Robert A.; Thompson, John F.; Jones, Wendell D.; Xiao, Wenzhong; Xu, Weihong; Jensen, Roderick V.; Kelly, Reagan; Xu, Joshua; Conesa, Ana; Furlanello, Cesare; Gao, Hanlin; Hong, Huixiao; Jafari, Nadereh; Letovsky, Stan; Liao, Yang; Lu, Fei; Oakeley, Edward J.; Peng, Zhiyu; Praul, Craig A.; Santoyo-Lopez, Javier; Scherer, Andreas; Shi, Tieliu; Smyth, Gordon K.; Staedtler, Frank; Sykacek, Peter; Tan, Xin-Xing; Thompson, E. Aubrey; Vandesompele, Jo; Wang, May D.; Wang, Jian; Wolfinger, Russell D.; Zavadil, Jiri; Auerbach, Scott S.; Bao, Wenjun; Binder, Hans; Blomquist, Thomas; Brilliant, Murray H.; Bushel, Pierre R.; Cain, Weimin; Catalano, Jennifer G.; Chang, Ching-Wei; Chen, Tao; Chen, Geng; Chen, Rong; Chierici, Marco; Chu, Tzu-Ming; Clevert, Djork-Arne; Deng, Youping; Derti, Adnan; Devanarayan, Viswanath; Dong, Zirui; Dopazo, Joaquin; Du, Tingting; Fang, Hong; Fang, Yongxiang; Fasold, Mario; Fernandez, Anita; Fischer, Matthias; Furio-Tari, Pedro; Fuscoe, James C.; Caiment, Florian; Gaj, Stan; Gandara, Jorge; Gao, Huan; Ge, Weigong; Gondo, Yoichi; Gong, Binsheng; Gong, Meihua; Gong, Zhuolin; Green, Bridgett; Guo, Chao; Guo, Lei; Guo, Li-Wu; Hadfield, James; Hellemans, Jan; Hochreiter, Sepp; Jia, Meiwen; Jian, Min; Johnson, Charles D.; Kay, Suzanne; Kleinjans, Jos; Lababidi, Samir; Levy, Shawn; Li, Quan-Zhen; Li, Li; Li, Li; Li, Peng; Li, Yan; Li, Haiqing; Li, Jianying; Li, Shiyong; Lin, Simon M.; Lopez, Francisco J.; Lu, Xin; Luo, Heng; Ma, Xiwen; Meehan, Joseph; Megherbi, Dalila B.; Mei, Nan; Mu, Bing; Ning, Baitang; Pandey, Akhilesh; Perez-Florido, Javier; Perkins, Roger G.; Peters, Ryan; Phan, John H.; Pirooznia, Mehdi; Qian, Feng; Qing, Tao; Rainbow, Lucille; Rocca-Serra, Philippe; Sambourg, Laure; Sansone, Susanna-Assunta; Schwartz, Scott; Shah, Ruchir; Shen, Jie; Smith, Todd M.; Stegle, Oliver; Stralis-Pavese, Nancy; Stupka, Elia; Suzuki, Yutaka; Szkotnicki, Lee T.; Tinning, Matthew; Tu, Bimeng; van Deft, Joost; Vela-Boza, Alicia; Venturini, Elisa; Walker, Stephen J.; Wan, Liqing; Wang, Wei; Wang, Jinhui; Wang, Jun; Wieben, Eric D.; Willey, James C.; Wu, Po-Yen; Xuan, Jiekun; Yang, Yong; Ye, Zhan; Yin, Ye; Yu, Ying; Yuan, Yate-Ching; Zhang, John; Zhang, Ke K.; Zhang, Wenqian; Zhang, Wenwei; Zhang, Yanyan; Zhao, Chen; Zheng, Yuanting; Zhou, Yiming; Zumbo, Paul; Tong, Weida; Kreil, David P.; Mason, Christopher E.; Shi, Leming 分享 收藏
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions Hoepfner, Dominic; Helliwell, Stephen B.; Sadlish, Heather; Schuierer, Sven; Filipuzzi, Ireos; Brachat, Sophie; Bhullar, Bhupinder; Plikat, Uwe; Abraham, Yann; Altorfer, Marc; Aust, Thomas; Baeriswyl, Lukas; Cerino, Raffaele; Chang, Lena; Estoppey, David; Eichenberger, Juerg; Frederiksen, Mathias; Hartmann, Nicole; Hohendahl, Annika; Knapp, Britta; Krastel, Philipp; Melin, Nicolas; Nigsch, Florian; Oakeley, Edward J.; Petitjean, Virginie; Petersen, Frank; Riedl, Ralph; Schmitt, Esther K.; Staedtler, Frank; Studer, Christian; Tallarico, John A.; Wetzel, Stefan; Fishman, Mark C.; Porter, Jeffrey A.; Movva, N. Rao 分享 收藏
Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells Hannedouche, Sebastien; Beck, Valerie; Leighton-Davies, Juliet; Beibel, Martin; Roma, Guglielmo; Oakeley, Edward J.; Lannoy, Vincent; Bernard, Jerome; Hamon, Jacques; Barbieri, Samuel; Preuss, Inga; Lasbennes, Marie-Christine; Sailer, Andreas W.; Suply, Thomas; Seuwen, Klaus; Parker, Christian N.; Bassilana, Frederic 分享 收藏
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome Thomson, John P.; Lempiaeinen, Harri; Hackett, Jamie A.; Nestor, Colm E.; Mueller, Arne; Bolognani, Federico; Oakeley, Edward J.; Schuebeler, Dirk; Terranova, Remi; Reinhardt, Diana; Moggs, Jonathan G.; Meehan, Richard R. 分享 收藏
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