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Combined CXCR-4 Inhibition with Novel Agent GPC-100 (burixafor) and Beta 2 Adrenergic Receptor Blockade Enhances Cytarabine Response for Acute Myeloid Leukemia Blasts on Stroma 联合使用CXCR-4抑制剂新型药物GPC-100（burixafor）和β2肾上腺素受体阻滞剂可增强急性髓系白血病细胞在基质中的阿糖胞苷反应。 Tang, Yueming; Braun, Adam; von Behren, Zachary; Wu, Jieya; Haley, Caitlyn; Zhang, Chunxiao; Loera, Brenda; Cardarelli, Pina M.; Caculitan, Nina; Chien, Sylvia; Dai, Jin; Oehler, Vivian G.; Zhang, Jianying; Marcucci, Guido; Becker, Pamela S. 分享 收藏
Toward optimizing CXCR4 inhibition with beta adrenergic blockade to enhance chemotherapy response in acute myeloid leukemia Loera, Brenda; Zhang, Chunxiao; Cardarelli, Pina M.; Caculitan, Nina G.; Chien, Sylvia; Dai, Jin; Oehler, Vivian G.; Zhang, Jianying; Marcucci, Guido; Becker, Pamela S. 分享 收藏
DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody-Drug Conjugate Modality Sivaprakasam, Prasanna; McDonald, Ivar; Iwuagwu, Christiana; Chowdari, Naidu S.; Peese, Kevin M.; Langley, David R.; Cheng, Heng; Luzung, Michael R.; Schmidt, Michael A.; Zheng, Bin; Tan, Yichen; Cho, Patricia; Rakshit, Souvik; Lakshminarasimhan, Thirumalai; Guturi, Sivakrishna; Kanagavel, Kishorekumar; Kanusu, Umamaheswararao; Niyogi, Ankita G.; Sidhar, Somprabha; Vaidyanathan, Rajappa; Eastgate, Martin D.; Kotapati, Srikanth; Deshpande, Madhura; Pan, Chin; Cardarelli, Pina M.; Xie, Chunshan; Rao, Chetana; Holder, Patrick; Sarma, Ganapathy; Vite, Gregory; Gangwar, Sanjeev 分享 收藏
Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates Chowdari, Naidu S.; Zhang, Yong; McDonald, Ivar; Johnson, Walter; Langley, David R.; Sivaprakasam, Prasanna; Mate, Robert; Huynh, Tram; Kotapati, Srikanth; Deshpande, Madhura; Pan, Chin; Menezes, Daniel; Wang, Yichong; Rao, Chetana; Sarma, Ganapathy; Warrack, Bethanne M.; Rangan, Vangipuram S.; Mei-Chen, Sung; Cardarelli, Pina; Deshpande, Shrikant; Passmore, David; Rampulla, Richard; Mathur, Arvind; Borzilleri, Robert; Rajpal, Arvind; Vite, Gregory; Gangwar, Sanjeev 分享 收藏
Synthesis and Biological Evaluation of a Carbamate-Containing Tubulysin Antibody-Drug Conjugate Cheng, Heng; Cong, Qiang; Dervin, Dan; Stevens, Alice; Vemuri, Kavitha; Huber, Mary; Juliano, Jennifer; Cuison, Severino; Sung, Janette; Passmore, David; Chong, Colin; Greenbaum, Meghan; Kwok, Eilene; Jiang, Jerry; Pan, Chin; Rao-Naik, Chetana; Rangan, Vangipuram; Kempe, Tom; Tatum, Andrea; Deshpande, Shrikant; Cardarelli, Pina; Vite, Gregory; Gangwar, Sanjeev 分享 收藏
Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies Kotapati, Srikanth; Passmore, David; Yamazoe, Sayumi; Sanku, Rajesh Kishore Kumar; Cong, Qiang; Poudel, Yam B.; Chowdari, Naidu S.; Gangwar, Sanjeev; Rao, Chetana; Rangan, Vangipuram S.; Cardarelli, Pina M.; Deshpande, Shrikant; Strop, Pavel; Dollinger, Gavin; Rajpal, Arvind 分享 收藏
Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment Wu, Adela; Maxwell, Russell; Xia, Yuanxuan; Cardarelli, Pina; Oyasu, Miho; Belcaid, Zineb; Kim, Eileen; Hung, Alice; Luksik, Andrew S.; Garzon-Muvdi, Tomas; Jackson, Christopher M.; Mathios, Dimitrios; Theodros, Debebe; Cogswell, John; Brem, Henry; Pardoll, Drew M.; Lim, Michael 分享 收藏
The combination of CXCR4 and checkpoint receptor inhibition improves survival in an orthotopic murine glioma model Wu, Adela; Cardarelli, Pina; Oyasu, Miho; Menezes, Daniel; Ponath, Paul; Cogswell, John; Maxwell, Russell; Luksik, Andrew; Hung, Alice; Kim, Eileen; Belcaid, Zineb; Brem, Henry; Pardoll, Drew; Lim, Michael 分享 收藏
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CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation Roccaro, Aldo M.; Mishima, Yuji; Sacco, Antonio; Moschetta, Michele; Tai, Yu-Tzu; Shi, Jiantao; Zhang, Yong; Reagan, Michaela R.; Huynh, Daisy; Kawano, Yawara; Sahin, Ilyas; Chiarini, Marco; Manier, Salomon; Cea, Michele; Aljawai, Yosra; Glavey, Siobhan; Morgan, Elizabeth; Pan, Chin; Michor, Franziska; Cardarelli, Pina; Kuhne, Michelle; Ghobrial, Irene M. 分享 收藏
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Enzymology of the mechanism of action for MDX-1203 antibody drug conjugate Derwin, Daniel W.; Passmore, David; Zhang, Qian; Sufi, Bilal; Pan, Chin; Rao, Chetana; Huber, Mary; Gangwar, Sanjeev; Cardarelli, Pina; Deshpande, Shrikant; Rangan, Vangipuram 分享 收藏
Glycan optimization of a human monoclonal antibody in the aquatic plant Lemna minor Cox, Kevin M.; Sterling, Jason D.; Regan, Jeffrey T.; Gasdaska, John R.; Frantz, Karen K.; Peele, Charles G.; Black, Amelia; Passmore, David; Moldovan-Loomis, Cristina; Srinivasan, Mohan; Cuison, Severino; Cardarelli, Pina M.; Dickey, Lynn F. 分享 收藏
Production of human monoclonal antibody in eggs of chimeric chickens Zhu, L; van de Lavoir, MC; Albanese, J; Beenhouwer, DO; Cardarelli, PM; Cuison, S; Deng, DF; Deshpande, S; Diamond, JH; Green, L; Halk, EL; Heyer, BS; Kay, RM; Kerchner, A; Leighton, PA; Mather, CM; Morrison, SL; Nikolov, ZL; Passmore, DB; Pradas-Monne, A; Preston, BT; Rangan, VS; Shi, MX; Srinivasan, M; White, SG; Winters-Digiacinto, P; Wong, S; Zhou, W; Etches, RJ 分享 收藏
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