Yoh Takuwa - Publications, H-index & Citations

Yoh Takuwa

roche holding

63H指数

295论文数

1.4W被引数

收录论文 74

发表时间

Discoidin domain receptor 2 signaling through PIK3C2α in fibroblasts promotes lung fibrosis

JOURNAL OF PATHOLOGY

IF5.2

2024-02-09

OAAI

Ling, Song; Kwak, Doyun; Takuwa, Yoh; Ge, Chunxi; Franceschi, Renny; Kim, Kevin K.

Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes

JOURNAL OF LIPID RESEARCH

IF4.1

2023-11-01

OAAI

Morishige, Jun-ichi; Yoshioka, Kazuaki; Nakata, Hiroki; Ishimaru, Kazuhiro; Nagata, Naoto; Tanaka, Tamotsu; Takuwa, Yoh; Ando, Hitoshi

Ras activity late in G(1) phase required for p27(kip1) downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

176

OAAI

Takuwa, N; Takuwa, Y

Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

314

OAAI

Okamoto, H; Takuwa, N; Yokomizo, T; Sugimoto, N; Sakurada, S; Shigematsu, H; Takuwa, Y

Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

255

OAAI

Sugimoto, N; Takuwa, N; Okamoto, H; Sakurada, S; Takuwa, Y

Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells

SCIENTIFIC REPORTS

IF3.9

2021-03-04

OAAI

Shimizu, Shota; Yoshioka, Kazuaki; Aki, Sho; Takuwa, Yoh

TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2020-03-01

OAAI

Aki, Sho; Yoshioka, Kazuaki; Takuwa, Noriko; Takuwa, Yoh

Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation

SCIENTIFIC REPORTS

IF3.9

2019-12-04

OAAI

Ishimaru, Kazuhiro; Yoshioka, Kazuaki; Kano, Kuniyuki; Kurano, Makoto; Saigusa, Daisuke; Aoki, Junken; Yatomi, Yutaka; Takuwa, Noriko; Okamoto, Yasuo; Proia, Richard L.; Takuwa, Yoh

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4 溶血磷脂酸诱导的YAP/TAZ激活通过抑制Notch配体Dll4促进发育中的血管生成

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-09-09

OAAI

Yasuda, Daisuke; Kobayashi, Daiki; Akahoshi, Noriyuki; Ohto-Nakanishi, Takayo; Yoshioka, Kazuaki; Takuwa, Yoh; Mizuno, Seiya; Takahashi, Satoru; Ishii, Satoshi

Class II PI3Ks α and β Are Required for Rho-Dependent Uterine Smooth Muscle Contraction and Parturition in Mice

ENDOCRINOLOGY

IF3.3

2018-11-21

OAAI

Sarker, Md Azadul Kabir; Aki, Sho; Yoshioka, Kazuaki; Kuno, Kouji; Okamoto, Yasuo; Ishimaru, Kazuhiro; Takuwa, Noriko; Takuwa, Yoh

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease

NATURE COMMUNICATIONS

IF15.7

2018-04-16

OAAI

Lee, Ju Youn; Han, Seung Hoon; Park, Min Hee; Baek, Bosung; Song, Im-Sook; Choi, Min-Koo; Takuwa, Yoh; Ryu, Hoon; Kim, Seung Hyun; He, Xingxuan; Schuchman, Edward H.; Bae, Jae-Sung; Jin, Hee Kyung

Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo

SCIENTIFIC REPORTS

IF3.9

2017-12-05

OAAI

Funaki, Masaya; Kitabayashi, Juria; Shimakami, Tetsuro; Nagata, Naoto; Sakai, Yuriko; Takegoshi, Kai; Okada, Hikari; Murai, Kazuhisa; Shirasaki, Takayoshi; Oyama, Takeru; Yamashita, Taro; Ota, Tsuguhito; Takuwa, Yoh; Honda, Masao; Kaneko, Shuichi

Phosphatidylinositol 3-Kinase Class II α-Isoform PI3K-C2α Is Required for Transforming Growth Factor β-induced Smad Signaling in Endothelial Cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-03-01

OAAI

Aki, Sho; Yoshioka, Kazuaki; Okamoto, Yasuo; Takuwa, Noriko; Takuwa, Yoh

Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

DIABETOLOGIA

IF10.2

2014-07-03

OAAI

Ishikura, Kazuhide; Misu, Hirofumi; Kumazaki, Masafumi; Takayama, Hiroaki; Matsuzawa-Nagata, Naoto; Tajima, Natsumi; Chikamoto, Keita; Lan, Fei; Ando, Hitoshi; Ota, Tsuguhito; Sakurai, Masaru; Takeshita, Yumie; Kato, Kenichiro; Fujimura, Akio; Miyamoto, Ken-ichi; Saito, Yoshiro; Kameo, Satomi; Okamoto, Yasuo; Takuwa, Yoh; Takahashi, Kazuhiko; Kidoya, Hiroyasu; Takakura, Nobuyuki; Kaneko, Shuichi; Takamura, Toshinari

Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2013-11-01

OAAI

Cui, Hong; Okamoto, Yasuo; Yoshioka, Kazuaki; Du, Wa; Takuwa, Noriko; Zhang, Wei; Asano, Masahide; Shibamoto, Toshishige; Takuwa, Yoh

Essential Role of Class II Phosphatidylinositol-3-kinase-C2α in Sphingosine 1-Phosphate Receptor-1-mediated Signaling and Migration in Endothelial Cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-01-01

OAAI

Biswas, Kuntal; Yoshioka, Kazuaki; Asanuma, Ken; Okamoto, Yasuo; Takuwa, Noriko; Sasaki, Takehiko; Takuwa, Yoh

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2013-01-01

OAAI

Takuwa, Yoh; Ikeda, Hitoshi; Okamoto, Yasuo; Takuwa, Noriko; Yoshioka, Kazuaki

Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet-Fed Mice

DIABETES

IF7.5

2012-11-15

129

OAAI

Bruce, Clinton R.; Risis, Steve; Babb, Joanne R.; Yang, Christine; Kowalski, Greg M.; Selathurai, Ahrathy; Lee-Young, Robert S.; Weir, Jacquelyn M.; Yoshioka, Kazuaki; Takuwa, Yoh; Meikle, Peter J.; Pitson, Stuart M.; Febbraio, Mark A.

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents

HEPATOLOGY

IF15.8

2012-10-01

OAAI

Kageyama, Yuko; Ikeda, Hitoshi; Watanabe, Naoko; Nagamine, Masakazu; Kusumoto, Yoshika; Yashiro, Mitsuru; Satoh, Yumiko; Shimosawa, Tatsuo; Shinozaki, Koji; Tomiya, Tomoaki; Inoue, Yukiko; Nishikawa, Takako; Ohtomo, Natsuko; Tanoue, Yasushi; Yokota, Hiromitsu; Koyama, Takatoshi; Ishimaru, Kazuhiro; Okamoto, Yasuo; Takuwa, Yoh; Koike, Kazuhiko; Yatomi, Yutaka

Sphingosine-1-phosphate signaling in physiology and diseases

BIOFACTORS

IF5

2012-06-07

114

OAAI

Takuwa, Yoh; Okamoto, Yasuo; Yoshioka, Kazuaki; Takuwa, Noriko

研究方向