未登录 Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury Larraufie, Marie-Helene; Gao, Xiaolin; Xia, Xiaobo; Devine, Patrick J.; Kallen, Joerg; Liu, Dong; Michaud, Gregory; Harsch, Andreas; Savage, Nik; Ding, Jian; Tan, Kian; Mihalic, Manuel; Roggo, Silvio; Canham, Stephen M.; Bushell, Simon M.; Krastel, Philipp; Gao, Jinhai; Izaac, Aude; Altinoglu, Erhan; Lustenberger, Philipp; Salcius, Michael; Harbinski, Fred; Williams, Eric T.; Zeng, Liling; Loureiro, Joseph; Cong, Feng; Fryer, Christy J.; Klickstein, Lloyd; Tallarico, John A.; Jain, Rishi K.; Rothman, Deborah M.; Wang, Shaowen 分享 收藏
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Systematic Chemogenetic Library Assembly Canham, Stephen M.; Wang, Yuan; Cornett, Allen; Auld, Douglas S.; Baeschlin, Daniel K.; Patoor, Maude; Skaanderup, Philip R.; Honda, Ayako; Llamas, Luis; Wendel, Greg; Mapa, Felipa A.; Aspesi, Peter, Jr.; Labbe-Giguere, Nancy; Gamber, Gabriel G.; Palacios, Daniel S.; Schuffenhauer, Ansgar; Deng, Zhan; Nigsch, Florian; Frederiksen, Mathias; Bushell, Simon M.; Rothman, Deborah; Jain, Rishi K.; Hemmerle, Horst; Briner, Karin; Porter, Jeffery A.; Tallarico, John A.; Jenkins, Jeremy L. 分享 收藏
Discovery of a ZIP7 inhibitor from a Notch pathway screen Nolin, Erin; Gans, Sara; Llamas, Luis; Bandyopadhyay, Somnath; Brittain, Scott M.; Bernasconi-Elias, Paula; Carter, Kyle P.; Loureiro, Joseph J.; Thomas, Jason R.; Schirle, Markus; Yang, Yi; Guo, Ning; Roma, Guglielmo; Schuierer, Sven; Beibel, Martin; Lindeman, Alicia; Sigoillot, Frederic; Chen, Amy; Xie, Kevin X.; Ho, Samuel; Reece-Hoyes, John; Weihofen, Wilhelm A.; Tyskiewicz, Kayla; Hoepfner, Dominic; McDonald, Richard, I; Guthrie, Nicolette; Dogra, Abhishek; Guo, Haibing; Shao, Jian; Ding, Jian; Canham, Stephen M.; Boynton, Geoff; George, Elizabeth L.; Karig, Zhao B.; Antcza, Christophe; Porter, Jeffery A.; Wallace, Owen; Tallarico, John A.; Palmer, Amy E.; Jenkins, Jeremy L.; Jain, Rishi K.; Bushell, Simon M.; Fryer, Christyj 分享 收藏
Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection LaMarche, Matthew J.; Leeds, Jennifer A.; Amaral, Adam; Brewer, Jason T.; Bushell, Simon M.; Deng, Gejing; Dewhurst, Janetta M.; Ding, Jian; Dzink-Fox, JoAnne; Gamber, Gabriel; Jain, Akash; Lee, Kwangho; Lee, Lac; Lister, Troy; McKenney, David; Mullin, Steve; Osborne, Colin; Palestrant, Deborah; Patane, Michael A.; Rann, Elin M.; Sachdeva, Meena; Shao, Jian; Tiamfook, Stacey; Trzasko, Anna; Whitehead, Lewis; Yifru, Aregahegn; Yu, Donghui; Yan, Wanlin; Zhu, Qingming 分享 收藏
In Vitro and In Vivo Activities of Novel, Semisynthetic Thiopeptide Inhibitors of Bacterial Elongation Factor Tu Leeds, J. A.; LaMarche, M. J.; Brewer, J. T.; Bushell, S. M.; Deng, G.; Dewhurst, J. M.; Dzink-Fox, J.; Gangl, E.; Jain, A.; Lee, L.; Lilly, M.; Manni, K.; Mullin, S.; Neckermann, G.; Osborne, C.; Palestrant, D.; Patane, M. A.; Raimondi, A.; Ranjitkar, S.; Rann, E. M.; Sachdeva, M.; Shao, J.; Tiamfook, S.; Whitehead, L.; Yu, D. 分享 收藏
Antibacterial Optimization of 4-Aminothiazolyl Analogues of the Natural Product GE2270 A: Identification of the Cycloalkylcarboxylic Acids LaMarche, Matthew J.; Leeds, Jennifer A.; Amaral, Kerri; Brewer, Jason T.; Bushell, Simon M.; Dewhurst, Janetta M.; Dzink-Fox, JoAnne; Gangl, Eric; Goldovitz, Julie; Jain, Akash; Mullin, Steve; Neckermann, Georg; Osborne, Colin; Palestrant, Deborah; Patane, Michael A.; Rann, Elin M.; Sachdeva, Meena; Shao, Jian; Tiamfbok, Stacey; Whitehead, Lewis; Yu, Donghui 分享 收藏
Inhibition of Dengue Virus through Suppression of Host Pyrimidine Biosynthesis Wang, Qing-Yin; Bushell, Simon; Qing, Min; Xu, Hao Ying; Bonavia, Aurelio; Nunes, Sandra; Zhou, Jing; Poh, Mee Kian; de Sessions, Paola Florez; Niyomrattanakit, Pornwaratt; Dong, Hongping; Hoffmaster, Keith; Goh, Anne; Nilar, Shahul; Schul, Wouter; Jones, Susan; Kramer, Laura; Compton, Teresa; Shi, Pei-Yong 分享 收藏
Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV) Bonavia, Aurelio; Franti, Michael; Keaney, Erin Pusateri; Kuhen, Kelli; Seepersaud, Mohindra; Radetich, Branko; Shao, Jian; Honda, Ayako; Dewhurst, Janetta; Balabanis, Kara; Monroe, James; Wolff, Karen; Osborne, Colin; Lanieri, Leanne; Hoffmaster, Keith; Amin, Jakal; Markovits, Judit; Broome, Michelle; Skuba, Elizabeth; Cornella-Taracido, Ivan; Joberty, Gerard; Bouwmeester, Tewis; Hamann, Lawrence; Tallarico, John A.; Tommasi, Ruben; Compton, Teresa; Bushell, Simon M. 分享 收藏
Progress toward a rationally designed, chemically powered rotary molecular motor Kelly, T. Ross; Cai, Xiaolu; Damkaci, Fehmi; Panicker, Sreeletha B.; Tu, Bin; Bushell, Simon M.; Cornella, Ivan; Piggott, Matthew J.; Salives, Richard; Cavero, Marta; Zhao, Yajun; Jasmin, Serge 分享 收藏
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Structure-activity relationships for 1-alkyl-3-(l-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors:: steric and electronic effects of naphthoyl substituents.: New highly selective CB2 receptor agonists 大麻素CB1和CB2受体上1-烷基-3-(1-萘甲酰基) 吲哚的构效关系: 萘甲酰基取代基的空间和电子效应: 新型高选择性CB2受体激动剂 Huffman, JW; Zengin, G; Wu, MJ; Lu, JZ; Hynd, G; Bushell, K; Thompson, ALS; Bushell, S; Tartal, C; Hurst, DP; Reggio, PH; Selley, DE; Cassidy, MP; Wiley, JL; Martin, BR 分享 收藏
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