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Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease Virgincar, Rohan S.; Wong, Aaron K.; Barck, Kai H.; Webster, Joshua D.; Hung, Jeffrey; Caplazi, Patrick; Choy, Man Kin; Forrest, William F.; Bell, Laura C.; de Crespigny, Alex J.; Dunlap, Debra; Jones, Charles; Kim, Dong Eun; Weimer, Robby M.; Shaw, Andrey S.; Brightbill, Hans D.; Xie, Luke 分享 收藏
Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema Stockwell, Amy D.; Chang, Michael C. C.; Mahajan, Anubha; Forrest, William; Anegondi, Neha; Pendergrass, Rion K.; Selvaraj, Suresh; Reeder, Jens; Wei, Eric; Iglesias, V. A.; Creps, Natalie M.; Macri, Laura; Neeranjan, Andrea N.; van der Brug, Marcel P.; Scales, Suzie J.; McCarthy, Mark I.; Yaspan, Brian L. 分享 收藏
Quantifying KRAS G12C Covalent Drug Inhibitor Activity in Mouse Tumors Using Mass Spectrometry Tran, John C.; Hunsaker, Thomas; Bell, Christina; Ma, Taylur P.; Chan, Emily; Larrocha, Pablo Saenz-Lopez; Homyk, Kelsey; Liu, Liling; La, Hank; Mao, Jialin; de la Cruz, Cecile C.; Yu, Kebing; Beresini, Maureen; Forrest, William F.; Xiao, Yang; Jang, Anne; Samus, Natalia; Stesco, Nicholas Dupuis; Mentinova, Marija; Parent, Stephane; Pottiez, Gwenael; Schirm, Michael; Purkey, Hans E.; Liu, Yichin; Merchant, Mark 分享 收藏
A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk Chang, Diana; Hunkapiller, Julie; Bhangale, Tushar; Reeder, Jens; Mukhyala, Kiran; Tom, Jennifer; Cowgill, Amy; Vogel, Jan; Forrest, William F.; Khan, Zia; Stockwell, Amy; McCarthy, Mark, I; Staton, Tracy L.; Olsson, Julie; Holweg, Cecile T. J.; Cheung, Dorothy S.; Chen, Hubert; Brauer, Matthew J.; Graham, Robert R.; Behrens, Timothy; Wilson, Mark S.; Arron, Joseph R.; Choy, David F.; Yaspan, Brian L. 分享 收藏
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy 突变体PI3Kα 的RTK依赖性诱导降解驱动GDC-0077 (Inavolisib) 功效 Song, Kyung W.; Edgar, Kyle A.; Hanan, Emily J.; Hafner, Marc; Oeh, Jason; Merchant, Mark; Sampath, Deepak; Nannini, Michelle A.; Hong, Rebecca; Phu, Lilian; Forrest, William F.; Stawiski, Eric; Schmidt, Stephen; Endres, Nicholas; Guan, Jane; Wallin, Jeffrey J.; Cheong, Jonathan; Plise, Emile G.; Phillips, Gail D. Lewis; Salphati, Laurent; Heffron, Timothy P.; Olivero, Alan G.; Malek, Shiva; Staben, Steven T.; Kirkpatrick, Donald S.; Dey, Anwesha; Friedman, Lori S. 分享 收藏
Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity Weber, Martin; Min, Sang-Won; Truong, Tom; Hung, Jeffrey; Dale, Stephanie; Reichelt, Mike; Ubhayakar, Savita; Cain-Hom, Carol; Baca, Miriam; Jiang, Zhiyu; Li, Qingling; Brendza, Robert; Lin, Han; Kung, Chung; Forrest, William F.; Quiason-Huynh, Cristine; Sandoval, Wendy; Chen, Buyun; Deng, Yuzhong; Easton, Amy; Foreman, Oded; Sene, Abdoulaye; Bingol, Baris 分享 收藏
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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration 种系遗传多态性影响肿瘤基因表达和免疫细胞浸润 Lim, Yoong Wearn; Chen-Harris, Haiyin; Mayba, Oleg; Lianoglou, Steve; Wuster, Arthur; Bhangale, Tushar; Khan, Zia; Mariathasan, Sanjeev; Daemen, Anneleen; Reeder, Jens; Haverty, Peter M.; Forrest, William F.; Brauer, Matthew; Mellman, Ira; Albert, Matthew L. 分享 收藏
Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study Dressen, Amy; Abbas, Alexander R.; Cabanski, Christopher; Reeder, Janina; Ramalingam, Thirumalai R.; Neighbors, Margaret; Bhangale, Tushar R.; Brauer, Matthew J.; Hunkapiller, Julie; Reeder, Jens; Mukhyala, Kiran; Cuenco, Karen; Tom, Jennifer; Cowgill, Amy; Vogel, Jan; Forrest, William F.; Collard, Harold R.; Wolters, Paul J.; Kropski, Jonathan A.; Lancaster, Lisa H.; Blackwell, Timothy S.; Arron, Joseph R.; Yaspan, Brian L. 分享 收藏
Development and mechanistic characterization of USP7 deubiquitinase inhibitors Wertz, Ingrid; Kategaya, Lorna; Di Lello, Paola; Rouge, Lionel; Pastor, Richard; Clark, Kevin R.; Drummond, Jason; Kleinheinz, Tracy; Lin, Eva; Upton, John-Paul; Prakash, Sumit; Heideker, Johanna; McCleland, Mark; Ritorto, Maria Stella; Alessi, Dario R.; Trost, Matthias; Bainbridge, Travis W.; Kwok, Michael C.; Ma, Taylur P.; Stiffler, Zachary; Brasher, Bradley; Tang, Yinyan; Jaishanker, Priya; Hearn, Brian; Renslo, Adam R.; Arkin, Michelle R.; Cohen, Frederick; Yu, Kebing; Peale, Frank; Gnad, Florian; Chang, Matthew T.; Klijn, Christiaan; Blackwood, Elizabeth; Martin, Scott E.; Forrest, William F.; Ernst, James A.; Ndubaku, Chudi; Wang, Xiaojing; Beresini, Maureen H.; Tsui, Vickie; Schwerdtfeger, Carsten; Blake, Robert A.; Murray, Jeremy; Maurer, Till 分享 收藏
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Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes Hewings, David S.; Heideker, Johanna; Ma, Taylur P.; AhYoung, Andrew P.; El Oualid, Farid; Amore, Alessia; Costakes, Gregory T.; Kirchhofer, Daniel; Brasher, Bradley; Pillow, Thomas; Popovych, Nataliya; Maurer, Till; Schwerdtfeger, Carsten; Forrest, William F.; Yu, Kebing; Flygare, John; Bogyo, Matthew; Wertz, Ingrid E. 分享 收藏
Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms Haug-Baltzell, Asher; Bhangale, Tushar R.; Chang, Diana; Dressen, Amy; Yaspan, Brian L.; Ortmann, Ward; Brauer, Matthew J.; Hunkapiller, Julie; Reeder, Jens; Mukhyala, Kiran; Cuenco, Karen T.; Tom, Jennifer A.; Cowgill, Amy; Vogel, Jan; Forrest, William F.; Behrens, Timothy W.; Graham, Robert R.; Wuster, Arthur 分享 收藏
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BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats Weber, Martin; Wu, Tiffany; Meilandt, William J.; Dominguez, Sara L.; Solanoy, Hilda O.; Maloney, Janice A.; Ngu, Hai; Baca, Miriam; Kung, Chung; Lima, Lisa; Earr, Timothy K.; Fleck, Daniel; Shields, Shannon D.; Forrest, William F.; Foreman, Oded; Warming, Soren; Watts, Ryan J.; Scearce-Levie, Kimberly 分享 收藏
Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death Anania, Veronica G.; Yu, Kebing; Gnad, Florian; Pferdehirt, Rebecca R.; Li, Han; Ma, Taylur P.; Jeon, Diana; Fortelny, Nikolaus; Forrest, William; Ashkenazi, Avi; Overall, Christopher M.; Lill, Jennie R. 分享 收藏
Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents Ong, Christy C.; Gierke, Sarah; Pitt, Cameron; Sagolla, Meredith; Cheng, Christine K.; Zhou, Wei; Jubb, Adrian M.; Strickland, Laura; Schmidt, Maike; Duron, Sergio G.; Campbell, David A.; Zheng, Wei; Dehdashti, Seameen; Shen, Min; Yang, Nora; Behnke, Mark L.; Huang, Wenwei; Mckew, John C.; Chernoff, Jonathan; Forrest, William F.; Haverty, Peter M.; Chin, Suet-Feung; Rakha, Emad A.; Green, Andrew R.; Ellis, Ian O.; Caldas, Carlos; O'Brien, Thomas; Friedman, Lori S.; Koeppen, Hartmut; Rudolph, Joachim; Hoeflich, Klaus P. 分享 收藏
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