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Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency Gonzalez, Bryan J.; Zhao, Haoquan; Niu, Jacqueline; Williams, Damian J.; Lee, Jaeyop; Goulbourne, Chris N.; Xing, Yuan; Wang, Yong; Oberholzer, Jose; Blumenkrantz, Maria H.; Chen, Xiaojuan; LeDuc, Charles A.; Chung, Wendy K.; Colecraft, Henry M.; Gromada, Jesper; Shen, Yufeng; Goland, Robin S.; Leibel, Rudolph L.; Egli, Dieter 分享 收藏
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Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance Adam, Rene C.; Mintah, Ivory J.; Alexa-Braun, Corey A.; Shihanian, Lisa M.; Lee, Joseph S.; Banerjee, Poulabi; Hamon, Sara C.; Kim, Hye In; Cohen, Jonathan C.; Hobbs, Helen H.; Van Hout, Cristopher; Gromada, Jesper; Murphy, Andrew J.; Yancopoulos, George D.; Sleeman, Mark W.; Gusarova, Viktoria 分享 收藏
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells Gray, Sarah M.; Xin, Yurong; Ross, Elizabeth C.; Chazotte, Bryanna M.; Capozzi, Megan E.; El, Kimberley; Svendsen, Berit; Ravn, Peter; Sloop, Kyle W.; Tong, Jenny; Gromada, Jesper; Campbell, Jonathan E.; D'Alessio, David A. 分享 收藏
Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice[S] Pouwer, Marianne G.; Pieterman, Elsbet J.; Worms, Nicole; Keijzer, Nanda; Jukema, J. Wouter; Gromada, Jesper; Gusarova, Viktoria; Princen, Hans M. G. 分享 收藏
Clinical and Molecular Prevalence of Lipodystrophy in an Unascertained Large Clinical Care Cohort Gonzaga-Jauregui, Claudia; Ge, Wenzhen; Staples, Jeffrey; Van Hout, Cristopher; Yadav, Ashish; Colonie, Ryan; Leader, Joseph B.; Kirchner, H. Lester; Murray, Michael F.; Reid, Jeffrey G.; Carey, David J.; Overton, John D.; Shuldiner, Alan R.; Gottesman, Omri; Gao, Steve; Gromada, Jesper; Baras, Aris; Altarejos, Judith 分享 收藏
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion Dwivedi, Om Prakash; Lehtovirta, Mikko; Hastoy, Benoit; Chandra, Vikash; Krentz, Nicole A. J.; Kleiner, Sandra; Jain, Deepak; Richard, Ann-Marie; Abaitua, Fernando; Beer, Nicola L.; Grotz, Antje; Prasad, Rashmi B.; Hansson, Ola; Ahlqvist, Emma; Krus, Ulrika; Artner, Isabella; Suorantal, Anu; Gomez, Daniel; Baras, Aris; Champon, Benoite; Payne, Anthony J.; Moralli, Daniela; Thomsen, Soren K.; Kramer, Philipp; Spiliotis, Ioannis; Ramracheya, Reshma; Chabosseau, Pauline; Theodoulou, Andria; Cheung, Rebecca; van de Bunt, Martijn; Flannick, Jason; Trombetta, Maddalena; Bonora, Enzo; Wolheim, Claes B.; Sarelin, Leena; Bonadonna, Riccardo C.; Rorsman, Patrik; Davies, Benjamin; Brosnan, Julia; McCarthy, Mark, I; Otonkoski, Timo; Lagerstedt, Jens O.; Rutter, Guy A.; Gromada, Jesper; Gloyn, Anna L.; Tuomi, Tiinamaija; Groop, Leif 分享 收藏
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Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells (vol 46, pg 120, 2018) Rajasekaran, Subu Surendran; Kim, Jaeyoon; Gaboardi, Gian-Carlo; Gromada, Jesper; Shears, Stephen B.; dos Santos, Karen Tiago; Nolasco, Eduardo Lima; Ferreira, Sabrina de Souza; Illies, Christopher; Kohler, Martin; Gu, Chunfang; Ryu, Sung Ho; Martins, Joilson O.; Dare, Elisabetta; Barker, Christopher J.; Berggren, Per-Olof 分享 收藏
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Gene Signature of the Human Pancreatic ε Cell Gutierrez, Giselle Dominguez; Kim, Jinrang; Lee, Ann-Hwee; Tong, Jenny; Niu, JingJing; Gray, Sarah M.; Wei, Yi; Ding, Yueming; Ni, Min; Adler, Christina; Murphy, Andrew J.; Gromada, Jesper; Xin, Yurong 分享 收藏
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Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity Kleiner, Sandra; Gomez, Daniel; Megra, Bezawit; Na, Erqian; Bhavsar, Ramandeep; Cavino, Katie; Xin, Yurong; Rojas, Jose; Dominguez-Gutierrez, Giselle; Zambrowicz, Brian; Carrat, Gaelle; Chabosseau, Pauline; Hu, Ming; Murphy, Andrew J.; Yancopoulos, George D.; Rutter, Guy A.; Gromada, Jesper 分享 收藏
Gene Signature of Proliferating Human Pancreatic α Cells 增殖的人胰腺 α 细胞的基因签名 Gutierrez, Giselle Dominguez; Xin, Yurong; Okamoto, Haruka; Kim, Jinrang; Lee, Ann-Hwee; Ni, Min; Adler, Christina; Yancopoulos, George D.; Murphy, Andrew J.; Gromada, Jesper 分享 收藏
Pseudotime Ordering of Single Human -Cells Reveals States of Insulin Production and Unfolded Protein Response Xin, Yurong; Gutierrez, Giselle Dominguez; Okamoto, Haruka; Kim, Jinrang; Lee, Ann-Hwee; Adler, Christina; Ni, Min; Yancopoulos, George D.; Murphy, Andrew J.; Gromada, Jesper 分享 收藏
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes ANGPTL4基因失活改善血糖稳态并与糖尿病风险降低相关 Gusarova, Viktoria; O'Dushlaine, Colm; Teslovich, Tanya M.; Benotti, Peter N.; Mirshahi, Tooraj; Gottesman, Omri; Van Hout, Cristopher V.; Murray, Michael F.; Mahajan, Anubha; Nielsen, Jonas B.; Fritsche, Lars; Wulff, Anders Berg; Gudbjartsson, Daniel F.; Sjogren, Marketa; Emdin, Connor A.; Scott, Robert A.; Lee, Wen-Jane; Small, Aeron; Kwee, Lydia C.; Dwivedi, Om Prakash; Prasad, Rashmi B.; Bruse, Shannon; Lopez, Alexander E.; Penn, John; Marcketta, Anthony; Leader, Joseph B.; Still, Christopher D.; Kirchner, H. Lester; Mirshahi, Uyenlinh L.; Wardeh, Amr H.; Hartle, Cassandra M.; Habegger, Lukas; Fetterolf, Samantha N.; Tusie-Luna, Teresa; Morris, Andrew P.; Holm, Hilma; Steinthorsdottir, Valgerdur; Sulem, Patrick; Thorsteinsdottir, Unnur; Rotter, Jerome I.; Chuang, Lee-Ming; Damrauer, Scott; Birtwell, David; Brummett, Chad M.; Khera, Amit V.; Natarajan, Pradeep; Orho-Melander, Marju; Flannick, Jason; Lotta, Luca A.; Willer, Cristen J.; Holmen, Oddgeir L.; Ritchie, Marylyn D.; Ledbetter, David H.; Murphy, Andrew J.; Borecki, Ingrid B.; Reid, Jeffrey G.; Overton, John D.; Hansson, Ola; Groop, Leif; Shah, Svati H.; Kraus, William E.; Rader, Daniel J.; Chen, Yii-Der I.; Hveem, Kristian; Wareham, Nicholas J.; Kathiresan, Sekar; Melander, Olle; Stefansson, Kari; Nordestgaard, Borge G.; Tybjaerg-Hansen, Anne; Abecasis, Goncalo R.; Altshuler, David; Florez, Jose C.; Boehnke, Michael; McCarthy, Mark I.; Yancopoulos, George D.; Carey, David J.; Shuldiner, Alan R.; Baras, Aris; Dewey, Frederick E.; Gromada, Jesper 分享 收藏
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