Andrew D. Rowan - Publications, H-index & Citations

Andrew D. Rowan

newcastle university - uk

44H指数

101论文数

5.2K被引数

收录论文 31

发表时间

Matrix metalloproteinase-13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha-1 antitrypsin: Implications for osteoarthritis

FEBS JOURNAL

IF4.2

2021-07-30

OAAI

Wilkinson, David J.; Falconer, Adrian M. D.; Wright, Helen L.; Lin, Hua; Yamamoto, Kazuhiro; Cheung, Kathleen; Charlton, Sarah H.; Arques, Maria del Carmen; Janciauskiene, Sabina; Refaie, Ramsay; Rankin, Kenneth S.; Young, David A.; Rowan, Andrew D.

Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-06-01

OAAI

Falconer, Adrian M. D.; Chan, Chun Ming; Gray, Joseph; Nagashima, Izuru; Holland, Robert A.; Shimizu, Hiroki; Pickford, Andrew R.; Rowan, Andrew D.; Wilkinson, David J.

Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2018-03-30

OAAI

Wilkinson, David J.; Arques, Maria del Carmen; Huesa, Carmen; Rowan, Andrew D.

The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover

SCIENTIFIC REPORTS

IF3.9

2017-12-01

OAAI

Wilkinson, David J.; Desilets, Antoine; Lin, Hua; Charlton, Sarah; Arques, Maria del Carmen; Falconer, Adrian; Bullock, Craig; Hsu, Yu-Chen; Birchall, Kristian; Hawkins, Alastair; Thompson, Paul; Ferrell, William R.; Lockhart, John; Plevin, Robin; Zhang, Yadan; Blain, Emma; Lin, Shu-Wha; Leduc, Richard; Milner, Jennifer M.; Rowan, Andrew D.

Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms

ARTHRITIS & RHEUMATOLOGY

IF10.9

2017-07-05

OAAI

Wilkinson, David J.; Habgood, Angela; Lamb, Heather K.; Thompson, Paul; Hawkins, Alastair R.; Desilets, Antoine; Leduc, Richard; Steinmetzer, Torsten; Hammami, Maya; Lee, Melody S.; Craik, Charles S.; Watson, Sharon; Lin, Hua; Milner, Jennifer M.; Rowan, Andrew D.

Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-02-01

OAAI

Chan, Chun Ming; Macdonald, Christopher D.; Litherland, Gary J.; Wilkinson, David J.; Skelton, Andrew; Europe-Finner, G. Nicholas; Rowan, Andrew D.

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2016-11-01

OAAI

Huesa, Carmen; Ortiz, Ana C.; Dunning, Lynette; McGavin, Laura; Bennett, Louise; McIntosh, Kathryn; Crilly, Anne; Kurowska-Stolarska, Mariola; Plevin, Robin; van't Hof, Rob J.; Rowan, Andrew D.; McInnes, Iain B.; Goodyear, Carl S.; Lockhart, John C.; Ferrell, William R.

Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2016-02-01

134

OAAI

Hui, Wang; Young, David A.; Rowan, Andrew D.; Xu, Xin; Cawston, Tim E.; Proctor, Carole J.

Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2015-08-01

OAAI

Radwan, Marta; Wilkinson, David J.; Hui, Wang; Destrument, Auriane P. M.; Charlton, Sarah H.; Barter, Matt J.; Gibson, Beth; Coulombe, Josee; Gray, Douglas A.; Rowan, Andrew D.; Young, David A.

Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis

ARTHRITIS & RHEUMATOLOGY

IF10.9

2014-07-28

PREAI

Litherland, Gary J.; Hui, Wang; Elias, Martina S.; Wilkinson, David J.; Watson, Sharon; Huesa, Carmen; Young, David A.; Rowan, Andrew D.

INVESTIGATING MOLECULAR MECHANISMS OF AGEING CARTILAGE USING COMPUTER SIMULATION MODELS

OSTEOARTHRITIS AND CARTILAGE

IF9

2014-04-01

PREAI

Hui, W.; Young, D. A.; Rowan, A. D.; Cawston, T. E.; Proctor, C. J.

A Computer Simulation Approach to Assessing Therapeutic Intervention Points for the Prevention of Cytokine-Induced Cartilage Breakdown

ARTHRITIS & RHEUMATOLOGY

IF10.9

2014-03-28

OAAI

Proctor, C. J.; Macdonald, C.; Milner, J. M.; Rowan, A. D.; Cawston, T. E.

Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

OSTEOARTHRITIS AND CARTILAGE

IF9

2012-09-01

OAAI

Xu, Y.; Barter, M. J.; Swan, D. C.; Rankin, K. S.; Rowan, A. D.; Santibanez-Koref, M.; Loughlin, J.; Young, D. A.

cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

FASEB JOURNAL

IF4.2

2012-04-13

PREAI

Bui, Catherine; Barter, Matt J.; Scott, Jenny L.; Xu, Yaobo; Galler, Martin; Reynard, Louise N.; Rowan, Andrew D.; Young, David A.

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2012-03-01

183

OAAI

Hui, Wang; Litherland, Gary J.; Elias, Martina S.; Kitson, Gareth I.; Cawston, Tim E.; Rowan, Andrew D.; Young, David A.

ANTIGEN-SPECIFIC B CELLS CAN ACQUIRE AND PRESENT THE RHEUMATOID ARTHRITIS CANDIDATE AUTOANTIGEN AGGRECAN FROM A NON-INTERNALISABLE SURFACE

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2011-03-01

OAAI

Ciechomska, Marzena; Wilson, Caroline; Rowan, Andrew; Robinson, John H.; Knight, Andrew M.

MATRIPTASE IS A NOVEL INITIATOR OF CARTILAGE MATRIX RESORPTION IN OSTEOARTHRITIS

OSTEOARTHRITIS AND CARTILAGE

IF9

2010-10-01

OAAI

Milner, J. M.; Patel, A.; Davidson, R. K.; Swingler, T. E.; Desilets, A.; Young, D. A.; Kelso, E. B.; Donell, S. T.; Cawston, T. E.; Clarke, I. M.; Ferrell, W. R.; Plevin, R.; Lockhart, J. C.; Leduc, R.; Rowan, A. D.

Overexpression of Oncostatin-M in lungs induces eotaxin-2 and eosinophil accumulation in C57BL/6 but not Balb/C mice in vivo

CYTOKINE

IF3.7

2010-10-01

PREAI

Richards, Carl D.; Kerr, Christine; Fritz, Dominik K.; Rowan, Andrew D.; Langdon, Carrie M.

Protein Kinase C Isoforms ζ and ι Mediate Collagenase Expression and Cartilage Destruction via STAT3-and ERK-dependent c-fos Induction

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-07-01

OAAI

Litherland, Gary J.; Elias, Martina S.; Hui, Wang; Macdonald, Christopher D.; Catterall, Jonathon B.; Barter, Matt J.; Farren, Matthew J.; Jefferson, Matthew; Rowan, Andrew D.

Hybrid density functional theory applied to magnetite: Crystal structure, charge order, and phonons

PHYSICAL REVIEW B

IF3.7

2009-05-05

OAAI

Rowan, Andrew D.; Patterson, Charles H.; Gasparov, L. V.

研究方向