未登录 High-resolution genome-wide mapping of chromosome-arm-scale truncations induced by CRISPR-Cas9 editing Lazar, Nathan H.; Celik, Safiye; Chen, Lu; Fay, Marta M.; Irish, Jonathan C.; Jensen, James; Tillinghast, Conor A.; Urbanik, John; Bone, William P.; Gibson, Christopher C.; Haque, Imran S. 分享 收藏
Phenomics-enabled discovery and optimization of small-molecule RBM39 degraders as an alternative to CDK12 targeting in high-grade serous ovarian cancer (HGSOC) Neumann, Chase; Shankaran, Harish; Nadella, Kiran; Biette, Kelly; Rowley, Shane; Gardner, Ethan; Swaidani, Shadi; Manda, Vamshi; Chen, Lu; Beshnova, Daria; Saeed, Ashraf; Bailey, Christopher; Paulsen, Janet; Rearden, Paul; Brooks, Carl; Bhandari, Ashish; Gibson, Chris; Schaevitz, Laura; Haque, Imran; Donnella, Hayley; Cuccarese, Michael; Evangelista, Marie 分享 收藏
A phenomics platform combining imaging and artificial intelligence for rapid validation and advancement of novel oncology targets Rudnick, Jenny; Nadella, Kiran; Neumann, Chase; Rowley, Shane; Gardner, Ethan; Swaidani, Shadi; Iberg, Aimee; Chen, Lu; Beshnova, Daria; Blucher, Aurora; Basso, Rebecca Sarto; Rajan, Malini; Fales, Kevin; Saeed, Ashraf; Bailey, Christopher; Judd, Weston; Egbert, Chrissy; Ellis, Joel; Ansede, John; Hadipour, Pouya; Jessing, Kevin; Paulsen, Janet; Rearden, Paul; Manda, Vamshi; Kasimsetty, Sashi; Kasimsetty, Sashi; Hancock, Michael; Shankaran, Harish; Ellis, Bryan; Iyer, Meenakshy; Brooks, Carl; Bhandari, Ashish; Gibson, Chris; Rappley, Irit; Schaevitz, Laura; Haque, Imran; Donnella, Hayley; Cuccarese, Michael; Evangelista, Marie 分享 收藏
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Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA 机器学习可通过对血浆无细胞DNA进行全基因组测序来检测早期结直肠癌 Wan, Nathan; Weinberg, David; Liu, Tzu-Yu; Niehaus, Katherine; Ariazi, Eric A.; Delubac, Daniel; Kannan, Ajay; White, Brandon; Bailey, Mitch; Bertin, Marvin; Boley, Nathan; Bowen, Derek; Cregg, James; Drake, Adam M.; Ennis, Riley; Fransen, Signe; Gafni, Erik; Hansen, Loren; Liu, Yaping; Otte, Gabriel L.; Pecson, Jennifer; Rice, Brandon; Sanderson, Gabriel E.; Sharma, Aarushi; St John, John; Tang, Catherina; Tzou, Abraham; Young, Leilani; Putcha, Girish; Haque, Imran S. 分享 收藏
Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissue-of-origin Liu, Yaping; Liu, Tzu-Yu; Weinberg, David; De La Torre, Chris J.; Tan, Catherine L.; Schmitt, Anthony D.; Selvaraj, Siddarth; Tran, Vy; Laurent, Louise C.; Bidard, Francois-Clement; Haque, Imran S. 分享 收藏
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Validation of an Expanded Carrier Screen that Optimizes Sensitivity via Full-Exon Sequencing and Panel-wide Copy Number Variant Identification Hogan, Gregory J.; Vysotskaia, Valentina S.; Beauchamp, Kyle A.; Seisenberger, Stefanie; Grauman, Peter V.; Haas, Kevin R.; Hong, Sun Hae; Jeon, Diana; Kash, Shera; Lai, Henry H.; Melroy, Laura M.; Theilmann, Mark R.; Chu, Clement S.; Iori, Kevin; Maguire, Jared R.; Evans, Eric A.; Haque, Imran S.; Mar-Heyming, Rebecca; Kang, Hyunseok P.; Muzzey, Dale 分享 收藏
Multi-analyte profiling reveals relationships among circulating biomarkers in colorectal cancer Delubac, Daniel; Ariazi, Eric; Berliner, Jonathan; Drake, Adam; Dulin, John; Ennis, Riley; Gafni, Erik; Niehaus, Kate; Otte, Gabriel; Pecson, Jennifer; Putcha, Girish; Schaninger, Corey; Sharma, Aarushi; Singer, Mike; Tzou, Abraham; Waters, Jill; Weinberg, David; White, Brandon; Haque, Imran S. 分享 收藏
Systematic design and comparison of expanded carrier screening panels Beauchamp, Kyle A.; Muzzey, Dale; Wong, Kenny K.; Hogan, Gregory J.; Karimi, Kambiz; Candille, Sophie I.; Mehta, Nikita; Mar-Heyming, Rebecca; Kaseniit, K. Eerik; Kang, H. Peter; Evans, Eric A.; Goldberg, James D.; Lazarin, Gabriel A.; Haque, Imran S. 分享 收藏
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