未登录 Cancer-Stem-Cell Phenotype-Guided Discovery of a Microbiota-Inspired Synthetic Compound Targeting NPM1 for Leukemia Algar, Sergio; Vazquez-Villa, Henar; Aguilar-Garrido, Pedro; Navarro-Aguadero, Miguel Angel; Velasco-Estevez, Maria; Sanchez-Merino, Anabel; Arribas-Alvarez, Ivan; Paradela, Alberto; Giner-Arroyo, Rafael L.; Tamargo-Azpilicueta, Joaquin; Diaz-Moreno, Irene; Martinez-Lopez, Joaquin; Gallardo, Miguel; Lopez-Rodriguez, Maria L.; Benhamu, Bellinda 分享 收藏
2-(Fluoromethoxy)-4′-(S-methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson's Disease 2-(氟甲氧基)-4 ′-(S-甲磺酰亚胺基)-1,1 ′-联苯 (UCM-1306)，人类多巴胺D1受体的口服生物可利用的正变构调节剂，用于帕金森氏病 Garcia-Carceles, Javier; Vazquez-Villa, Henar; Brea, Jose; Ladron de Guevara-Miranda, David; Cincilla, Giovanni; Sanchez-Martinez, Melchor; Sanchez-Merino, Anabel; Algar, Sergio; Teresa de los Frailes, Maria; Roberts, Richard S.; Ballesteros, Juan A.; Rodriguez de Fonseca, Fernando; Benhamu, Bellinda; Loza, Maria, I; Lopez-Rodriguez, Maria L. 分享 收藏
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Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice Khiar-Fernandez, Nora; Zian, Debora; Vazquez-Villa, Henar; Fernando Martinez, R.; Escobar-Pena, Andrea; Foronda-Sainz, Roman; Ray, Manisha; Puigdomenech-Poch, Maria; Cincilla, Giovanni; Sanchez-Martinez, Melchor; Kihara, Yasuyuki; Chun, Jerold; Lopez-Vales, Ruben; Lopez-Rodriguez, Maria L.; Ortega-Gutierrez, Silvia 分享 收藏
Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for Diabesity Decara, Juan M.; Vazquez-Villa, Henar; Brea, Jose; Alonso, Monica; Srivastava, Raj Kamal; Orio, Laura; Alen, Francisco; Suarez, Juan; Baixeras, Elena; Garcia-Carceles, Javier; Escobar-Pena, Andrea; Lutz, Beat; Rodriguez, Ramon; Codesido, Eva; Garcia-Ladona, F. Javier; Bennett, Teresa A.; Ballesteros, Juan A.; Cruces, Jacobo; Loza, Maria, I; Benhamu, Bellinda; Rodriguez de Fonseca, Fernando; Lopez-Rodriguez, Maria L. 分享 收藏
Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome Marcos-Ramiro, Beatriz; Gil-Ordonez, Ana; Marin-Ramos, Nagore, I; Ortega-Nogales, Francisco J.; Balabasquer, Moises; Gonzalo, Pilar; Khiar-Fernandez, Nora; Rolas, Loic; Barkaway, Anna; Nourshargh, Sussan; Andres, Vicente; Martin-Fontecha, Mar; Lopez-Rodriguez, Maria L.; Ortega-Gutierrez, Silvia 分享 收藏
Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery Huecas, Sonia; Araujo-Bazan, Lidia; Ruiz, Federico M.; Ruiz-Avila, Laura B.; Fernando Martinez, R.; Escobar-Pena, Andrea; Artola, Marta; Vazquez-Villa, Henar; Martin-Fontecha, Mar; Fernandez-Tornero, Carlos; Lopez-Rodriguez, Maria L.; Andreu, Jose M. 分享 收藏
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Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer Grunt, Thomas W.; Slany, Astrid; Semkova, Mariya; Colomer, Ramon; Luz Lopez-Rodriguez, Maria; Wuczkowski, Michael; Wagner, Renate; Gerner, Christopher; Stuebiger, Gerald 分享 收藏
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration Gonzalez-Gil, Ines; Zian, Debora; Vazquez-Villa, Henar; Hernandez-Torres, Gloria; Fernando Martinez, R.; Khiar-Fernandez, Nora; Rivera, Richard; Kihara, Yasuyuki; Devesa, Isabel; Mathivanan, Sakthikumar; Rosell del Valle, Cristina; Zambrana-Infantes, Emma; Puigdomenech, Maria; Cincilla, Giovanni; Sanchez-Martinez, Melchor; Rodriguez de Fonseca, Fernando; Ferrer-Montiel, Antonio, V; Chun, Jerold; Lopez-Vales, Ruben; Lopez-Rodriguez, Maria L.; Ortega-Gutierrez, Silvia 分享 收藏
Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells Bueno, Maria J.; Jimenez-Renard, Veronica; Samino, Sara; Capellades, Jordi; Junza, Alejandra; Luz Lopez-Rodriguez, Maria; Garcia-Carceles, Javier; Lopez-Fabuel, Irene; Bolanos, Juan P.; Chandel, Navdeep S.; Yanes, Oscar; Colomer, Ramon; Quintela-Fandino, Miguel 分享 收藏
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia Marin-Ramos, Nagore I.; Balabasquer, Moises; Ortega-Nogales, Francisco J.; Torrecillas, Ivan R.; Gil-Ordonez, Ana; Marcos-Ramiro, Beatriz; Aguilar-Garrido, Pedro; Cushman, Ian; Romero, Antonio; Medrano, Francisco J.; Gajate, Consuelo; Mollinedo, Faustino; Philips, Mark R.; Campillo, Mercedes; Gallardo, Miguel; Martin-Fontecha, Mar; Lopez-Rodriguez, Maria L.; Ortega-Gutierrez, Silvia 分享 收藏
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Development of a Fluorescent Bodipy Probe for Visualization of the Serotonin 5-H T1A Receptor in Native Cells of the Immune System Hernandez-Torres, Gloria; Enriquez-Palacios, Ernesto; Mecha, Miriam; Feliu, Ana; Rueda-Zubiaurre, Ainoa; Angelina, Alba; Martin-Cruz, Leticia; Martin-Fontecha, Mar; Palomares, Oscar; Guaza, Carmen; Pena-Cabrera, Eduardo; Lopez-Rodriguez, Maria L.; Ortega-Gutierrez, Silvia 分享 收藏
2-AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs 2-AG通过调节小胶质细胞和促进MDSCs来限制Theiler病毒诱导的急性神经炎症 Mecha, Miriam; Feliu, Ana; Machin, Isabel; Cordero, Cesar; Carrillo-Salinas, Francisco; Mestre, Leyre; Hernandez-Torres, Gloria; Ortega-Gutierrez, Silvia; Lopez-Rodriguez, Maria L.; de Castro, Fernando; Clemente, Diego; Guaza, Carmen 分享 收藏
A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells Martin-Fontecha, Mar; Angelina, Alba; Ruckert, Beate; Rueda-Zubiaurre, Ainoa; Martin-Cruz, Leticia; van de Veen, Willem; Akdis, Mubeccel; Ortega-Gutierrez, Silvia; Luz Lopez-Rodriguez, Maria; Akdis, Cezmi A.; Palomares, Oscar 分享 收藏
A Positive Allosteric Modulator of the Serotonin 5-HT2c Receptor for Obesity Garcia-Carceles, Javier; Decara, Juan M.; Vazquez-Villa, Henar; Rodriguez, Ramon; Codesido, Eva; Cruces, Jacobo; Brea, Jose; Loza, Maria I.; Alen, Francisco; Botta, Joaquin; McCormick, Peter J.; Ballesteros, Juan A.; Benhamu, Bellinda; Rodriguez de Fonseca, Fernando; Lopez-Rodriguez, Maria L. 分享 收藏
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A new serotonin 5-HT6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding Gonzalez-Vera, Juan A.; Medina, Rocio A.; Martin-Fontecha, Mar; Gonzalez, Angel; de la Fuente, Tania; Vazquez-Villa, Henar; Garcia-Carceles, Javier; Botta, Joaquin; McCormick, Peter J.; Benhamu, Bellinda; Pardo, Leonardo; Lopez-Rodriguez, Maria L. 分享 收藏
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