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J

James P. Cooney

Walter and Eliza Hall Institute of Medical Research
H指数:19
被引数:1,791

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Preclinical development of a cross-protective β-SARS-CoV-2 virus-like particle vaccine adjuvanted with MF59

以MF59为佐剂的交叉保护性 β-sars CoV-2病毒样颗粒疫苗的临床前开发

2026-01-170
OAAI
A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responses

一种新型嵌合冠状病毒刺突疫苗,结合了SARS-CoV-2 RBD和来自HKU-1的支架结构域,能够诱导强烈的中和抗体反应

2025-11-280
OAAI
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection

非凋亡型caspase-8对于调控严重SARS-CoV-2感染期间过度的炎症反应至关重要。

2025-11-130
OAAI
Combination antiretroviral therapy and MCL-1 inhibition mitigate HTLV-1 infection in vivo

联合抗逆转录病毒疗法和MCL-1抑制可减轻HTLV-1在体内的感染

Cell
IF42.5
2025-07-100
OAAI
Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice
2023-09-0113
OAAI
SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF- driven age- dependent severe disease with human correlates
2023-07-3111
OAAI
Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine

SARS-CoV-2受体结合域蛋白疫苗介导的对SARS-CoV-2相关变异的广泛免疫

2023-06-017
OAAI
Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 (vol 13, 889372, 2022)

Fc工程ACE2-Fc是一种有效的多功能剂靶向SARS-CoV2 (vol 13,889372,2022)

2023-01-100
OAAI
Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL -mediated Necroptosis From Contributing to Liver Pathologies
2022-12-0138
OA
Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2

Fc工程ACE2-Fc是一种有效的多功能药物靶向SARS-CoV2

2022-07-287
OAAI
Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors

洞察药物再利用,以及基于哌啶的SARS-CoV-2 PLpro抑制剂的特异性和复合特性

2022-04-1222
OAAI
Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage
2022-03-259
PRE
Interferon-g primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

干扰素-g通过caspase-8和线粒体细胞死亡途径引发巨噬细胞对病原体配体诱导的杀伤

IMMUNITY
IF26.3
2022-03-0185
OAAI
Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain
2021-10-0125
OAAI
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice
2021-04-2397
OA