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M

Marcel Doerflinger

walter and eliza hall institute of medical research
H指数:24
被引数:2,379

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Immunophenotype and proviral landscape of HTLV-1c infection and pulmonary disease

HTLV-1c感染的免疫表型和前病毒景观及其与肺部疾病的关系

EBioMedicine
IF10.8
2026-07-230
OAAI
Ashley Hirons; Natasha Jansz; Georges Khoury; Paula Ellenberg; Sarah Collins; James Cooney; John Zaunders; Lewis Williams; Kirthi Nandha Nair; Ashley Huey Yiing Yap; Nicholas Hirons; Liana Mackiewicz; Merle Dayton; Le Wang; Daniel Sijmons; Mohammad Radwanur Talukder; Allegra Holloway Vickas; Amy W. Chung; Marcel Doerflinger; Marc Pellegrini
Targeting rapidly cycling receptors CD2 and CD7 increases nanoparticle delivery to primary CD4+ T cells

靶向快速循环受体CD2和CD7可增强纳米颗粒向原代CD4+ T细胞的递送

Nature Communications
IF15.7
2026-07-010
OAAI
Paula M. Cevaal; Abdalla Ali; Marcel Doerflinger; Christina Cortez-Jugo; Abigail Tan; Haiyin Liu; Moore Z. Chen; Le Wang; Merle Dayton; Liana Mackiewicz; Stanislav Kan; Matthew Faria; Celine Gubser; René P. M. Lafleur; Robert De Rose; Angus P. R. Johnston; Frank Caruso; Michael Roche; Jori Symons; Sharon R. Lewin
Efferocytosis of apoptotic bodies drives SARS-CoV-2 infection and macrophage inflammation

凋亡小体清除作用驱动SARS-CoV-2感染和巨噬细胞炎症

Nature Communications
IF15.7
2026-06-150
OAAI
Thanh Kha Phan; Dylan Sheerin; Bo Shi; Ngee K. Chua; Sriram Gummadi; Merle Dayton; Liana Mackiewicz; Ana Maluenda; Dilara C. Ozkocak; Georgia K. Atkin-Smith; Nashied Peton; Ching-Seng Ang; Omar Audi; Quan Thinh Le; Thu Uyen Tran; Tuong-Khanh My Tu; Rochelle Tixeira; George W. Ashdown; Kathryn C. Davidson; Pamali Fonseka; Rebecca Feltham; Marcel Doerflinger; Mark D. Hulett; Anna K. Coussens; Ivan K. H. Poon
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection

非凋亡型caspase-8对于调控严重SARS-CoV-2感染期间过度的炎症反应至关重要。

Nature Communications
IF15.7
2025-11-130
OAAI
Stefanie M. Bader; Lena Scherer; Reet Bhandari; Allan J. Motyer; James P. Cooney; Liana Mackiewicz; Merle Dayton; Dylan Sheerin; David V. L. Romero; Jan Schaefer; Jiyi Pang; Siqi Chen; Kael Schoffer; Le Wang; Xinyi Jin; Daniel Batey; Raymond K. H. Yip; Ishrat Zaman; Pradeep Rajasekhar; Matthew J. Gartner; Stephen Wilcox; Lachlan Whitehead; Smitha Rose Georgy; Ana Maluenda; Kathryn C. Davidson; Cody C. Allison; Rory Bowden; Kerstin Brinkmann; Marie-Liesse Asselin-Labat; Belinda Phipson; Maria C. Tanzer; Marco J. Herold; Andre L. Samson; James E. Vince; Andreas Strasser; Marc Pellegrini; Marcel Doerflinger
Paternal SARS-CoV-2 infection impacts sperm small noncoding RNAs and increases anxiety in offspring in a sex-dependent manner

父系SARS-CoV-2感染影响精子小非编码RNA，并表现出性别依赖性地增加子代焦虑水平。

Nature Communications
IF15.7
2025-10-110
OAAI
Elizabeth A. Kleeman; Carolina Gubert; Sonali N. Reisinger; Kathryn C. Davidson; Da Lu; Merle Dayton; Liana Mackiewicz; Bethany A. Masson; Pranav Adithya; Alexandra L. Garnham; Gemma Stathatos; Moira K. O’Bryan; Rikeish R. Muralitharan; Francine Z. Marques; Shanshan Li; Huan Liao; Shae McLaughlin; Emmet T. Keough; Michelle Y. Wheeler; Pamudika Kiridena; Marcel Doerflinger; Marc Pellegrini; Anthony J. Hannan
Elucidating novel immune profiles for predicting infection in high-risk cohorts: a pilot study in patients with relapsed and refractory chronic lymphocytic leukaemia

阐明预测高危人群感染的新的免疫谱：复发和难治性慢性淋巴细胞白血病患者的一项初步研究

Clinical & Translational Immunology
IF3.8
2025-08-030
OAAI
Lewis J Williams; Connie SN Li-Wai-Suen; Alex L Garnham; Stefanie M Bader; Constantine S Tam; Ashley Whitechurch; Monica A Slavin; Marcel Doerflinger; Benjamin W Teh
Combination antiretroviral therapy and MCL-1 inhibition mitigate HTLV-1 infection in vivo

联合抗逆转录病毒疗法和MCL-1抑制可减轻HTLV-1在体内的感染

Cell
IF42.5
2025-07-100
OAAI
James P. Cooney; Ashley Hirons; Natasha Jansz; Cody C. Allison; Peter Hickey; Charis E. Teh; Tania Tan; Laura F. Dagley; Jumana Yousef; David Yurick; Georges Khoury; Simon P. Preston; Philip Arandjelovic; Kathryn C. Davidson; Lewis J. Williams; Stefanie M. Bader; Le Wang; Reet Bhandari; Liana Mackiewicz; Merle Dayton; William Clow; Geoffrey J. Faulkner; Daniel H. Gray; Lloyd Einsiedel; Damian F.J. Purcell; Marcel Doerflinger; Marc Pellegrini
NLRP3 inflammasome–driven hemophagocytic lymphohistiocytosis occurs independent of IL-1β and IL-18 and is targetable by BET inhibitors

NLRP3炎性小体驱动的噬血细胞性淋巴组织细胞增多症的发生与IL-1β和IL-18无关，且可被BET抑制剂靶向治疗。

Science Advances
IF12.5
2025-07-090
PREAI
Farzaneh Shojaee; Esmaeel Azadian; Min Xian Wong; Xiuquan Ma; James Rickard; Jiyi Pang; Catherine Hall; Andrew J. Kueh; Seth L. Masters; Inmaculada Rioja; Rab K. Prinjha; Marcel Doerflinger; Kate E. Lawlor; Maryam Rashidi; James E. Vince
Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs against RNA viruses

代谢建模阐明了苯氟丙脲和atpenin A5作为广谱抗RNA病毒药物。

COMMUNICATIONS BIOLOGY
IF5.1
2025-05-230
OA
Renz, Alina; Hohner, Mirjam; Jami, Raphael; Breitenbach, Maximilian; Josephs-Spaulding, Jonathan; Duerrwald, Johanna; Best, Lena; Duliere, Victoria; Mialon, Chloe; Bader, Stefanie M.; Marinos, Georgios; Leonidou, Nantia; Cabreiro, Filipe; Pellegrini, Marc; Doerflinger, Marcel; Rosa-Calatrava, Manuel; Pizzorno, Andres; Draeger, Andreas; Schindler, Michael; Kaleta, Christoph
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

常见的人类MLKL多态性赋予对磷酸化负调控的抗性

NATURE COMMUNICATIONS
IF15.7
2023-09-286
OAAI
Garnish, Sarah E.; Martin, Katherine R.; Kauppi, Maria; Jackson, Victoria E.; Ambrose, Rebecca; Eng, Vik Ven; Chiou, Shene; Meng, Yanxiang; Frank, Daniel; Crutchfield, Emma C. Tovey; Patel, Komal M.; Jacobsen, Annette V.; Atkin-Smith, Georgia K.; Di Rago, Ladina; Doerflinger, Marcel; Horne, Christopher R.; Hall, Cathrine; Young, Samuel N.; Cook, Matthew; Athanasopoulos, Vicki; Vinuesa, Carola G.; Lawlor, Kate E.; Wicks, Ian P.; Ebert, Gregor; Ng, Ashley P.; Slade, Charlotte A.; Pearson, Jaclyn S.; Samson, Andre L.; Silke, John; Murphy, James M.; Hildebrand, Joanne M.
Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice
CELL REPORTS MEDICINE
IF10.6
2023-09-0113
OAAI
Arandjelovic, Philip; Kim, Youry; Cooney, James P.; Preston, Simon P.; Doerflinger, Marcel; Mcmahon, James H.; Garner, Sarah E.; Zerbato, Jennifer M.; Roche, Michael; Tumpach, Carolin; Ong, Jesslyn; Sheerin, Dylan; Smyth, Gordon K.; Anderson, Jenny L.; Allison, Cody C.; Lewin, Sharon R.; Pellegrini, Marc
SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF- driven age- dependent severe disease with human correlates
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-07-3111
OAAI
Bader, Stefanie M.; Cooney, James P.; Sheerin, Dylan; Taiaroa, George; Harty, Leigh; Davidson, Kathryn C.; Mackiewicz, Liana; Dayton, Merle; Wilcox, Stephen; Whitehead, Lachlan; Rogers, Kelly L.; Georgy, Smitha Rose; Coussens, Anna K.; Grimley, Samantha L.; Corbin, Vincent; Pitt, Miranda; Coin, Lachlan; Pickering, Raelene; Thomas, Merlin; Allison, Cody C.; McAuley, Julie; Purcell, Damian F. J.; Doerflinger, Marcel; Pellegrini, Marc

研究方向

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M
Marc Pellegrini
H 指数:49论文数:174被引数:1.0万
L
Liana Mackiewicz
H 指数:11论文数:31被引数:487
C
Cody C. Allison
H 指数:26论文数:65被引数:3,032
J
James P. Cooney
H 指数:19论文数:74被引数:1,791
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Hamsa Puthalakath
H 指数:37论文数:92被引数:1.7万
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Marco J. Herold
H 指数:58论文数:416被引数:1.3万
S
Stefanie M. Bader
H 指数:14论文数:36被引数:863
A
Andreas Strasser
H 指数:135论文数:816被引数:8.4万
M
Merle Dayton
H 指数:6论文数:25被引数:237
S
Simon Preston
H 指数:23论文数:48被引数:4,459