未登录Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway西红花酸通过STK11/LKB1-mediated AMPK途径诱导自噬促进 β 淀粉样蛋白清除
Wani, Abubakar; Al Rihani, Sweilem B.; Sharma, Ankita; Weadick, Brenna; Govindarajan, Rajgopal; Khan, Sameer U.; Sharma, Parduman R.; Dogra, Ashish; Nandi, Utpal; Reddy, Chilakala N.; Bharate, Sonali S.; Singh, Gurdarshan; Bharate, Sandip B.; Vishwakarma, Ram A.; Kaddoumi, Amal; Kumar, Ajay
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收藏Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
Wani, Abubakar; Gupta, Mehak; Ahmad, Masroor; Shah, Aabid M.; Ahsan, Aitizaz Ul; Qazi, Parvaiz H.; Malik, Fayaz; Singh, Gurdarshan; Sharma, Parduman R.; Kaddoumi, Amal; Bharate, Sandip B.; Vishwakarma, Ram A.; Kumar, Ajay
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收藏The amino analogue of β-boswellic acid efficiently attenuates the release of pro-inflammatory mediators than its parent compound through the suppression of NF-κB/IκBα signalling axis
Gupta, Shilpa; Ul Ahsan, Aitizaz; Wani, Abubakar; Khajuria, Vidushi; Nazir, Lone A.; Sharma, Simmi; Bhagat, Asha; Sharma, Parduman Raj; Bhardwaj, Subhash; Peerzada, Kaiser J.; Shah, Bhahwal Ali; Ahmed, Zabeer
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收藏Dual role of Par-4 in abrogation of EMT and switching on Mesenchymal to Epithelial Transition (MET) in metastatic pancreatic cancer cells
Katoch, Archana; Suklabaidya, Sujit; Chakraborty, Souneek; Nayak, Debasis; Rasool, Reyaz U.; Sharma, Deepak; Mukherjee, Debaraj; Faheem, Mir M.; Kumar, Anmol; Sharma, Parduman R.; Senapati, Shantibhusan; Kumar, Lekha D.; Goswami, Anindya
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收藏Development and characterization of hyaluronic acid modified PLGA based nanoparticles for improved efficacy of cisplatin in solid tumor
Alam, Noor; Koul, Mytre; Mintoo, Mubashir J.; Khare, Vaibhav; Gupta, Rahul; Rawat, Neha; Sharma, Parduman Raj; Singh, Shashank K.; Mondhe, Dilip M.; Gupta, Prem N.
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收藏Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and Intracellular Invasion of Bacteria
Singh, Samsher; Kalia, Nitin P.; Joshi, Prashant; Kumar, Ajay; Sharma, Parduman R.; Kumar, Ashok; Bharate, Sandip B.; Khan, Inshad A.
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收藏Anti-inflammatory potential of hentriacontane in LPS stimulated RAW 264.7 cells and mice model
Khajuria, Vidushi; Gupta, Shilpa; Sharma, Neha; Kumar, Ashok; Lone, Nazir A.; Khullar, Mowkshi; Dutt, Prabhu; Sharma, Parduman Raj; Bhagat, Asha; Ahmed, Zabeer
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收藏Exploring Derivatives of Quinazoline Alkaloid L-Vasicine as Cap Groups in the Design and Biological Mechanistic Evaluation of Novel Antitumor Histone Deacetylase Inhibitors
Ahmad, Mudassier; Aga, Mushtaq A.; Bhat, Javeed Ahmad; Kumar, Brijesh; Rouf, Abdul; Capalash, Neena; Mintoo, Mubashir Javeed; Kumar, Ashok; Mahajan, Priya; Mondhe, Dilip Manikrao; Nargotraill, Amit; Sharma, Parduman Raj; Zargar, Mohmmad Afzal; Vishwakarma, Ram A.; Shah, Bhahwal Ali; Taneja, Subhash Chandra; Hamid, Abid
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收藏Interplay between cell cycle and autophagy induced by boswellic acid analog
Pathania, Anup S.; Guru, Santosh K.; Kumar, Suresh; Kumar, Ashok; Ahmad, Masroor; Bhushan, Shashi; Sharma, Parduman R.; Mahajan, Priya; Shah, Bhahwal A.; Sharma, Simmi; Nargotra, Amit; Vishwakarma, Ram; Korkaya, Hasan; Malik, Fayaz
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收藏Modulation of glycolysis and lipogenesis by novel PI3K selective molecule represses tumor angiogenesis and decreases colorectal cancer growth
Hussain, Aashiq; Qazi, Asif Khurshid; Mupparapu, Nagaraju; Guru, Santosh Kumar; Kumar, Ashok; Sharma, Parduman Raj; Singh, Shashank Kumar; Singh, Paramjit; Dar, Mohd Jamal; Bharate, Sandip B.; Zargar, Mohmmad Afzal; Ahmed, Qazi Naveed; Bhushan, Shashi; Vishwakarma, Ram A.; Hamid, Abid
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收藏A novel PI3K axis selective molecule exhibits potent tumor inhibition in colorectal carcinogenesis一种新的PI3K轴选择性分子在结直肠癌发生中表现出有效的肿瘤抑制作用
Hussain, Aashiq; Qazi, Asif Khurshid; Mupparapu, Nagaraju; Kumar, Ashok; Mintoo, Mubashir Javeed; Mahajan, Girish; Sharma, Parduman Raj; Singh, Shashank Kumar; Bharate, Sandip B.; Zargar, Mohmmad Afzal; Ahmed, Qazi Naveed; Mondhe, Dilip Manikrao; Vishwakarma, Ram A.; Hamid, Abid
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收藏A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells
Wani, Zahoor Ahmad; Guru, Santosh Kumar; Rao, A. V. Subba; Sharma, Sonia; Mahajan, Girish; Behl, Akanksha; Kumar, Ashok; Sharma, P. R.; Kamal, Ahmed; Bhushan, Shashi; Mondhe, Dilip M.
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收藏Reduced toxicological manifestations of cisplatin following encapsulation in folate grafted albumin nanoparticles
Alam, Noor; Dubey, Ravindra Dhar; Kumar, Ashok; Koul, Mytre; Sharma, Neelam; Sharma, Parduman Raj; Chandan, Bal Krishan; Singh, Shashank K.; Singh, Gurdarshan; Gupta, Prem N.
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收藏Identification and characterization of novel small molecule inhibitors of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU)大肠杆菌N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU) 乙酰转移酶活性新型小分子抑制剂的鉴定与表征
Sharma, Rashmi; Rani, Chitra; Mehra, Rukmankesh; Nargotra, Amit; Chib, Reena; Rajput, Vikrant S.; Kumar, Sunil; Singh, Samsher; Sharma, Parduman R.; Khan, Inshad A.
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收藏Development and evaluation of folate functionalized albumin nanoparticles for targeted delivery of gemcitabine用于吉西他滨靶向递送的叶酸功能化白蛋白纳米粒的研制与评价
Dubey, Ravindra Dhar; Alam, Noor; Saneja, Ankit; Khare, Vaibhav; Kumar, Ashok; Vaidh, Shagun; Mahajan, Girish; Sharma, Parduman R.; Singh, Shashank K.; Mondhe, Dilip M.; Gupta, Prem N.
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收藏Secalonic Acid-D Represses HIF1α/VEGF-Mediated Angiogenesis by Regulating the Akt/mTOR/p70S6K Signaling Cascade
Guru, Santosh Kumar; Pathania, Anup Singh; Kumar, Suresh; Ramesh, Deshidi; Kumar, Manjeet; Rana, Satiander; Kumar, Ajay; Malik, Fayaz; Sharma, P. R.; Chandan, B. K.; Jaglan, Sundeep; Sharma, J. P.; Shah, Bhahwal Ali; Tasduq, Sheikh Abdullah; Lattoo, Surrinder K.; Faruk, Abdul; Saxena, A. K.; Vishwakarma, R. A.; Bhushan, Shashi
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收藏Par-4 dependent modulation of cellular -catenin by medicinal plant natural product derivative 3-azido Withaferin A药用植物天然产物衍生物3-叠氮基witaferin A对细胞连环蛋白的Par-4依赖性调节
Amin, Hina; Nayak, Debasis; Rasool, Reyaz Ur; Chakraborty, Souneek; Kumar, Anmol; Yousuf, Khalid; Sharma, Parduman Raj; Ahmed, Zabeer; Sharma, Neelam; Magotra, Asmita; Mukherjee, Debaraj; Kumar, Lekha Dinesh; Goswami, Anindya
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