王

王巍 (Wei Wang)

Sichuan University

H指数:30

被引数:5,096

个人简介

任职于武汉大学药学院。2000年获武汉大学化学系学士学位，2005年获武汉大学理学博士学位。2005年至2006年任上海无锡药明康德新药开发有限公司高级研究员，2006年至2008年在美国南伊利诺斯大学从事博士后研究，2008年至2011年在美国匹兹堡大学从事博士后研究，2011年至今在武汉大学药学院工作。

教育背景

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工作经历

暂无内容

荣誉奖项

暂无内容

Photo-induced carboxylation of C(sp2)-S bonds in aryl thiols and derivatives with CO2

芳基硫醇及其衍生物中C(sp2)-S键与CO2的光诱导羧化

NATURE COMMUNICATIONS

IF15.7

2024-11-220

OAAI

N-Fluorosulfonyl Guanidine: An Entry to N-Guanyl Sulfamides and Sulfamates

ORGANIC LETTERS

IF5

2024-04-054

PRE

Mendelian randomization study reveals the relationship between dietary factors and respiratory diseases (vol 13, 22601, 2023)

SCIENTIFIC REPORTS

IF3.9

2024-02-190

OAAI

AOG-LSTM: An adaptive attention neural network for visual storytelling

NEUROCOMPUTING

IF6.5

2023-10-014

PRE

Frequency-dependent functional alterations in people living with HIV with early stage of HIV-associated neurocognitive disorder

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-01-092

OAAI

Practical Strategy to 1,1′-Dideoxygossypol Derivatives from Gossypol and Its Antitumor Activities

ACS OMEGA

IF4.3

2022-06-221

OAAI

Short-brush NiFeOxHy films and the Pt derivative as high-performance electrode materials for efficient electrocatalytic water splitting

APPLIED SURFACE SCIENCE

IF6.9

2022-02-019

PRE

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration (vol 10, 4059, 2019)

NATURE COMMUNICATIONS

IF15.7

2021-10-280

OAAI

Two Birds with One Stone: NFAT1-MDM2 Dual Inhibitors for Cancer Therapy

CELLS

IF5.2

2020-05-0910

OAAI

Cu-Catalyzed Selective Oxy-Cyanoalkylation of Allylamines with Cycloketone Oxime Esters and CO2

CHINESE JOURNAL OF CHEMISTRY

IF5.5

2019-11-2535

PREAI

Targeting MDM2 for novel molecular therapy: Beyond oncology

MEDICINAL RESEARCH REVIEWS

IF11.6

2019-10-0665

OAAI

Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine

GENES & DISEASES

IF9.4

2018-09-0175

OAAI

Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms

CARCINOGENESIS

IF2.9

2018-05-1223

OAAI

Feature-derived graph regularized matrix factorization for predicting drug side effects

NEUROCOMPUTING

IF6.5

2018-04-0173

PREAI

The linear neighborhood propagation method for predicting long non-coding RNA - protein interactions

NEUROCOMPUTING

IF6.5

2018-01-01140

PREAI

Recent advances in gossypol derivatives and analogs: a chemistry and biology view

FUTURE MEDICINAL CHEMISTRY

IF3.4

2017-07-1944

PREAI

Establishment and observation of a new and ideal reversible model of PUUO

RENAL FAILURE

IF3

2016-11-151

OAAI

Gossypol with Hydrophobic Linear Esters Exhibits Enhanced Antitumor Activity as an Inhibitor of Antiapoptotic Proteins

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2016-10-2421

OAAI

Isocyanides as InfluenzaA Virus Subtype H5N1 Wild-Type M2 Channel Inhibitors

CHEMMEDCHEM

IF3.4

2015-09-0720

OAAI

Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery

CELL CYCLE

IF3.4

2014-10-27232

PREAI

研究方向

抗病毒药物设计与发现肿瘤蛋白相互作用靶点药物设计蛋白蛋白相互作用功能小分子药物设计与合成多组分反应多肽拟肽合成药物化学研究有机合成反应不对称合成反应技术药物合成多组分反应化学骨架数据库化合物库构建基于细胞内信号传导和结构生物学的生物活性分子化合物设计药物设计蛋白蛋白相互作用调节剂多组分化合物库合成高通量筛选研究