Peter J. Little - Publications, H-index & Citations

Peter J. Little

Sun Yat sen University

66H指数

426论文数

1.6W被引数

收录论文 158

发表时间

Hepatic IFRD1 suppresses metabolic dysfunction-associated fatty liver disease via GLUD1/α-KG axis 肝IFRD1通过GLUD1/α-KG轴抑制代谢功能障碍相关脂肪肝

Science Bulletin

IF21.1

2026-04-06

PREAI

Mengya Geng; Fanzheng Meng; Hairui Li; Lijie Sun; Xuedan Sun; Yu Ding; Rongdongqing Shi; Zhihua Wang; Yabin Huang; Jizhou Wang; Yao Liu; Jiabei Wang; Peter J. Little; Suowen Xu; Lianxin Liu; Jianping Weng; Sihui Luo

GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity GLM7——一种新型的复合糖脂指数，该指数基于常规健康指标，用于提高对多病共存症的诊断和预测能力。

Advanced Science

IF14.1

2025-08-28

OAAI

Zhihua Wang; Shuo Chen; Xiaojun Feng; Xi Chen; Paul C Evans; Hans Strijdom; Yu Ding; Jianping Weng; Suowen Xu

Isoginkgetin, a natural biflavonoid from Ginkgo biloba, inhibits inflammatory response in endothelial cells via suppressing NF-κB activation Isoginkgetin，一种从Ginkgo biloba中提取的天然双黄酮类化合物，通过抑制NF-κB的激活来抑制内皮细胞中的炎症反应。

Acta Pharmacologica Sinica

IF8.4

2025-07-16

PREAI

Mei-jie Chen; Zhi-dan Zhang; Fan-shun Zhang; Paul C. Evans; Hans Strijdom; Suo-wen Xu

Targeting mitochondrial DNA-STING-NF-κB Axis-mediated microglia activation by cryptotanshinone alleviates ischemic retinopathy 通过cryptotanshinone靶向线粒体DNA-STING-NF-κB轴介导的小胶质细胞活化，可缓解缺血性视网膜病变

PHYTOMEDICINE

IF8.3

2025-07-01

PREAI

Qiu, Wanlu; Zheng, Zhihua; Wang, Jiaojiao; Cai, Youran; Zou, Jiami; Huang, Ziqing; Yang, Pinglian; Ye, Weile; Jin, Mei; Zhang, Dongmei; Little, Peter J.; Zhou, Qing

The novel effects of Aspalathus linearis (Rooibos) against angiotensin-II-induced hypertrophy in H9C2 cardiomyoblasts Aspalathus linearis（Rooibos）对血管紧张素-II诱导的H9C2心肌成纤维细胞肥大产生的 novel effects

South African Journal of Botany

IF2.7

2025-06-07

OAAI

TM Kgatla; S Shaboodien; MS Parker; H Strijdom; J Lopes; E Marais; G Maarman

HIV infection, antiretroviral therapy and vascular dysfunction: Effects, mechanisms and treatments HIV感染、抗逆转录病毒治疗与血管功能障碍：效应、机制及治疗

Pharmacological Research

IF10.5

2025-06-01

OAAI

Shulin Wei; Paul C. Evans; Hans Strijdom; Suowen Xu

Revisiting the role of GDF15 in atherosclerosis in mouse and human 重新审视GDF15在动脉粥样硬化中的小鼠和人类中的作用

ACTA PHARMACOLOGICA SINICA

IF8.4

2025-04-30

PREAI

Liu, MN; Liu, ZH; Leng, RX; Strijdom, H; Weng, JP; Xu, SW

Endothelial Dysfunction Markers Correlate with the Time Since Completion of Tuberculosis Treatment and the Number of Previous Tuberculosis Episodes

INFECTIOUS DISEASE REPORTS

IF2.4

2025-02-28

OAAI

Jumaar, Chrisstoffel; Jacobs, Steve; Payne, Carmen; Sanni, Olakunle; Louw, Elize; Baines, Nicola; Maree, David; Botha, Benjamin; Feyasa, Merga Belina; Strijdom, Hans; Allwood, Brian; Maarman, Gerald J.

Aclysiran, an RNAi therapeutic agent targeting ACLY, treats hypercholesterolemia and atherosclerosis in ApoE-/- mice Aclysiran，一种靶向ACLY的RNAi治疗剂，可治疗ApoE-/-小鼠的高胆固醇血症和动脉粥样硬化。

ACTA PHARMACEUTICA SINICA B

IF14.6

2024-12-01

OAAI

Chen, MJ; Little, PJ; Kong, SD; Banach, M; Weng, JP; Xu, SW

Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-11-06

OAAI

Chia, Zheng-Jie; Kumarapperuma, Hirushi; Zhang, Ruizhi; Little, Peter J.; Kamato, Danielle

Response to retention hypothesis as a source of targets for arterial wall-directed therapies to prevent atherosclerosis: A critical review

ATHEROSCLEROSIS

IF5.7

2024-10-01

OAAI

Kumarapperuma, Hirushi; Chia, Zheng-Jie; Malapitan, Sanchia Marie; Wight, Thomas N.; Little, Peter J.; Kamato, Danielle

Targeting the smooth muscle cell KEAP1-Nrf2-STING axis with pterostilbene attenuates abdominal aortic aneurysm 用紫檀芪靶向平滑肌细胞KEAP1-Nrf2-STING轴减轻腹主动脉瘤

PHYTOMEDICINE

IF8.3

2024-07-01

PREAI

Zou, Jiami; Zheng, Zhihua; Ye, Weile; Jin, Mei; Yang, Pinglian; Little, Peter J.; Wang, Jiaojiao; Liu, Zhiping

Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-04-08

PREAI

Ni, Xia-yun; Feng, Xiao-jun; Wang, Zhi-hua; Zhang, Yang; Little, Peter J.; Cao, Yang; Xu, Suo-wen; Tang, Li-qin; Weng, Jian-ping

Mechanistic insight: Linking cardiovascular complications of inflammatory bowel disease

TRENDS IN CARDIOVASCULAR MEDICINE

IF9

2024-04-01

OAAI

Kumarapperuma, Hirushi; Wang, Ran; Little, Peter J.; Kamato, Danielle

The cytoplasmic sensor, the AIM2 inflammasome: A precise therapeutic target in vascular and metabolic diseases 细胞质传感器，AIM2炎性体: 血管和代谢疾病的精确治疗靶标

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2024-03-25

PREAI

Lin, Jiuguo; Wang, Jiaojiao; Fang, Jian; Li, Meihang; Xu, Suowen; Little, Peter J.; Zhang, Dongmei; Liu, Zhiping

A novel mouse model of familial combined hyperlipidemia and atherosclerosis 一种新的家族性高脂血症和动脉粥样硬化小鼠模型

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-03-08

PREAI

Chen, Mei-jie; Xu, Yi-tong; Sun, Lu; Wang, Zhi-hua; Little, Peter J.; Wang, Li; Xian, Xun-de; Weng, Jian-ping; Xu, Suo-wen

Transforming growth factor-β receptors: versatile mechanisms of ligand activation

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-02-13

OAAI

Chia, Zheng-Jie; Cao, Ying-nan; Little, Peter J.; Kamato, Danielle

A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection

PHARMACOLOGICAL RESEARCH

IF10.5

2024-01-01

OAAI

Jiang, Hui; Zhao, Yaping; Su, Meiming; Sun, Lu; Chen, Meijie; Zhang, Zhidan; Ilyas, Iqra; Wang, Zhihua; Little, Peter J.; Wang, Li; Weng, Jianping; Ge, Jianjun; Xu, Suowen

Animal models of heart failure with preserved ejection fraction (HFpEF): from metabolic pathobiology to drug discovery

ACTA PHARMACOLOGICA SINICA

IF8.4

2023-08-29

PREAI

Gao, Si; Liu, Xue-ping; Li, Ting-ting; Chen, Li; Feng, Yi-ping; Wang, Yu-kun; Yin, Yan-jun; Little, Peter J.; Wu, Xiao-qian; Xu, Suo-wen; Jiang, Xu-dong

Immunologic and vascular biomarkers of mortality in critical COVID-19 in a South African cohort

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-07-03

OAAI

Shaw, Jane Alexandra; Meiring, Maynard; Snyders, Candice; Everson, Frans; Sigwadhi, Lovemore Nyasha; Ngah, Veranyay; Tromp, Gerard; Allwood, Brian; Koegelenberg, Coenraad F. N.; Irusen, Elvis M.; Lalla, Usha; Baines, Nicola; Zemlin, Annalise E.; Erasmus, Rajiv T.; Chapanduka, Zivanai C.; Matsha, Tandi E.; Walzl, Gerhard; Strijdom, Hans; du Plessis, Nelita; Zumla, Alimuddin; Chegou, Novel; Malherbe, Stephanus T.; Nyasulu, Peter S.

研究方向