John Heap - Publications, H-index & Citations

John Heap

London School of Hygiene & Tropical Medicine

30H指数

197论文数

5.1K被引数

收录论文 30

发表时间

Modular Combinatorial DNA Assembly of Group B Streptococcus Capsular Polysaccharide Biosynthesis Pathways to Expediate the Production of Novel Glycoconjugate Vaccines 模块化组合DNA组装法用于构建B族链球菌荚膜多糖生物合成途径，以加速新型糖蛋白偶联疫苗的生产

VACCINES

IF3.4

2025-03-06

OAAI

Harrison, Mark A.; Atkins, Elizabeth; Faulds-Pain, Alexandra; Heap, John T.; Wren, Brendan W.; Passmore, Ian J.

Scalable Bioreactor Production of an O2-Protected [FeFe]-Hydrogenase Enables Simple Aerobic Handling for Clean Chemical Synthesis

CHEMCATCHEM

IF3.9

2024-04-26

OAAI

Cleary, Sarah E.; Hall, Stephen J.; Galan-Bataller, Regina; Lurshay, Tara C.; Hancox, Charlotte; Williamson, James J.; Heap, John T.; Reeve, Holly A.; Morra, Simone

Developing a genetic engineering method for Acetobacterium wieringae to expand one-carbon valorization pathways 开发维林氏醋酸杆菌的基因工程方法以扩展一碳增值途径

BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS

IF4.6

2023-02-14

OAAI

Moreira, Joao P. C.; Heap, John T.; Alves, Joana I.; Domingues, Lucilia

A combinatorial DNA assembly approach to biosynthesis of N-linked glycans in E. coli 在大肠杆菌中生物合成N-连接聚糖的组合DNA组装方法

GLYCOBIOLOGY

IF3.3

2023-01-13

OAAI

Passmore, Ian J.; Faulds-Pain, Alexandra; Abouelhadid, Sherif; Harrison, Mark A.; Hall, Catherine L.; Hitchen, Paul; Dell, Anne; Heap, John T.; Wren, Brendan W.

A primer to directed evolution: current methodologies and future directions

RSC CHEMICAL BIOLOGY

IF3.1

2023-01-01

OAAI

Selles Vidal, Lara; Isalan, Mark; Heap, John T.; Ledesma-Amaro, Rodrigo

Versatile selective evolutionary pressure using synthetic defect in universal metabolism

NATURE COMMUNICATIONS

IF15.7

2021-11-25

OAAI

Vidal, Lara Selles; Murray, James W.; Heap, John T.

Combinatorial assembly platform enabling engineering of genetically stable metabolic pathways in cyanobacteria

NUCLEIC ACIDS RESEARCH

IF13.1

2021-09-23

OAAI

Taylor, George M.; Hitchcock, Andrew; Heap, John T.

Type IV Pili-Independent Photocurrent Production by the Cyanobacterium Synechocystis sp. PCC 6803 蓝藻集胞藻属sp。PCC 6803的IV型菌毛独立光电流产生

FRONTIERS IN MICROBIOLOGY

IF4.5

2020-06-25

OAAI

Thirumurthy, Miyuki A.; Hitchcock, Andrew; Cereda, Angelo; Liu, Jiawei; Chavez, Marko S.; Doss, Bryant L.; Ros, Robert; El-Naggar, Mohamed Y.; Heap, John T.; Bibby, Thomas S.; Jones, Anne K.

VAPPER: High-throughput variant antigen profiling in African trypanosomes of livestock

GIGASCIENCE

IF3.9

2019-08-29

OAAI

Pereira, Sara Silva; Heap, John; Jones, Andrew R.; Jackson, Andrew P.

Transcriptional Terminators Allow Leak-Free Chromosomal Integration of Genetic Constructs in Cyanobacteria

MICROORGANISMS

IF4.2

2019-08-16

OAAI

Kelly, Ciaran L.; Taylor, George M.; Satkute, Aiste; Dekker, Linda; Heap, John T.

Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering

NUCLEIC ACIDS RESEARCH

IF13.1

2018-11-20

OAAI

Taylor, George M.; Mordaka, Pawel M.; Heap, John T.

Synthetic negative feedback circuits using engineered small RNAs

NUCLEIC ACIDS RESEARCH

IF13.1

2018-09-13

OAAI

Kelly, Ciaran L.; Harris, Andreas W. K.; Steel, Harrison; Hancock, Edward J.; Heap, John T.; Papachristodoulou, Antonis

The Butanol Producing Microbe Clostridium beijerinckii NCIMB 14988 Manipulated Using Forward and Reverse Genetic Tools

BIOTECHNOLOGY JOURNAL

IF3.1

2018-04-29

OAAI

Little, Gareth T.; Willson, Benjamin J.; Heap, John T.; Winzer, Klaus; Minton, Nigel P.

A Rhamnose-Inducible System for Precise and Temporal Control of Gene Expression in Cyanobacteria 鼠李糖诱导系统，用于精确和时间控制蓝细菌中的基因表达

ACS SYNTHETIC BIOLOGY

IF3.9

2018-03-15

OAAI

Kelly, Ciaran L.; Taylor, George M.; Hitchcock, Andrew; Torres-Mendez, Antonio; Heap, John T.

Stringency of Synthetic Promoter Sequences in Clostridium Revealed and Circumvented by Tuning Promoter Library Mutation Rates

ACS SYNTHETIC BIOLOGY

IF3.9

2018-01-26

OAAI

Mordaka, Pawel M.; Heap, John T.

Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability

SCIENTIFIC REPORTS

IF3.9

2017-12-13

OAAI

Jain, Shailesh; Smyth, Deborah; O'Hagan, Barry M. G.; Heap, John T.; McMullan, Geoff; Minton, Nigel P.; Ternan, Nigel G.

In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-10-01

OAAI

Miari, Victoria F.; Solanki, Priya; Hieba, Yonek; Stabler, Richard A.; Heap, John T.

6-Deoxyhexoses from l-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2016-07-21

OAAI

Liu, Zilei; Yoshihara, Akihide; Kelly, Ciaran; Heap, John T.; Marqvorsen, Mikkel H. S.; Jenkinson, Sarah F.; Wormald, Mark R.; Otero, Jose M.; Estevez, Amalia; Kato, Atsushi; Fleet, George W. J.; Estevez, Ramon J.; Izumori, Ken

Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the rhaBAD Promoter

ACS SYNTHETIC BIOLOGY

IF3.9

2016-06-21

OAAI

Kelly, Ciaran L.; Liu, Zilei; Yoshihara, Akihide; Jenkinson, Sarah F.; Wormald, Mark R.; Otero, Jose; Estevez, Amalia; Kato, Atsushi; Marqvorsen, Mikkel H. S.; Fleet, George W. J.; Estevez, Ramon J.; Izumori, Ken; Heap, John T.

Mutant generation by allelic exchange and genome resequencing of the biobutanol organism Clostridium acetobutylicum ATCC 824

BIOTECHNOLOGY FOR BIOFUELS

IF6.1

2016-01-04

OAAI

Ehsaan, Muhammad; Kuit, Wouter; Zhang, Ying; Cartman, Stephen T.; Heap, John T.; Winzer, Klaus; Minton, Nigel P.

研究方向