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Paul D. Roepe

Georgetown University

49H指数
187论文数
8.6K被引数
收录论文 46
发表时间
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Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology
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IF4.7
err2024-01-16
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errHagenah, Laura M.; Dhingra, Satish K.; Small-Saunders, Jennifer L.; Qahash, Tarrick; Willems, Andreas; Schindler, Kyra A.; Rangel, Gabriel W.; Gil-Iturbe, Eva; Kim, Jonathan; Akhundova, Emiliya; Yeo, Tomas; Okombo, John; Mancia, Filippo; Quick, Matthias; Roepe, Paul D.; Llinas, Manuel; Fidock, David A.
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Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance
err2022-02-07
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errSmall-Saunders, Jennifer L.; Hagenah, Laura M.; Wicht, Kathryn J.; Dhingra, Satish K.; Deni, Ioanna; Kim, Jonathan; Vendome, Jeremie; Gil-Iturbe, Eva; Roepe, Paul D.; Mehta, Monica; Mancia, Filippo; Quick, Matthias; Eppstein, Margaret J.; Fidock, David A.
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Artemisinin-Based Drugs Target the Plasmodium falciparum Heme Detoxification Pathway
err2021-03-18
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errRibbiso, Kaleab A.; Heller, Laura E.; Taye, Abigail; Julian, Erin; Willems, Andreas, V; Roepe, Paul D.
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An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion
err2019-06-06
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errThornton, L. Brock; Teehan, Paige; Floyd, Katherine; Cochrane, Christian; Bergmann, Amy; Riegel, Bryce; Stasic, Andrew J.; Di Cristina, Manlio; Moreno, Silvia N. J.; Roepe, Paul D.; Dou, Zhicheng
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PIK-ing New Malaria Chemotherapy
err2018-11-01
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PREAI
errHassett, Matthew R.; Roepe, Paul D.
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Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter
err2018-09-11
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errLee, Andrew H.; Dhingra, Satish K.; Lewis, Ian A.; Singh, Maneesh K.; Siriwardana, Amila; Dalal, Seema; Rubiano, Kelly; Klein, Matthias S.; Baska, Katelynn S.; Krishna, Sanjeev; Klemba, Michael; Roepe, Paul D.; Llinas, Manuel; Garcia, Celia R. S.; Fidock, David A.
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Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology
err2016-11-10
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errGabryszewski, Stanislaw J.; Dhingra, Satish K.; Combrinck, Jill M.; Lewis, Ian A.; Callaghan, Paul S.; Hassett, Matthew R.; Siriwardana, Amila; Henrich, Philipp P.; Lee, Andrew H.; Gnadig, Nina F.; Musset, Lise; Llinas, Manuel; Egan, Timothy J.; Roepe, Paul D.; Fidock, David A.
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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
err2015-09-25
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errMott, Bryan T.; Eastman, Richard T.; Guha, Rajarshi; Sherlach, Katy S.; Siriwardana, Amila; Shinn, Paul; McKnight, Crystal; Michael, Sam; Lacerda-Queiroz, Norinne; Patel, Paresma R.; Khine, Pwint; Sun, Hongmao; Kasbekar, Monica; Aghdam, Nima; Fontaine, Shaun D.; Liu, Dongbo; Mierzwa, Tim; Mathews-Griner, Lesley A.; Ferrer, Marc; Renslo, Adam R.; Inglese, James; Yuan, Jing; Roepe, Paul D.; Su, Xin-zhuan; Thomas, Craig J.
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Drug resistance associated membrane proteins
err2014-03-20
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errSherlach, Katy S.; Roepe, Paul D.
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UV-triggered Affinity Capture Identifies Interactions between the Plasmodium falciparum Multidrug Resistance Protein 1 (PfMDR1) and Antimalarial Agents in Live Parasitized Cells
err2013-08-01
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errBrunner, Ralf; Ng, Caroline L.; Aissaoui, Hamed; Akabas, Myles H.; Boss, Christoph; Brun, Reto; Callaghan, Paul S.; Corminboeuf, Olivier; Fidock, David A.; Frame, Ithiel J.; Heidmann, Bibia; Le Bihan, Amelie; Jenoe, Paul; Mattheis, Corinna; Moes, Suzette; Mueller, Ingrid B.; Paguio, Michelle; Roepe, Paul D.; Siegrist, Romain; Voss, Till; Welford, Richard W. D.; Wittlin, Sergio; Binkert, Christoph
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Antiproliferative and Antiplasmodial Dimeric Phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest
err2013-01-03
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errHarinantenaina, Liva; Bowman, Jessica D.; Brodie, Peggy J.; Slebodnick, Carla; Callmander, Martin W.; Rakotobe, Etienne; Randrianaivo, Richard; Rasamison, Vincent E.; Gorka, Alexander; Roepe, Paul D.; Cassera, Maria B.; Kingston, David G. I.
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Cytostatic versus Cytocidal Activities of Chloroquine Analogues and Inhibition of Hemozoin Crystal Growth
err2013-01-01
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errGorka, Alexander P.; Alumasa, John N.; Sherlach, Katy S.; Jacobs, Lauren M.; Nickley, Katherine B.; Brower, Jonathan P.; de Dios, Angel C.; Roepe, Paul D.
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Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum
err2012-05-01
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errDinio, Theresa; Gorka, Alexander P.; McGinniss, Andrew; Roepe, Paul D.; Morgan, Jeremy B.
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