Reto Brun - Publications, H-index & Citations

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis

IF5.9

2023-04-01

OAAI

Farahat, Abdelbasset A.; Kumar, Arvind; Wenzler, Tanja; Brun, Reto; Paul, Ananya; Guo, Pu; Wilson, W. David; Boykin, David W.

New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: Synthesis, in vitro and in vivo biological evaluation, and molecular modelling studies

IF6.8

2022-03-18

OAAI

Smith, Alasdair; Wall, Richard J.; Patterson, Stephen; Rowan, Tim; Vidal, Eva Rico; Stojanovski, Laste; Huggett, Margaret; Hampton, Shahienaz E.; Thomas, Michael G.; Lopez, Victoriano Corpas; Gillingwater, Kirsten; Duke, Jeff; Napier, Grant; Peter, Rose; Vitouley, Herve S.; Harrison, Justin R.; Milne, Rachel; Jeacock, Laura; Baker, Nicola; Davis, Susan H.; Simeons, Frederick; Riley, Jennifer; Horn, David; Brun, Reto; Zuccotto, Fabio; Witty, Michael J.; Wyllie, Susan; Read, Kevin D.; Gilbert, Ian H.

Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles

IF5.9

2021-10-01

PREAI

Arafa, Reem K.; Ismail, Mohamed A.; Wenzler, Tanja; Brun, Reto; Paul, Ananya; Wilson, W. David; Alakhdar, Amira A.; Boykin, David W.

A Near-Complete Series of Four Atropisomeric Jozimine A2-Type Naphthylisoquinoline Dimers with Antiplasmodial and Cytotoxic Activities and Related Alkaloids from Ancistrocladus abbreviatus

IF5.9

2021-10-01

PREAI

Doganc, Fatima; Celik, Ismail; Eren, Gokcen; Kaiser, Marcel; Brun, Reto; Goker, Hakan

Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8′-Coupling Site, from the Congolese Liana Ancistrocladus ealaensis, Targeting Pancreatic Cancer Cells

IF3.6

2019-10-23

PREAI

Fayez, Shaimaa; Li, Jun; Feineis, Doris; Assi, Laurent Ake; Kaiser, Marcel; Brun, Reto; Anany, Mohamed A.; Wajant, Harald; Bringmann, Gerhard

An Unusually Broad Series of Seven Cyclombandakamines, Bridged Dimeric Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ealaensis

IF3.6

2019-10-20

OAAI

Tshitenge, Dieudonne Tshitenge; Bruhn, Torsten; Feineis, Doris; Schmidt, David; Mudogo, Virima; Kaiser, Marcel; Brun, Reto; Wuerthner, Frank; Awale, Suresh; Bringmann, Gerhard

SCIENTIFIC REPORTS

IF3.9

2019-07-08

OAAI

Tshitenge, Dieudonne Tshitenge; Bruhn, Torsten; Feineis, Doris; Mudogo, Virima; Kaiser, Marcel; Brun, Reto; Bringmann, Gerhard

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-innidazole Derivatives as Antiprotozoal Agents

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

IF6.8

2019-01-07

PREAI

Saccoliti, Francesco; Madia, Valentina Noemi; Tudino, Valeria; De Leo, Alessandro; Pescatori, Luca; Messore, Antonella; De Vita, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; Maser, Pascal; Calvet, Claudia M.; Jennings, Gareth K.; Podust, Larissa M.; Pepe, Giacomo; Cirilli, Roberto; Faggi, Cristina; Di Marco, Annalise; Battista, Maria Rosaria; Summa, Vincenzo; Costi, Roberta; Di Santo, Roberto

Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors

IF5.9

2018-08-01

PREAI

Saccoliti, Francesco; Madia, Valentina Noemi; Tudino, Valeria; De Leo, Alessandro; Pescatori, Luca; Messore, Antonella; De Vita, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; Maser, Pascal; Calvet, Claudia Magalhaes; Jennings, Gareth K.; Podust, Larissa M.; Costi, Roberta; Di Santo, Roberto

2H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design

IF6.8

2018-03-29

PREAI

Giroud, Maude; Dietzel, Uwe; Anselm, Lilli; Banner, David; Kuglstatter, Andreas; Benz, Jorg; Blanc, Jean-Baptiste; Gaufreteau, Delphine; Liu, Haixia; Lin, Xianfeng; Stich, August; Kuhn, Bernd; Schuler, Franz; Kaiser, Marcel; Brun, Reto; Schirmeister, Tanja; Kisker, Caroline; Diederich, Francois; Haap, Wolfgang

Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities

IF6.8

2018-03-29

PREAI

Giroud, Maude; Kuhn, Bernd; Saint-Auret, Sarah; Kuratli, Christoph; Martin, Rainer E.; Schuler, Franz; Diederich, Francois; Kaiser, Marcel; Brun, Reto; Schirmeister, Tanja; Haap, Wolfgang

Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections

IF3.6

2018-03-21

PREAI

Tshitenge, Dieudonne Tshitenge; Feineis, Doris; Mudogo, Virima; Kaiser, Marcel; Brun, Reto; Seo, Ean-Jeong; Efferth, Thomas; Bringmann, Gerhard

CHEMMEDCHEM

IF3.4

2018-02-16

PREAI

Uliassi, Elisa; Piazzi, Lorna; Belluti, Federica; Mazzanti, Andrea; Kaiser, Marcel; Brun, Reto; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura

Sesquiterpene Lactones from Vernonia cinerascens Sch Bip. and Their in Vitro Antitrypanosomal Activity

MOLECULES

IF4.6

2018-01-27

OAAI

Kimani, Njogu M.; Matasyoh, Josphat C.; Kaiser, Marcel; Brun, Reto; Schmidt, Thomas J.

Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

Antiprotozoal Sesquiterpene Lactones and Other Constituents from Tarchonanthus camphoratus and Schkuhria pinnata

IF5.9

2018-01-01

OAAI

Farahat, Abdelbasset A.; Ismail, Mohamed A.; Kumar, Arvind; Wenzler, Tanja; Brun, Reto; Paul, Ananya; Wilson, W. David; Boykin, David W.

Antiprotozoal Spirombandakamines A1 and A2, Fused Naphthylisoquinoline Dimers from a Congolese Ancistrocladus Plant

IF3.6

2017-12-15

PREAI

Kimani, Njogu M.; Matasyoh, Josphat C.; Kaiser, Marcel; Brun, Reto; Schmidt, Thomas J.

ORGANIC LETTERS

IF5

2017-11-30

PREAI

Lombe, Blaise Kimbadi; Bruhn, Torsten; Feineis, Doris; Mudogo, Virima; Brun, Reto; Bringmann, Gerhard

Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line