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Durability of immune response after SARS-CoV-2 vaccination in patients with chronic liver disease Song, Ruixin; Yang, Chao; Li, Qianqian; Wang, Jiayin; Chen, Jing; Sun, Kai; Lv, Hongmin; Yang, Yankai; Liang, Jing; Ye, Qing; Gao, YanYing; Li, Jun; Li, Ying; Yan, Junqing; Liu, Ying; Wang, Tao; Liu, Changen; Zhu, Ping; Wang, Fei; Yin, Weili; Xiang, Huiling 分享 收藏
Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase Inhibitor Parcella, Kyle; Wang, Tao; Eastman, Kyle; Zhang, Zhongxing; Yin, Zhiwei; Patel, Manoj; Tu, Yong; Zheng, Barbara Zhizhen; Walker, Michael A.; Saulnier, Mark G.; Frennesson, David; Bowsher, Michael; Gillis, Eric; Peese, Kevin; Belema, Makonen; Cianci, Christopher; Dicker, Ira B.; McAuli, Brian; Ding, Bo; Falk, Paul; Simmermacher, Jean; Parker, Dawn D.; Sivaprakasam, Prasanna; Kish, Kevin; Lewis, Hal; Hanumegowda, Umesh; Jenkins, Susan; Kadow, John F.; Krystal, Mark; Meanwell, Nicholas A.; Naidu, B. Narasimhulu 分享 收藏
Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles Jecs, Edgars; Tahirovic, Yesim A.; Wilson, Robert J.; Miller, Eric J.; Kim, Michelle; Truax, Valarie; Nguyen, Huy H.; Akins, Nicholas S.; Saindane, Manohar; Wang, Tao; Sum, Chi S.; Cvijic, Mary E.; Schroeder, Gretchen M.; Burton, Samantha L.; Derdeyn, Cynthia A.; Xu, Lingjie; Jiang, Yi; Wilson, Lawrence J.; Liotta, Dennis C. 分享 收藏
Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure Meng, Wei; Pi, Zulan; Brigance, Robert; Rossi, Karen A.; Schumacher, William A.; Bostwick, Jeffrey S.; Gargalovic, Peter S.; Onorato, Joelle M.; Luk, Chiuwa E.; Generaux, Claudia N.; Wang, Tao; Wexler, Ruth R.; Finlay, Heather J. 分享 收藏
Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases Cheng, Peter T. W.; Kaltenbach, Robert F.; Zhang, Hao; Shi, Jun; Tao, Shiwei; Li, Jun; Kennedy, Lawrence J.; Walker, Steven J.; Shi, Yan; Wang, Ying; Dhanusu, Suresh; Reddigunta, Ramesh; Kumaravel, Selvakumar; Jusuf, Sutjano; Smith, Daniel; Krishnananthan, Subramaniam; Li, Jianqing; Wang, Tao; Heiry, Rebekah; Sum, Chi Shing; Kalinowski, Stephen S.; Hung, Chen-Pin; Chu, Ching-Hsuen; Azzara, Anthony, V; Ziegler, Milinda; Burns, Lisa; Zinker, Bradley A.; Boehm, Stephanie; Taylor, Joseph; Sapuppo, Julia; Mosure, Kathy; Everlof, Gerry; Guarino, Victor; Zhang, Lisa; Yang, Yanou; Ruan, Qian; Xu, Carrie; Apedo, Atsu; Traeger, Sarah C.; Cvijic, Mary Ellen; Lentz, Kimberley A.; Tirucherai, Giridhar; Sivaraman, Lakshmi; Robl, Jeffrey; Ellsworth, Bruce A.; Rosen, Glenn; Gordon, David A.; Soars, Matthew G.; Gill, Michael; Murphy, Brian J. 分享 收藏
Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists Pi, Zulan; Johnson, James A.; Meng, Wei; Phillips, Monique; Schumacher, William A.; Bostwick, Jeffrey S.; Gargalovic, Peter S.; Onorato, Joelle M.; Generaux, Claudia N.; Wang, Tao; He, Yan; Gordon, David A.; Wexler, Ruth R.; Finlay, Heather J. 分享 收藏
Amino-Heterocycle Tetrahydroisoquinoline CXCR4 Antagonists with Improved ADME Profiles via Late-Stage Buchwald Couplings 氨基杂环四氢异喹啉CXCR4拮抗剂，通过后期Buchwald偶联改善ADME谱 Nguyen, Huy H.; Tahirovic, Yesim A.; Truax, Valarie M.; Wilson, Robert J.; Jecs, Edgars; Miller, Eric J.; Kim, Michelle B.; Akins, Nicholas S.; Xu, Lingjie; Jiang, Yi; Wang, Tao; Sum, Chi S.; Cvijic, Mary E.; Schroeder, Gretchen M.; Wilson, Lawrence J.; Liotta, Dennis C. 分享 收藏
Discovery of BMS-986318, a Potent Nonbile Acid FXR Agonist for the Treatment of Nonalcoholic Steatohepatitis 发现BMS-986318，一种有效的非胆汁酸FXR激动剂，用于治疗非酒精性脂肪性肝炎 Carpenter, Joseph; Wu, Gang; Wang, Ying; Cook, Erica M.; Wang, Tao; Sitkoff, Doree; Rossi, Karen A.; Mosure, Kathy; Zhuo, Xiaoliang; Cao, Gary G.; Ziegler, Milinda; Azzara, Anthony, V; Krupinski, Jack; Soars, Matthew G.; Ellsworth, Bruce Alan; Wacker, Dean A. 分享 收藏
Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate Johnson, James A.; Kim, Soong-Hoon; Jiang, Ji; Phillips, Monique; Schumacher, William A.; Bostwick, Jeffrey S.; Gargalovic, Peter S.; Onorato, Joelle M.; Luk, Chiuwa E.; Generaux, Claudia; He, Yan; Chen, Xue-Qing; Xu, Carrie; Galella, Michael A.; Wang, Tao; Gordon, David A.; Wexler, Ruth R.; Finlay, Heather J. 分享 收藏
In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure Gargalovic, Peter; Wong, Pancras; Onorato, Joelle; Finlay, Heather; Wang, Tao; Yan, Mujing; Crain, Earl; St-Onge, Stephane; Heroux, Madeleine; Bouvier, Michel; Xu, Carrie; Chen, Xue-Qing; Generaux, Claudia; Lawrence, Michael; Wexler, Ruth; Gordon, David 分享 收藏
Simvastatin therapy in adolescent mice attenuates HFD-induced depression-like behavior by reducing hippocampal neuroinflammation Wu, Huali; Lv, Wenting; Pan, Qi; Kalavaguntaa, Praveen Kumar; Liu, Qiongzhen; Qin, Guohong; Cai, Minxuan; Zhou, Liangliang; Wang, Tao; Xia, Zhenjiang; Shang, Jing 分享 收藏
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties Nguyen, Huy H.; Kim, Michelle B.; Wilson, Robert J.; Butch, Christopher J.; Kuo, Katie M.; Miller, Eric J.; Tahirovic, Yesim A.; Jecs, Edgars; Truax, Valarie M.; Wang, Tao; Sum, Chi S.; Cvijic, Mary E.; Schroeder, Gretchen M.; Wilson, Lawrence J.; Liotta, Dennis C. 分享 收藏
Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir 人类免疫缺陷病毒1型 (HIV-1) 附着抑制剂Temsavir及其膦酰氧基甲基前药Fostemsavir的发现 Wang, Tao; Ueda, Yasu; Zhang, Zhongxing; Yin, Zhiwei; Matiskella, John; Pearce, Bradley C.; Yang, Zheng; Zheng, Ming; Parker, Dawn D.; Yamanaka, Gregory A.; Gong, Yi-Fei; Ho, Hsu-Tso; Colonno, Richard J.; Langley, David R.; Lin, Pin-Fang; Meanwell, Nicholas A.; Kadow, John F. 分享 收藏
Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties 基于N-烷基哌嗪侧链的CXCR4拮抗剂的发现，具有改善的药物特性 Tahirovic, Yesim A.; Truax, Valarie M.; Wilson, Robert J.; Jecs, Edgars; Nguyen, Huy H.; Miller, Eric J.; Kim, Michelle B.; Kuo, Katie M.; Wang, Tao; Sum, Chi S.; Cvijic, Mary E.; Schroeder, Gretchen M.; Wilson, Lawrence J.; Liotta, Dennis C. 分享 收藏
Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in Vitro ADMET Properties Miller, Eric J.; Jecs, Edgars; Truax, Valarie M.; Katzman, Brooke M.; Tahirovic, Yesim A.; Wilson, Robert J.; Kuo, Katie M.; Kim, Michelle B.; Nguyen, Huy H.; Saindane, Manohar T.; Zhao, Huanyu; Wang, Tao; Sum, Chi S.; Cvijic, Mary E.; Schroeder, Gretchen M.; Wilson, Lawrence J.; Liotta, Dennis C. 分享 收藏
Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists Shi, Jun; Gu, Zhengxiang; Jurica, Elizabeth Anne; Wu, Ximao; Haque, Lauren E.; Williams, Kristin N.; Hernandez, Andres S.; Hong, Zhenqiu; Gao, Qi; Dabros, Marta; Davulcu, Akin H.; Mathur, Arvind; Rampulla, Richard A.; Gupta, Arun Kumar; Jayaram, Ramya; Apedo, Atsu; Moore, Douglas B.; Liu, Heng; Kunselman, Lori K.; Brady, Edward J.; Wilkes, Jason J.; Zinker, Bradley A.; Cai, Hong; Shu, Yue-Zhong; Sun, Qin; Dierks, Elizabeth A.; Foster, Kimberly A.; Xu, Carrie; Wang, Tao; Panemangalore, Reshma; Cvijic, Mary Ellen; Xie, Chunshan; Cao, Gary G.; Zhou, Min; Krupinski, John; Whaley, Jean M.; Robl, Jeffrey A.; Ewing, William R.; Ellsworth, Bruce Alan 分享 收藏
Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains 具有刚性侧链的新型四氢异喹啉CXCR4拮抗剂的合成 Jecs, Edgars; Miller, Eric J.; Wilson, Robert J.; Nguyen, Huy H.; Tahirovic, Yesim A.; Katzman, Brook M.; Truax, Valarie M.; Kim, Michelle B.; Kuo, Katie M.; Wang, Tao; Sum, Chi S.; Cvijic, Mary E.; Schroeder, Gretchen M.; Wilson, Lawrence J.; Liotta, Dennis C. 分享 收藏
Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir HIV-1附着的抑制剂: Temsavir及其前药Fostemsavir的发现和开发 Meanwell, Nicholas A.; Krystal, Mark R.; Nowicka-Sans, Beata; Langley, David R.; Conlon, David A.; Eastgate, Martin D.; Grasela, Dennis M.; Timmins, Peter; Wang, Tao; Kadow, John F. 分享 收藏
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