Kirk W. Johnson - Publications, H-index & Citations

Kirk W. Johnson

ammax bio

52H指数

169论文数

1.0W被引数

收录论文 69

发表时间

Pharmacokinetics and Pharmacodynamics of an Anti-CSF1 Receptor Antibody in the Intra-articular Treatment of Tenosynovial Giant Cell Tumor 抗-CSF1受体抗体在腱鞘巨细胞瘤关节内治疗中的药代动力学和药效学

European Journal of Cancer

IF7.1

2025-09-06

PREAI

Michiel van de Sande; Kirk Johnson; Kirsten van Langevelde; Thomas Scharschmidt; Laman Alani; Dorothy Nguyen; Tiffany Nguyen; Chinglin Lai; Hans Gelderblom

Preclinical and clinical evaluation of LY3451838, a PACAP-neutralizing monoclonal antibody, in randomized, double-blind, placebo-controlled phase 1 and phase 2 studies involving healthy adults and adults with treatment-resistant migraine LY3451838的药效学与临床评估，该药是一种PACAP中和单克隆抗体，在涉及健康成年人和治疗抵抗性偏头痛成年人的随机、双盲、安慰剂对照的1期和2期研究中的评估

Cephalalgia

IF4.6

2025-08-21

OAAI

Michael P. Johnson; Judith Krikke-Workel; Chetan N. Patel; S. Michelle Morin; P. Kellie Turner; Kristie A. Clark; David Donley; Yan Jin; Kirk W. Johnson; Maurice Vincent; John R. Stille; Lisa M. Broad; Ashok Patel

Galcanezumab reduces trigeminal nociception and is effective in preclinical models of migraine and trigeminal autonomic cephalalgias 加卡纳zumab（Galcanezumab）可降低三叉神经痛觉过敏，并在偏头痛和三叉神经自主性头痛的预临床模型中显示出疗效。

IF0

2025-07-21

OAAI

Marta Vila-Pueyo PhD; Peter J. Goadsby MD, PhD; Kirk W. Johnson PhD; Philip R. Holland PhD

Plasma calcitonin gene-related peptide and nerve growth factor as headache and pain biomarkers in recently deployed soldiers with and without a recent concussion

HEADACHE

IF4

2023-10-05

PREAI

Scher, Ann I.; Mcginley, James S.; Vandam, Lyndsey R.; Campbell, Amanda M.; Chai, Xiyun; Collins, Billy; Klimp, Scott A.; Finkel, Alan G.; Schwab, Karen; Lipton, Richard B.; Johnson, Kirk W.

TRPA1 Antagonist LY3526318 Inhibits the Cinnamaldehyde-Evoked Dermal Blood Flow Increase: Translational Proof of Pharmacology

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2023-09-21

OAAI

Bamps, Dorien; Blockeel, Anthony James; Dreesen, Erwin; Marynissen, Heleen; Laenen, Jolien; Van Hecken, Anne; Wilke, August; Shahabi, Shahram; Johnson, Kirk W.; Collins, Emily Catherine; Broad, Lisa M.; Phillips, Keith G.; de Hoon, Jan

Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists

HEADACHE

IF4

2022-07-13

OAAI

Johnson, Kirk W.; Li, Xia; Huang, Xiaofang; Heinz, Beverly A.; Yu, Jianliang; Li, Baolin

The selective 5-HT1F receptor agonist lasmiditan inhibits trigeminal nociceptive processing: Implications for migraine and cluster headache

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2021-11-16

OAAI

Vila-Pueyo, Marta; Page, Keith; Murdock, Paul R.; Loraine, Howard J.; Woodrooffe, Amanda J.; Johnson, Kirk W.; Goadsby, Peter J.; Holland, Philip R.

Levels of prolactin and testosterone and associated sexual dysfunction and breast abnormalities in men with schizophrenia treated with antipsychotic medications

JOURNAL OF PSYCHIATRIC RESEARCH

IF3.2

2021-11-01

OAAI

Redman, Brianne; Kitchen, Chris; Johnson, Kirk W.; Bezwada, Padma; Kelly, Deanna L.

Evaluation of LY573144 (lasmiditan) in a preclinical model of medication overuse headache

CEPHALALGIA

IF4.6

2020-06-24

OAAI

Rau, Jill C.; Navratilova, Edita; Oyarzo, Janice; Johnson, Kirk W.; Aurora, Sheena K.; Schwedt, Todd J.; Dodick, David W.; Porreca, Frank

Lasmiditan mechanism of action - review of a selective 5-HT1Fagonist

JOURNAL OF HEADACHE AND PAIN

IF7.9

2020-06-10

OAAI

Clemow, David B.; Johnson, Kirk W.; Hochstetler, Helen M.; Ossipov, Michael H.; Hake, Ann M.; Blumenfeld, Andrew M.

Lasmiditan inhibits calcitonin gene-related peptide release in the rodent trigeminovascular system

PAIN

IF5.5

2020-01-22

OAAI

Labastida-Ramirez, Alejandro; Rubio-Beltran, Eloisa; Haanes, Kristian A.; Chan, Kayi Y.; Garrelds, Ingrid M.; Johnson, Kirk W.; Danser, Alexander H. J.; Villalon, Carlos M.; MaassenVanDenBrink, Antoinette

Characterization of binding, functional activity, and contractile responses of the selective 5-HT1F receptor agonist lasmiditan

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2019-11-07

OAAI

Rubio-Beltran, Eloisa; Labastida-Ramirez, Alejandro; Haanes, Kristian A.; van den Bogaerdt, Antoon; Bogers, Ad J. J. C.; Zanelli, Eric; Meeus, Laurent; Danser, A. H. Jan; Gralinski, Michael R.; Senese, Peter B.; Johnson, Kirk W.; Kovalchin, Joseph; Villalon, Carlos M.; MaassenVanDenBrink, Antoinette

Peripheral and central nervous system distribution of the CGRP neutralizing antibody [125I] galcanezumab in male rats CGRP中和抗体 [125I] galcanezumab在雄性大鼠中的周围和中枢神经系统分布

CEPHALALGIA

IF4.6

2019-04-19

PREAI

Johnson, Kirk W.; Morin, S. Michelle; Wroblewski, Victor J.; Johnson, Michael P.

CGRP and the Trigeminal System in Migraine CGRP和偏头痛的三叉神经系统

HEADACHE

IF4

2019-04-14

308

OAAI

Iyengar, Smriti; Johnson, Kirk W.; Ossipov, Michael H.; Aurora, Sheena K.

A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1-/- mouse model of KATP hyperinsulinism

MABS

IF7.3

2018-06-01

OAAI

Patel, Puja; Charles, Lawrenshey; Corbin, John; Goldfine, Ira D.; Johnson, Kirk; Rubin, Paul; De Leon, Diva D.

Potentiation of IL-2's antitumor efficacy without compromised tolerability by a novel human antibody

MOLECULAR CANCER THERAPEUTICS

IF5.5

2018-01-01

PREAI

Johnson, Kirk; Li, Ou; Liu, Xiaohe; Beviglia, Lucia

Improved coagulation in bleeding disorders by non-anticoagulant sulfated polysaccharides (NASP)

THROMBOSIS AND HAEMOSTASIS

IF4.3

2017-11-28

PREAI

Liu, TY; Scallan, CD; Broze, GJ; Patarroyo-White, S; Pierce, GF; Johnson, KW

Human mast cells release the migraine-inducing factor pituitary adenylate cyclase-activating polypeptide (PACAP)

CEPHALALGIA

IF4.6

2017-11-05

PREAI

Okragly, Angela J.; Morin, S. Michelle; DeRosa, David; Martin, Andrea P.; Johnson, Kirk W.; Johnson, Michael P.; Benschop, Robert J.

Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-lmidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-10-10

PREAI

Wagman, Allan S.; Boyce, Rustum S.; Brown, Sean P.; Fang, Eric; Goff, Dane; Jansen, Johanna M.; Le, Vincent P.; Levine, Barry H.; Ng, Simon C.; Ni, Zhi-Jie; Nuss, John M.; Pfister, Keith B.; Ramurthy, Savithri; Renhowe, Paul A.; Ring, David B.; Shu, Wei; Subramanian, Sharadha; Zhou, Xiaohui A.; Shafer, Cynthia M.; Harrison, Stephen D.; Johnson, Kirk W.; Bussiere, Dirksen E.

Effects of ibudilast on oxycodone-induced analgesia and subjective effects in opioid-dependent volunteers

DRUG AND ALCOHOL DEPENDENCE

IF3.6

2017-09-01

PREAI

Cooper, Z. D.; Johnson, K. W.; Vosburg, S. K.; Sullivan, M. A.; Manubay, J.; Martinez, D.; Jones, J. D.; Saccone, P. A.; Comer, S. D.

研究方向