未登录 Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines Elrick, Hillary; Peterson, Kevin A.; Willis, Brandon J.; Lanza, Denise G.; Acar, Elif F.; Ryder, Edward J.; Teboul, Lydia; Kasparek, Petr; Birling, Marie-Christine; Adams, David J.; Bradley, Allan; Braun, Robert E.; Brown, Steve D.; Caulder, Adam; Codner, Gemma F.; Demayo, Francesco J.; Dickinson, Mary E.; Doe, Brendan; Duddy, Graham; Gertsenstein, Marina; Goodwin, Leslie O.; Herault, Yann; Lintott, Lauri G.; Lloyd, K. C. Kent; Lorenzo, Isabel; Mackenzie, Matthew; Mallon, Ann-Marie; Mckerlie, Colin; Parkinson, Helen; Ramirez-Solis, Ramiro; Seavitt, John R.; Sedlacek, Radislav; Skarnes, William C.; Smedley, Damien; Wells, Sara; White, Jacqueline K.; Wood, Joshua A.; Akhtar, Shaheen; Allan, Alasdair J.; Allen, Susan; Andre, Philippe; Archer, Daniel; Atkins, Sarah; Avery, Ruth; Ayadi, Abdel; Barrett, Daniel; Beyetinova, Tanya; Bell, Toni; Berry, Melissa; Boroviak, Katharina; Bottomley, Joanna; Brendler-Spaeth, Tim; Brown, Ellen; Burvill, Jonathan; Bussell, James; Cardeno, Charis; Carter, Rebecca V.; Castellanos-Penton, Patricia; Christou, Skevoulla; Clark, Greg; Clarke, Shannon; Cleak, James; Crawford, Ronnie; Creighton, Amie; Cruz, Maribelle; Danisment, Ozge; Davis, Charlotte; Doran, Joanne; Erbs, Valerie; Fan-Lan, Qing; Fell, Rachel; Feng, He; Fougerolle, Jean-Victor; Fower, Alex; Frake, Gemma; Fray, Martin D.; Galli, Antonella; Gannon, David; Gardiner, Wendy J.; Gaspero, Angelina; Gleeson, Diane; Godbehere, Chris; Grau, Evelyn; Griffiths, Mark; Griggs, Nicola; Grimsrud, Kristin; Hazeltine, Sarah; Hutchison, Marie; Ingle, Catherine; Iyer, Vivek; Jager, Kayla; Joeng, Joanna; Kales, Susan; Kaur, Perminder; Kenyon, Janet; Kopkanova, Jana; Kujath, Christelle; Kundi, Helen; Kutny, Peter; Laurin, Valerie; Lejeay, Sandrine; Lelliott, Christopher; Loeffler, Jorik; Lorentz, Romain; Mccabe, Christopher V.; Malzer, Elke; Matthews, Peter; Maswood, Ryea; Mckay, Matthew; Meehan, Terrence; Melvin, David; Murphy, Alison; Nakhuda, Asif; Patel, Amit; Paulavets, Ilya; Pavlovic, Guillaume; Pawelka, Ashley; Pike, Fran J.; Platte, Radka; Price, Peter D.; Rajaya, Kiran; Reddy, Shalini; Rich, Whitney; Rosen, Barry; Ross, Victoria; Ruhe, Mark; Santos, Luis; Schaeffer, Laurence; Schwiening, Alix; Selloum, Mohammed; Sethi, Debarati; Sidiangco, Jan R.; Sinclair, Caroline; Sins, Elodie; Sleep, Gillian; Sorg, Tania; Starbuck, Becky; Stewart, Michelle; Swash, Holly; Thomas, Mark; Tondat, Sandra; Urban, Rachel; Urbanova, Jana; Varley, Susan; Von Schiller, Dominque; Wardle-Jones, Hannah; Weavers, Lauren; Woods, Michael; Murray, Stephen A.; Heaney, Jason D.; Nutter, Lauryl M. J. 分享 收藏
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy Spielmann, Nadine; Miller, Gregor; Oprea, Tudor I.; Hsu, Chih-Wei; Fobo, Gisela; Frishman, Goar; Montrone, Corinna; Haseli Mashhadi, Hamed; Mason, Jeremy; Munoz Fuentes, Violeta; Leuchtenberger, Stefanie; Ruepp, Andreas; Wagner, Matias; Westphal, Dominik S.; Wolf, Cordula; Goerlach, Agnes; Sanz-Moreno, Adrian; Cho, Yi-Li; Teperino, Raffaele; Brandmaier, Stefan; Sharma, Sapna; Galter, Isabella Rikarda; Oestereicher, Manuela A.; Zapf, Lilly; Mayer-Kuckuk, Philipp; Rozman, Jan; Teboul, Lydia; Bunton-Stasyshyn, Rosie K. A.; Cater, Heather; Stewart, Michelle; Christou, Skevoulla; Westerberg, Henrik; Willett, Amelia M.; Wotton, Janine M.; Roper, Willson B.; Christiansen, Audrey E.; Ward, Christopher S.; Heaney, Jason D.; Reynolds, Corey L.; Prochazka, Jan; Bower, Lynette; Clary, David; Selloum, Mohammed; Bou About, Ghina; Wendling, Olivia; Jacobs, Hugues; Leblanc, Sophie; Meziane, Hamid; Sorg, Tania; Audain, Enrique; Gilly, Arthur; Rayner, Nigel W.; Aguilar-Pimentel, Juan A.; Becker, Lore; Garrett, Lillian; Hoelter, Sabine M.; Amarie, Oana V.; Calzada-Wack, Julia; Klein-Rodewald, Tanja; da Silva-Buttkus, Patricia; Lengger, Christoph; Stoeger, Claudia; Gerlini, Raffaele; Rathkolb, Birgit; Mayr, Daniela; Seavitt, John; Gaspero, Angelina; Green, Jennie R.; Garza, Arturo; Bohat, Ritu; Wong, Leeyean; Mcelwee, Melissa L.; Kalaga, Sowmya; Rasmussen, Tara L.; Lorenzo, Isabel; Lanza, Denise G.; Samaco, Rodney C.; Veeraragaven, Surabi; Gallegos, Juan J.; Kasparek, Petr; Petrezselyova, Silvia; King, Ruairidh; Johnson, Sara; Cleak, James; Szkoe-Kovacs, Zsombor; Codner, Gemma; Mackenzie, Matthew; Caulder, Adam; Kenyon, Janet; Gardiner, Wendy; Phelps, Hayley; Hancock, Rhys; Norris, Claire; Moore, Michayla A.; Seluke, Audrie M.; Urban, Rachel; Kane, Coleen; Goodwin, Leslie O.; Peterson, Kevin A.; Mckay, Matthew; Cook, Jenn J.; Lowy, Jacob P.; Mcfarland, Michael; Wood, Joshua A.; Willis, Brandon J.; Tolentino, Heather; Tolentino, Todd; Schuchbauer, Michael; Salazar, Jason; Johnson, Jennifer; Munson, Rebecca; Ayadi, Abdel; Pavlovic, Guillaume; Birling, Marie-Christine; Jacquot, Sylvie; Ali-Hadji, Dalila; Charles, Philippe; Andre, Philippe; Champy, Marie-France; Riet, Fabrice; Vukobradovic, Igor; Berberovic, Zorana; Qu, Dawei; Guo, Ruolin; D'Souza, Abigail; Huang, Ziyue; Camilleri, Susan; Ganguly, Milan; Adissu, Hibret; Eskandarian, Mohammed; Shang, Xueyuan; Duffin, Kyle; Xu, Catherine; Roberton, Kyle; Laurin, Valerie; Lan, Qing; Sleep, Gillian; Creighton, Amie; Lintott, Lauri; Gertsenstein, Marina; Pereira, Monica; Tondat, Sandra; Patel, Amit; Cruz, Maribelle; Bezginov, Alex; Miller, David; Hy, Wang; Yoshiki, Atsushi; Tanaka, Nobuhiko; Tamura, Masaru; Liu, Zhiwei; Ermakova, Olga; Ferrara, Anna; Fruscoloni, Paolo; Seisenberger, Claudia; Buerger, Antje; Giesert, Florian; Ambrose, J. C.; Gam, Arumu P.; Bevers, R.; Bleda, M.; Boardman-Pretty, F.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Fowler, T.; Giess, A.; Hamblin, A.; Henderson, S.; Hubbard, T. J. P.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Kousathanas, A.; Lahnstein, L.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; Maleady-Crowe, F.; Mcentagart, M.; Minneci, F.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; O'Donovan, P.; Odhams, C. A.; Patch, C.; Perez-Gil, D.; Pereira, M. B.; Pullinger, J.; Rahim, T.; Rendon, A.; Rogers, T.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, S. C.; Sosinsky, A.; Stuckey, A.; Tanguy, M.; Taylor-Tavares, A. L.; Thomas, E. R. A.; Thompson, S. R.; Tucci, A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Hitz, Marc-Phillip; Zeggini, Eleftheria; Wolf, Eckhard; Sedlacek, Radislav; Murray, Steven A.; Svenson, Karen L.; Braun, Robert E.; White, Jaqueline K.; Kelsey, Lois; Gao, Xiang; Shiroishi, Toshihiko; Xu, Ying; Seong, Je Kyung; Mammano, Fabio; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Meehan, Terrence F.; Parkinson, Helen; Smedley, Damian; Mallon, Ann-Marie; Wells, Sara E.; Grallert, Harald; Wurst, Wolfgang; Marschall, Susan; Fuchs, Helmut; Brown, Steve D. M.; Flenniken, Ann M.; Nutter, Lauryl M. J.; Mckerlie, Colin; Herault, Yann; Lloyd, K. C. Kent; Dickinson, Mary E.; Gailus-Durner, Valerie; Hrabe de Angelis, Martin 分享 收藏
A resource of targeted mutant mouse lines for 5,061 genes 用于5,061基因的靶向突变小鼠系的资源 Birling, Marie-Christine; Yoshiki, Atsushi; Adams, David J.; Ayabe, Shinya; Beaudet, Arthur L.; Bottomley, Joanna; Bradley, Allan; Brown, Steve D. M.; Buerger, Antje; Bushell, Wendy; Chiani, Francesco; Chin, Hsian-Jean Genie; Christou, Skevoulla; Codner, Gemma F.; DeMayo, Francesco J.; Dickinson, Mary E.; Doe, Brendan; Donahue, Leah Rae; Fray, Martin D.; Gambadoro, Alessia; Gao, Xiang; Gertsenstein, Marina; Gomez-Segura, Alba; Goodwin, Leslie O.; Heaney, Jason D.; Herault, Yann; de Angelis, Martin Hrabe; Jiang, Si-Tse; Justice, Monica J.; Kasparek, Petr; King, Ruairidh E.; Kuhn, Ralf; Lee, Ho; Lee, Young Jae; Liu, Zhiwei; Lloyd, K. C. Kent; Lorenzo, Isabel; Mallon, Ann-Marie; McKerlie, Colin; Meehan, Terrence F.; Fuentes, Violeta Munoz; Newman, Stuart; Nutter, Lauryl M. J.; Oh, Goo Taeg; Pavlovic, Guillaume; Ramirez-Solis, Ramiro; Rosen, Barry; Ryder, Edward J.; Santos, Luis A.; Schick, Joel; Seavitt, John R.; Sedlacek, Radislav; Seisenberger, Claudia; Seong, Je Kyung; Skarnes, William C.; Sorg, Tania; Steel, Karen P.; Tamura, Masaru; Tocchini-Valentini, Glauco P.; Wang, Chi-Kuang Leo; Wardle-Jones, Hannah; Wattenhofer-Donze, Marie; Wells, Sara; Wiles, Michael V.; Willis, Brandon J.; Wood, Joshua A.; Wurst, Wolfgang; Xu, Ying; Teboul, Lydia; Murray, Stephen A. 分享 收藏
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Human and mouse essentiality screens as a resource for disease gene discovery Cacheiro, Pilar; Munoz-Fuentes, Violeta; Murray, Stephen A.; Dickinson, Mary E.; Bucan, Maja; Nutter, Lauryl M. J.; Peterson, Kevin A.; Haselimashhadi, Hamed; Flenniken, Ann M.; Morgan, Hugh; Westerberg, Henrik; Konopka, Tomasz; Hsu, Chih-Wei; Christiansen, Audrey; Lanza, Denise G.; Beaudet, Arthur L.; Heaney, Jason D.; Fuchs, Helmut; Gailus-Durner, Valerie; Sorg, Tania; Prochazka, Jan; Novosadova, Vendula; Lelliott, Christopher J.; Wardle-Jones, Hannah; Wells, Sara; Teboul, Lydia; Cater, Heather; Stewart, Michelle; Hough, Tertius; Wurst, Wolfgang; Sedlacek, Radislav; Adams, David J.; Seavitt, John R.; Tocchini-Valentini, Glauco; Mammano, Fabio; Braun, Robert E.; McKerlie, Colin; Herault, Yann; de Angelis, Martin Hrabe; Mallon, Ann-Marie; Lloyd, K. C. Kent; Brown, Steve D. M.; Parkinson, Helen; Meehan, Terrence F.; Smedley, Damian; Ambrose, J. C.; Arumugam, P.; Baple, E. L.; Bleda, M.; Boardman-Pretty, F.; Boissiere, J. M.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Craig, C. E. H.; Daugherty, L. C.; de Burca, A.; Devereau, A.; Elgar, G.; Foulger, R. E.; Fowler, T.; Furio-Tari, P.; Hackett, J. M.; Halai, D.; Hamblin, A.; Henderson, S.; Holman, J. E.; Hubbard, T. J. P.; Ibanez, K.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Lahnstein, L.; Lawson, K.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; Maleady-Crowe, F.; Mason, J.; McDonagh, E. M.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; Odhams, C. A.; Patch, C.; Perez-Gil, D.; Polychronopoulos, D.; Pullinger, J.; Rahim, T.; Rendon, A.; Riesgo-Ferreiro, P.; Rogers, T.; Ryten, M.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, K. R.; Sosinsky, A.; Spooner, W.; Stevens, H. E.; Stuckey, A.; Sultana, R.; Thomas, E. R. A.; Thompson, S. R.; Tregidgo, C.; Tucci, A.; Walsh, E.; Watters, S. A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Zarowiecki, M.; Marschall, Susan; Lengger, Christoph; Maier, Holger; Seisenberger, Claudia; Buerger, Antje; Kuehn, Ralf; Schick, Joel; Hoerlein, Andreas; Oritz, Oskar; Giesert, Florian; Beig, Joachim; Kenyon, Janet; Codner, Gemma; Fray, Martin; Johnson, Sara J.; Cleak, James; Szoke-Kovacs, Zsombor; Lafont, David; Vancollie, Valerie E.; McLaren, Robbie S. B.; Hughes-Hallett, Lena; Rowley, Christine; Sanderson, Emma; Galli, Antonella; Tuck, Elizabeth; Green, Angela; Tudor, Catherine; Siragher, Emma; Dabrowska, Monika; Mazzeo, Cecilia Icoresi; Griffiths, Mark; Gannon, David; Doe, Brendan; Cockle, Nicola; Kirton, Andrea; Bottomley, Joanna; Ingle, Catherine; Ryder, Edward; Gleeson, Diane; Ramirez-Solis, Ramiro; Birling, Marie-Christine; Pavlovic, Guillaume; Ayadi, Abdel; Hamid, Meziane; About, Ghina Bou; Champy, Marie-France; Jacobs, Hugues; Wendling, Olivia; Leblanc, Sophie; Vasseur, Laurent; Chesler, Elissa J.; Kumar, Vivek; White, Jacqueline K.; Svenson, Karen L.; Wiegand, Jean-Paul; Anderson, Laura L.; Wilcox, Troy; Clark, James; Ryan, Jennifer; Denegre, James; Stearns, Tim; Philip, Vivek; Witmeyer, Catherine; Bates, Lindsay; Seavey, Zachary; Stanley, Pamela; Willet, Amelia; Roper, Willson; Creed, Julie; Moore, Michayla; Dorr, Alex; Fraungruber, Pamelia; Presby, Rose; Mckay, Matthew; Nguyen-Bresinsky, Dong; Goodwin, Leslie; Urban, Rachel; Kane, Coleen 分享 收藏
Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis 顺序诱导小鼠模型揭示Npm1突变导致Dnmt3a-mutant克隆造血的恶性转化 Loberg, Matthew A.; Bell, Rebecca K.; Goodwin, Leslie O.; Eudy, Elizabeth; Miles, Linde A.; SanMiguel, Jennifer M.; Young, Kira; Bergstrom, David E.; Levine, Ross L.; Schneider, Rebekka K.; Trowbridge, Jennifer J. 分享 收藏
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis Goodwin, Leslie O.; Splinter, Erik; Davis, Tiffany L.; Urban, Rachel; He, Hao; Braun, Robert E.; Chesler, Elissa J.; Kumar, Vivek; van Min, Max; Ndukum, Juliet; Philip, Vivek M.; Reinholdt, Laura G.; Svenson, Karen; White, Jacqueline K.; Sasner, Michael; Lutz, Cathleen; Murray, Stephen A. 分享 收藏
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Deletion of Nrip1 Extends Female Mice Longevity, Increases Autophagy, and Delays Cell Senescence Wang, Jinyu; Chen, Xundi; Osland, Jared; Gerber, Skyler J.; Luan, Chao; Delfino, Kristin; Goodwin, Leslie; Yuan, Rong 分享 收藏
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Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice Shaheen, Ranad; Anazi, Shams; Ben-Omran, Tawfeg; Seidahmed, Mohammed Zain; Caddle, L. Brianna; Palmer, Kristina; Ali, Rehab; Alshidi, Tarfa; Hagos, Samya; Goodwin, Leslie; Hashem, Mais; Wakil, Salma M.; Abouelhoda, Mohamed; Colak, Dilek; Murray, Stephen A.; Alkuraya, Fowzan S. 分享 收藏
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Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase Reinert, Rachel B.; Oberle, L. Morgan; Wek, Sheree A.; Bunpo, Piyawan; Wang, Xue Ping; Mileva, Izolda; Goodwin, Leslie O.; Aldrich, Carla J.; Durden, Donald L.; McNurlan, Margaret A.; Wek, Ronald C.; Anthony, Tracy G. 分享 收藏
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